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Degenerative protein modifications in the aging vasculature and central nervous system: a problem shared is not always halved.

Gallart-Palau X, Tan LM, Serra A, Gao Y, Ho HH, Richards AM, Kandiah N, Chen CP, Kalaria RN, Kwan Sze S.

Ageing Res Rev. 2019 May 19:100909. doi: 10.1016/j.arr.2019.100909. [Epub ahead of print] Review.


Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression.

Park JE, Tse SW, Xue G, Assisi C, Maqueda AS, Ramon GPX, Low JK, Kon OL, Tay CY, Tam JP, Sze SK.

Oncotarget. 2019 Mar 15;10(22):2136-2150. doi: 10.18632/oncotarget.26669. eCollection 2019 Mar 15.


Pellino1 specifically binds to phospho-Thr18 of p53 and is recruited to sites of DNA damage.

Dai L, Lin J, Said AB, Yau YH, Shochat SG, Ruiz-Carrillo D, Sun K, Chandrasekaran R, Sze SK, Lescar J, Cheung PC.

Biochem Biophys Res Commun. 2019 Jun 4;513(3):714-720. doi: 10.1016/j.bbrc.2019.03.095. Epub 2019 Apr 12.


Carotid Artery Disease in Post-Stroke Survivors and Effects of Enriched Environment on Stroke Pathology in a Mouse Model of Carotid Artery Stenosis.

Hase Y, Polvikoski TM, Ihara M, Hase M, Zafar R, Stevenson W, Allan LM, Ennaceur A, Horsburgh K, Gallart-Palau X, Sze SK, Kalaria RN.

Neuropathol Appl Neurobiol. 2019 Apr 4. doi: 10.1111/nan.12550. [Epub ahead of print]


Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift.

Park JE, Dutta B, Tse SW, Gupta N, Tan CF, Low JK, Yeoh KW, Kon OL, Tam JP, Sze SK.

Oncogene. 2019 Mar 12. doi: 10.1038/s41388-019-0782-x. [Epub ahead of print]


Immunomic Identification of Malaria Antigens Associated With Protection in Mice.

Siau A, Huang X, Loh HP, Zhang N, Meng W, Sze SK, Renia L, Preiser P.

Mol Cell Proteomics. 2019 May;18(5):837-853. doi: 10.1074/mcp.RA118.000997. Epub 2019 Feb 4.


Delineation of critical amino acids in activation function 1 of progesterone receptor for recruitment of transcription coregulators.

Woo ARE, Sze SK, Chung HH, Lin VC.

Biochim Biophys Acta Gene Regul Mech. 2019 Apr;1862(4):522-533. doi: 10.1016/j.bbagrm.2019.01.004. Epub 2019 Feb 1.


Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer's disease.

Adav SS, Park JE, Sze SK.

Mol Brain. 2019 Jan 28;12(1):8. doi: 10.1186/s13041-019-0430-y.


Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics.

Kam A, Loo S, Dutta B, Sze SK, Tam JP.

J Biol Chem. 2019 Mar 15;294(11):4000-4011. doi: 10.1074/jbc.RA118.006693. Epub 2019 Jan 23.


Artificially intelligent proteomics improves cardiovascular risk assessment.

Sze SK.

EBioMedicine. 2019 Feb;40:23-24. doi: 10.1016/j.ebiom.2019.01.014. Epub 2019 Jan 14. No abstract available.


Brain-derived and circulating vesicle profiles indicate neurovascular unit dysfunction in early Alzheimer's disease.

Gallart-Palau X, Serra A, Hase Y, Tan CF, Chen CP, Kalaria RN, Sze SK.

Brain Pathol. 2019 Jan 10. doi: 10.1111/bpa.12699. [Epub ahead of print]


Mechanoregulation of cancer-associated fibroblasts phenotype in 3D interpenetrating hydrogel networks.

Cao H, Lee MKH, Yang H, Sze SK, Tan NS, Tay CY.

Langmuir. 2018 Nov 27. doi: 10.1021/acs.langmuir.8b02649. [Epub ahead of print]


Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5.

Shi M, Chen B, Mahajan D, Boh BK, Zhou Y, Dutta B, Tie HC, Sze SK, Wu G, Lu L.

Nat Commun. 2018 Nov 26;9(1):4987. doi: 10.1038/s41467-018-07444-y.


Identification of Arenin, a Novel Kunitz-Like Polypeptide from the Skin Secretions of Dryophytes arenicolor.

Hernández-Pérez J, Serra A, Sze SK, Conway PL, Schlundt J, Benavides J.

Int J Mol Sci. 2018 Nov 19;19(11). pii: E3644. doi: 10.3390/ijms19113644.


Vascular Bed Molecular Profiling by Differential Systemic Decellularization In Vivo.

Serra A, Gallart-Palau X, Park JE, Lim GGY, Lim KL, Ho HH, Tam JP, Sze SK.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2396-2409. doi: 10.1161/ATVBAHA.118.311552.


Bacteria Display Differential Growth and Adhesion Characteristics on Human Hair Shafts.

Kerk SK, Lai HY, Sze SK, Ng KW, Schmidtchen A, Adav SS.

Front Microbiol. 2018 Sep 7;9:2145. doi: 10.3389/fmicb.2018.02145. eCollection 2018.


Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.

Zhang J, Wang J, Zhou Z, Park JE, Wang L, Wu S, Sun X, Lu L, Wang T, Lin Q, Sze SK, Huang D, Shen HM.

Autophagy. 2018;14(6):1043-1059. doi: 10.1080/15548627.2018.1447290. Epub 2018 Jul 30.


Thrombin and Plasmin Alter the Proteome of Neutrophil Extracellular Traps.

Lim CH, Adav SS, Sze SK, Choong YK, Saravanan R, Schmidtchen A.

Front Immunol. 2018 Jul 9;9:1554. doi: 10.3389/fimmu.2018.01554. eCollection 2018.


Author Correction: PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK, Yap CT, Shen HM.

Cell Res. 2018 Aug;28(8):872-873. doi: 10.1038/s41422-018-0068-9.


Molecular diversity and function of jasmintides from Jasminum sambac.

Kumari G, Wong KH, Serra A, Shin J, Yoon HS, Sze SK, Tam JP.

BMC Plant Biol. 2018 Jul 11;18(1):144. doi: 10.1186/s12870-018-1361-y.

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