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Items: 20


Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway.

Newmister SA, Romminger S, Schmidt JJ, Williams RM, Smith JL, Berlinck RGS, Sherman DH.

Org Biomol Chem. 2018 Sep 11;16(35):6450-6459. doi: 10.1039/c8ob01565a.


Structural and stereochemical diversity in prenylated indole alkaloids containing the bicyclo[2.2.2]diazaoctane ring system from marine and terrestrial fungi.

Klas KR, Kato H, Frisvad JC, Yu F, Newmister SA, Fraley AE, Sherman DH, Tsukamoto S, Williams RM.

Nat Prod Rep. 2018 Jun 20;35(6):532-558. doi: 10.1039/c7np00042a. Review.


Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.

Newmister SA, Li S, Garcia-Borràs M, Sanders JN, Yang S, Lowell AN, Yu F, Smith JL, Williams RM, Houk KN, Sherman DH.

Nat Chem Biol. 2018 Apr;14(4):345-351. doi: 10.1038/s41589-018-0003-x. Epub 2018 Mar 12.


Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids.

Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH.

Nat Chem Biol. 2017 May;13(5):467-469. doi: 10.1038/nchembio.2327. Epub 2017 Mar 13.


Crystal Structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase Involved in the Detoxification of Deoxynivalenol.

Wetterhorn KM, Newmister SA, Caniza RK, Busman M, McCormick SP, Berthiller F, Adam G, Rayment I.

Biochemistry. 2016 Nov 8;55(44):6175-6186. Epub 2016 Oct 26.


OxaD: A Versatile Indolic Nitrone Synthase from the Marine-Derived Fungus Penicillium oxalicum F30.

Newmister SA, Gober CM, Romminger S, Yu F, Tripathi A, Parra LL, Williams RM, Berlinck RG, Joullié MM, Sherman DH.

J Am Chem Soc. 2016 Sep 7;138(35):11176-84. doi: 10.1021/jacs.6b04915. Epub 2016 Aug 24.


Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade.

Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH.

J Am Chem Soc. 2015 Dec 16;137(49):15366-9. doi: 10.1021/jacs.5b10136. Epub 2015 Dec 2.


Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside.

Michlmayr H, Malachová A, Varga E, Kleinová J, Lemmens M, Newmister S, Rayment I, Berthiller F, Adam G.

Toxins (Basel). 2015 Jul 21;7(7):2685-700. doi: 10.3390/toxins7072685.


Crystal structures of acyl carrier protein in complex with two catalytic partners show a dynamic role in cellular metabolism.

Newmister SA, Sherman DH.

Chembiochem. 2014 May 26;15(8):1079-81. doi: 10.1002/cbic.201402095. Epub 2014 Apr 25.


Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis.

Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH.

J Am Chem Soc. 2014 Jan 29;136(4):1579-86. doi: 10.1021/ja4115924. Epub 2014 Jan 17. Erratum in: J Am Chem Soc. 2014 Jul 23;136(29):10541.


Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica.

Chan CH, Newmister SA, Talyor K, Claas KR, Rayment I, Escalante-Semerena JC.

Biochim Biophys Acta. 2014 Jan;1840(1):464-75. doi: 10.1016/j.bbagen.2013.09.038. Epub 2013 Oct 10.


Structural insights into the function of the nicotinate mononucleotide:phenol/p-cresol phosphoribosyltransferase (ArsAB) enzyme from Sporomusa ovata.

Newmister SA, Chan CH, Escalante-Semerena JC, Rayment I.

Biochemistry. 2012 Oct 30;51(43):8571-82. doi: 10.1021/bi301142h. Epub 2012 Oct 15.


Structure and mutational analysis of the archaeal GTP:AdoCbi-P guanylyltransferase (CobY) from Methanocaldococcus jannaschii: insights into GTP binding and dimerization.

Newmister SA, Otte MM, Escalante-Semerena JC, Rayment I.

Biochemistry. 2011 Jun 14;50(23):5301-13. doi: 10.1021/bi200329t. Epub 2011 May 18.


Bioprospecting for trichothecene 3-O-acetyltransferases in the fungal genus Fusarium yields functional enzymes with different abilities to modify the mycotoxin deoxynivalenol.

Khatibi PA, Newmister SA, Rayment I, McCormick SP, Alexander NJ, Schmale DG 3rd.

Appl Environ Microbiol. 2011 Feb;77(4):1162-70. doi: 10.1128/AEM.01738-10. Epub 2010 Dec 17.


Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ.

Brown JA, Pack LR, Sherrer SM, Kshetry AK, Newmister SA, Fowler JD, Taylor JS, Suo Z.

J Mol Biol. 2010 Nov 5;403(4):505-15. doi: 10.1016/j.jmb.2010.09.014. Epub 2010 Sep 21.


Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases.

Sherrer SM, Fiala KA, Fowler JD, Newmister SA, Pryor JM, Suo Z.

Nucleic Acids Res. 2011 Jan;39(2):609-22. doi: 10.1093/nar/gkq719. Epub 2010 Sep 15.


A novel mechanism of sugar selection utilized by a human X-family DNA polymerase.

Brown JA, Fiala KA, Fowler JD, Sherrer SM, Newmister SA, Duym WW, Suo Z.

J Mol Biol. 2010 Jan 15;395(2):282-90. doi: 10.1016/j.jmb.2009.11.003. Epub 2009 Nov 6.


Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2.

Zhang L, Brown JA, Newmister SA, Suo Z.

Biochemistry. 2009 Aug 11;48(31):7492-501. doi: 10.1021/bi900532w.


Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase.

Brown JA, Newmister SA, Fiala KA, Suo Z.

Nucleic Acids Res. 2008 Jul;36(12):3867-78. doi: 10.1093/nar/gkn309. Epub 2008 May 22.

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