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Items: 1 to 20 of 24


Moringin from Moringa Oleifera Seeds Inhibits Growth, Arrests Cell-Cycle, and Induces Apoptosis of SH-SY5Y Human Neuroblastoma Cells through the Modulation of NF-κB and Apoptotic Related Factors.

Cirmi S, Ferlazzo N, Gugliandolo A, Musumeci L, Mazzon E, Bramanti A, Navarra M.

Int J Mol Sci. 2019 Apr 19;20(8). pii: E1930. doi: 10.3390/ijms20081930.


Citrus fruits and their flavonoids in inflammatory bowel disease: an overview.

Musumeci L, Maugeri A, Cirmi S, Lombardo GE, Russo C, Gangemi S, Calapai G, Navarra M.

Nat Prod Res. 2019 Apr 16:1-15. doi: 10.1080/14786419.2019.1601196. [Epub ahead of print]


A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137).

Navarra M, Femia AP, Romagnoli A, Tortora K, Luceri C, Cirmi S, Ferlazzo N, Caderni G.

Eur J Nutr. 2019 Mar 27. doi: 10.1007/s00394-019-01948-z. [Epub ahead of print]


Citrus fruits intake and oral cancer risk: A systematic review and meta-analysis.

Cirmi S, Navarra M, Woodside JV, Cantwell MM.

Pharmacol Res. 2018 Jul;133:187-194. doi: 10.1016/j.phrs.2018.05.008. Epub 2018 May 16.


Anticancer Potential of Citrus Juices and Their Extracts: A Systematic Review of Both Preclinical and Clinical Studies.

Cirmi S, Maugeri A, Ferlazzo N, Gangemi S, Calapai G, Schumacher U, Navarra M.

Front Pharmacol. 2017 Jun 30;8:420. doi: 10.3389/fphar.2017.00420. eCollection 2017. Review.


Effectiveness of Citrus Fruits on Helicobacter pylori.

Mandalari G, Bisignano C, Cirmi S, Navarra M.

Evid Based Complement Alternat Med. 2017;2017:8379262. doi: 10.1155/2017/8379262. Epub 2017 Mar 20. Review.


Synthesis of spiro[isoindole-1,5'-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction.

Giofrè SV, Cirmi S, Mancuso R, Nicolò F, Lanza G, Legnani L, Campisi A, Chiacchio MA, Navarra M, Gabriele B, Romeo R.

Beilstein J Org Chem. 2016 Dec 20;12:2793-2807. doi: 10.3762/bjoc.12.278. eCollection 2016.


Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives?

Cirmi S, Ferlazzo N, Lombardo GE, Maugeri A, Calapai G, Gangemi S, Navarra M.

Nutrients. 2016 Nov 4;8(11). pii: E698. Review.


Tunable doxorubicin release from polymer-gated multiwalled carbon nanotubes.

Pistone A, Iannazzo D, Ansari S, Milone C, Salamò M, Galvagno S, Cirmi S, Navarra M.

Int J Pharm. 2016 Dec 30;515(1-2):30-36. doi: 10.1016/j.ijpharm.2016.10.010. Epub 2016 Oct 5.


Mastocytosis and systemic sclerosis: a clinical association.

Bagnato G, Roberts WN, Sciortino D, Sangari D, Cirmi S, Ravenell RL, Navarra M, Bagnato G, Gangemi S.

Clin Mol Allergy. 2016 Oct 11;14:13. eCollection 2016.


Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?

Cirmi S, Ferlazzo N, Lombardo GE, Ventura-Spagnolo E, Gangemi S, Calapai G, Navarra M.

Molecules. 2016 Sep 30;21(10). pii: E1312. Review.


Anti-Inflammatory Activity of Citrus bergamia Derivatives: Where Do We Stand?

Ferlazzo N, Cirmi S, Calapai G, Ventura-Spagnolo E, Gangemi S, Navarra M.

Molecules. 2016 Sep 23;21(10). pii: E1273. doi: 10.3390/molecules21101273. Review.


Anti-infective potential of Citrus bergamia Risso et Poiteau (bergamot) derivatives: a systematic review.

Cirmi S, Bisignano C, Mandalari G, Navarra M.

Phytother Res. 2016 Sep;30(9):1404-11. doi: 10.1002/ptr.5646. Epub 2016 May 24. Review.


Natural iron chelators: Protective role in A549 cells of flavonoids-rich extracts of Citrus juices in Fe(3+)-induced oxidative stress.

Ferlazzo N, Visalli G, Cirmi S, Lombardo GE, Laganà P, Di Pietro A, Navarra M.

Environ Toxicol Pharmacol. 2016 Apr;43:248-56. doi: 10.1016/j.etap.2016.03.005. Epub 2016 Mar 7.


Citrus bergamia Juice Extract Attenuates β-Amyloid-Induced Pro-Inflammatory Activation of THP-1 Cells Through MAPK and AP-1 Pathways.

Currò M, Risitano R, Ferlazzo N, Cirmi S, Gangemi C, Caccamo D, Ientile R, Navarra M.

Sci Rep. 2016 Feb 8;6:20809. doi: 10.1038/srep20809.


NF-κB mediates the antiproliferative and proapoptotic effects of bergamot juice in HepG2 cells.

Ferlazzo N, Cirmi S, Russo M, Trapasso E, Ursino MR, Lombardo GE, Gangemi S, Calapai G, Navarra M.

Life Sci. 2016 Feb 1;146:81-91. doi: 10.1016/j.lfs.2015.12.040. Epub 2016 Jan 5.


Flavonoid Fraction of Orange and Bergamot Juices Protect Human Lung Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Stress.

Ferlazzo N, Visalli G, Smeriglio A, Cirmi S, Lombardo GE, Campiglia P, Di Pietro A, Navarra M.

Evid Based Complement Alternat Med. 2015;2015:957031. doi: 10.1155/2015/957031. Epub 2015 Jun 21.


In vitro effect of bergamot (Citrus bergamia) juice against cagA-positive and-negative clinical isolates of Helicobacter pylori.

Filocamo A, Bisignano C, Ferlazzo N, Cirmi S, Mandalari G, Navarra M.

BMC Complement Altern Med. 2015 Jul 30;15:256. doi: 10.1186/s12906-015-0769-2.


Synthesis and biological properties of 5-(1H-1,2,3-triazol-4-yl)isoxazolidines: a new class of C-nucleosides.

Giofrè SV, Romeo R, Carnovale C, Mancuso R, Cirmi S, Navarra M, Garozzo A, Chiacchio MA.

Molecules. 2015 Mar 24;20(4):5260-75. doi: 10.3390/molecules20045260.


Effects of bergamot essential oil and its extractive fractions on SH-SY5Y human neuroblastoma cell growth.

Navarra M, Ferlazzo N, Cirmi S, Trapasso E, Bramanti P, Lombardo GE, Minciullo PL, Calapai G, Gangemi S.

J Pharm Pharmacol. 2015 Aug;67(8):1042-53. doi: 10.1111/jphp.12403. Epub 2015 Mar 24.


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