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Items: 1 to 20 of 23

1.

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy.

Grubb AL, McDonald TJ, Rutters F, Donnelly LA, Hattersley AT, Oram RA, Palmer CNA, van der Heijden AA, Carr F, Elders PJM, Weedon MN, Slieker RC, 't Hart LM, Pearson ER, Shields BM, Jones AG.

Diabetes Care. 2019 Feb;42(2):208-214. doi: 10.2337/dc18-0431. Epub 2018 Oct 23.

PMID:
30352895
2.

Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes.

't Hart LM, Vogelzangs N, Mook-Kanamori DO, Brahimaj A, Nano J, van der Heijden AAWA, Willems van Dijk K, Slieker RC, Steyerberg EW, Ikram MA, Beekman M, Boomsma DI, van Duijn CM, Slagboom PE, Stehouwer CDA, Schalkwijk CG, Arts ICW, Dekker JM, Dehghan A, Muka T, van der Kallen CJH, Nijpels G, van Greevenbroek MMJ.

J Clin Endocrinol Metab. 2018 Dec 1;103(12):4569-4579. doi: 10.1210/jc.2018-01165.

PMID:
30113659
3.

Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception.

Slieker RC, Relton CL, Gaunt TR, Slagboom PE, Heijmans BT.

Epigenetics Chromatin. 2018 May 30;11(1):25. doi: 10.1186/s13072-018-0191-3.

4.

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood.

Tobi EW, Slieker RC, Luijk R, Dekkers KF, Stein AD, Xu KM; Biobank-based Integrative Omics Studies Consortium, Slagboom PE, van Zwet EW, Lumey LH, Heijmans BT.

Sci Adv. 2018 Jan 31;4(1):eaao4364. doi: 10.1126/sciadv.aao4364. eCollection 2018 Jan.

5.

A SNP panel for identification of DNA and RNA specimens.

Yousefi S, Abbassi-Daloii T, Kraaijenbrink T, Vermaat M, Mei H, van 't Hof P, van Iterson M, Zhernakova DV, Claringbould A, Franke L, 't Hart LM, Slieker RC, van der Heijden A, de Knijff P; BIOS consortium, 't Hoen PAC.

BMC Genomics. 2018 Jan 25;19(1):90. doi: 10.1186/s12864-018-4482-7.

6.

HbA1c is associated with altered expression in blood of cell cycle- and immune response-related genes.

Slieker RC, van der Heijden AAWA, van Leeuwen N, Mei H, Nijpels G, Beulens JWJ, 't Hart LM.

Diabetologia. 2018 Jan;61(1):138-146. doi: 10.1007/s00125-017-4467-0. Epub 2017 Nov 20.

7.

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.

Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM.

Nat Commun. 2017 Oct 13;8(1):908. doi: 10.1038/s41467-017-01077-3.

8.

Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn.

Herzog EM, Eggink AJ, Willemsen SP, Slieker RC, Wijnands KPJ, Felix JF, Chen J, Stubbs A, van der Spek PJ, van Meurs JB, Steegers-Theunissen RPM.

Placenta. 2017 Oct;58:122-132. doi: 10.1016/j.placenta.2017.08.070. Epub 2017 Aug 30.

9.

SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes.

Mason AG, Slieker RC, Balog J, Lemmers RJLF, Wong CJ, Yao Z, Lim JW, Filippova GN, Ne E, Tawil R, Heijmans BT, Tapscott SJ, van der Maarel SM.

Skelet Muscle. 2017 Jun 6;7(1):12. doi: 10.1186/s13395-017-0129-7.

10.

Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice.

Zwamborn RA, Slieker RC, Mulder PC, Zoetemelk I, Verschuren L, Suchiman HE, Toet KH, Droog S, Slagboom PE, Kooistra T, Kleemann R, Heijmans BT.

Sci Rep. 2017 Mar 3;7:43261. doi: 10.1038/srep43261.

11.

Disease variants alter transcription factor levels and methylation of their binding sites.

Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT.

Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5.

PMID:
27918535
12.

Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms.

Slieker RC, van Iterson M, Luijk R, Beekman M, Zhernakova DV, Moed MH, Mei H, van Galen M, Deelen P, Bonder MJ, Zhernakova A, Uitterlinden AG, Tigchelaar EF, Stehouwer CD, Schalkwijk CG, van der Kallen CJ, Hofman A, van Heemst D, de Geus EJ, van Dongen J, Deelen J, van den Berg LH, van Meurs J, Jansen R, 't Hoen PA, Franke L, Wijmenga C, Veldink JH, Swertz MA, van Greevenbroek MM, van Duijn CM, Boomsma DI; BIOS consortium, Slagboom PE, Heijmans BT.

Genome Biol. 2016 Sep 22;17(1):191.

13.

Blood lipids influence DNA methylation in circulating cells.

Dekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, Mei H, Zhernakova DV, van den Berg LH, Deelen J, van Dongen J, van Heemst D, Hofman A, Hottenga JJ, van der Kallen CJ, Schalkwijk CG, Stehouwer CD, Tigchelaar EF, Uitterlinden AG, Willemsen G, Zhernakova A, Franke L, 't Hoen PA, Jansen R, van Meurs J, Boomsma DI, van Duijn CM, van Greevenbroek MM, Veldink JH, Wijmenga C; BIOS Consortium, van Zwet EW, Slagboom PE, Jukema JW, Heijmans BT.

Genome Biol. 2016 Jun 27;17(1):138. doi: 10.1186/s13059-016-1000-6.

14.

Epigenomic Analysis of Sézary Syndrome Defines Patterns of Aberrant DNA Methylation and Identifies Diagnostic Markers.

van Doorn R, Slieker RC, Boonk SE, Zoutman WH, Goeman JJ, Bagot M, Michel L, Tensen CP, Willemze R, Heijmans BT, Vermeer MH.

J Invest Dermatol. 2016 Sep;136(9):1876-1884. doi: 10.1016/j.jid.2016.03.042. Epub 2016 Apr 23. Review.

15.

DNA Methylation Landscapes of Human Fetal Development.

Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT, Chuva de Sousa Lopes SM.

PLoS Genet. 2015 Oct 22;11(10):e1005583. doi: 10.1371/journal.pgen.1005583. eCollection 2015 Oct.

16.

Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER.

Suchiman HE, Slieker RC, Kremer D, Slagboom PE, Heijmans BT, Tobi EW.

Front Genet. 2015 Sep 17;6:287. doi: 10.3389/fgene.2015.00287. eCollection 2015.

17.

Corrigendum: DNA methylation signatures link prenatal famine exposure to growth and metabolism.

Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, Heijmans BT.

Nat Commun. 2015 Jul 7;6:7740. doi: 10.1038/ncomms8740. No abstract available.

18.

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells.

Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker RC, Heijmans BT, Deforce D, De Sutter P, De Sousa Lopes SC, Heindryckx B.

Stem Cells. 2015 Sep;33(9):2686-98. doi: 10.1002/stem.2071. Epub 2015 Jun 24.

19.

Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome.

Tobi EW, Slieker RC, Stein AD, Suchiman HE, Slagboom PE, van Zwet EW, Heijmans BT, Lumey LH.

Int J Epidemiol. 2015 Aug;44(4):1211-23. doi: 10.1093/ije/dyv043. Epub 2015 May 5.

20.

DNA methylation signatures link prenatal famine exposure to growth and metabolism.

Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, Heijmans BT.

Nat Commun. 2014 Nov 26;5:5592. doi: 10.1038/ncomms6592. Erratum in: Nat Commun. 2015;6:7740.

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