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Items: 1 to 20 of 35

1.

Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis.

Jalan-Sakrikar N, M De Assuncao T, Shi G, Aseem S, Cheng C, Shah VH, Huebert RC.

Hepatology. 2019 May 9. doi: 10.1002/hep.30706. [Epub ahead of print]

PMID:
31070797
2.

Cholangiocyte pathobiology.

Banales JM, Huebert RC, Karlsen T, Strazzabosco M, LaRusso NF, Gores GJ.

Nat Rev Gastroenterol Hepatol. 2019 May;16(5):269-281. doi: 10.1038/s41575-019-0125-y. Review.

PMID:
30850822
3.

3D Printing for Bio-Synthetic Biliary Stents.

Boyer CJ, Boktor M, Samant H, White LA, Wang Y, Ballard DH, Huebert RC, Woerner JE, Ghali GE, Alexander JS.

Bioengineering (Basel). 2019 Feb 9;6(1). pii: E16. doi: 10.3390/bioengineering6010016.

4.

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis.

Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH.

Cell Mol Gastroenterol Hepatol. 2019;7(1):197-209. doi: 10.1016/j.jcmgh.2018.09.005. Epub 2018 Sep 15.

5.

Ducts in a dish: Bioengineered biliary scaffolds for regenerative medicine.

Jalan-Sakrikar N, Huebert RC.

Hepatology. 2018 Apr;67(4):1622-1624. doi: 10.1002/hep.29614. Epub 2018 Feb 18. No abstract available.

PMID:
29059474
6.

Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis.

Loarca L, De Assuncao TM, Jalan-Sakrikar N, Bronk S, Krishnan A, Huang B, Morton L, Trussoni C, Bonilla LM, Krueger E, O'Hara S, Splinter P, Shi G, Pisarello MJL, Gores GJ, Huebert RC, LaRusso NF.

Lab Invest. 2017 Nov;97(11):1385-1396. doi: 10.1038/labinvest.2017.63. Epub 2017 Sep 11.

7.

SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma.

Merino-Azpitarte M, Lozano E, Perugorria MJ, Esparza-Baquer A, Erice O, Santos-Laso Á, O'Rourke CJ, Andersen JB, Jiménez-Agüero R, Lacasta A, D'Amato M, Briz Ó, Jalan-Sakrikar N, Huebert RC, Thelen KM, Gradilone SA, Aransay AM, Lavín JL, Fernández-Barrena MG, Matheu A, Marzioni M, Gores GJ, Bujanda L, Marin JJG, Banales JM.

J Hepatol. 2017 Jul;67(1):72-83. doi: 10.1016/j.jhep.2017.02.017. Epub 2017 Feb 22.

8.

Regenerative Medicine and the Biliary Tree.

De Assuncao TM, Jalan-Sakrikar N, Huebert RC.

Semin Liver Dis. 2017 Feb;37(1):17-27. doi: 10.1055/s-0036-1597818. Epub 2017 Feb 15. Review.

9.

The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice.

Maiers JL, Kostallari E, Mushref M, deAssuncao TM, Li H, Jalan-Sakrikar N, Huebert RC, Cao S, Malhi H, Shah VH.

Hepatology. 2017 Mar;65(3):983-998. doi: 10.1002/hep.28921. Epub 2016 Dec 31.

10.

Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion.

Jalan-Sakrikar N, De Assuncao TM, Lu J, Almada LL, Lomberk G, Fernandez-Zapico ME, Urrutia R, Huebert RC.

PLoS One. 2016 Dec 9;11(12):e0168266. doi: 10.1371/journal.pone.0168266. eCollection 2016.

11.

Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration.

Wang R, Ding Q, De Assuncao TM, Mounajjed T, Maiers JL, Dou C, Cao S, Yaqoob U, Huebert RC, Shah VH.

Am J Pathol. 2017 Jan;187(1):134-145. doi: 10.1016/j.ajpath.2016.09.001. Epub 2016 Nov 10.

12.

Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy.

Lu J, Zhou Y, Hu T, Zhang H, Shen M, Cheng P, Dai W, Wang F, Chen K, Zhang Y, Wang C, Li J, Zheng Y, Yang J, Zhu R, Wang J, Lu W, Zhang H, Wang J, Xia Y, De Assuncao TM, Jalan-Sakrikar N, Huebert RC, Bin Zhou, Guo C.

Sci Rep. 2016 Mar 8;6:22754. doi: 10.1038/srep22754.

13.

Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration.

Wang R, Ding Q, Yaqoob U, de Assuncao TM, Verma VK, Hirsova P, Cao S, Mukhopadhyay D, Huebert RC, Shah VH.

J Biol Chem. 2015 Dec 25;290(52):30684-96. doi: 10.1074/jbc.M115.671735. Epub 2015 Nov 3.

14.

Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes.

De Assuncao TM, Sun Y, Jalan-Sakrikar N, Drinane MC, Huang BQ, Li Y, Davila JI, Wang R, O'Hara SP, Lomberk GA, Urrutia RA, Ikeda Y, Huebert RC.

Lab Invest. 2015 Oct;95(10):1218. doi: 10.1038/labinvest.2015.99. No abstract available.

15.

Black and White Liver.

Helmick RA, McMenomy BP, Huebert RC.

Clin Gastroenterol Hepatol. 2016 Jan;14(1):A39-40. doi: 10.1016/j.cgh.2015.09.006. Epub 2015 Sep 15. No abstract available.

PMID:
26385443
16.

Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes.

De Assuncao TM, Sun Y, Jalan-Sakrikar N, Drinane MC, Huang BQ, Li Y, Davila JI, Wang R, O'Hara SP, Lomberk GA, Urrutia RA, Ikeda Y, Huebert RC.

Lab Invest. 2015 Jun;95(6):684-96. doi: 10.1038/labinvest.2015.51. Epub 2015 Apr 13. Erratum in: Lab Invest. 2015 Oct;95(10):1218.

17.

Sinusoidal endothelial cells coordinate liver regeneration and angiogenesis via angiopoietin-2: an ode to prometheus.

Wang R, Huebert RC, Shah VH.

Gastroenterology. 2014 Aug;147(2):533-4. doi: 10.1053/j.gastro.2014.06.015. Epub 2014 Jun 21. No abstract available.

PMID:
24960616
18.

New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids.

de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH.

J Biol Chem. 2014 May 30;289(22):15798-809. doi: 10.1074/jbc.M113.544346. Epub 2014 Apr 23.

19.

Sinusoidal endothelial cells direct traffic at the intersection of regeneration and fibrosis.

Huebert RC, Shah VH.

Hepatology. 2014 Aug;60(2):754-6. doi: 10.1002/hep.27116. Epub 2014 May 6. No abstract available.

20.

Cellular therapy for liver disease.

Huebert RC, Rakela J.

Mayo Clin Proc. 2014 Mar;89(3):414-24. doi: 10.1016/j.mayocp.2013.10.023. Review.

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