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Items: 1 to 20 of 25

1.

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.

Romeo G, Prezzavento O, Intagliata S, Pittalà V, Modica MN, Marrazzo A, Turnaturi R, Parenti C, Chiechio S, Arena E, Campisi A, Sposito G, Salerno L.

Eur J Med Chem. 2019 Jul 15;174:226-235. doi: 10.1016/j.ejmech.2019.04.056. Epub 2019 Apr 21.

PMID:
31042618
2.

Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain.

Vicario N, Pasquinucci L, Spitale FM, Chiechio S, Turnaturi R, Caraci F, Tibullo D, Avola R, Gulino R, Parenti R, Parenti C.

Mol Neurobiol. 2019 Apr 28. doi: 10.1007/s12035-019-1607-1. [Epub ahead of print]

PMID:
31030416
3.

Neuroprotective effects of Rosmarinus officinalis L. extract in oxygen glucose deprivation (OGD)-injured human neural-like cells.

Zappalà A, Vicario N, Calabrese G, Turnaturi R, Pasquinucci L, Montenegro L, Spadaro A, Parenti R, Parenti C.

Nat Prod Res. 2019 Apr 2:1-7. doi: 10.1080/14786419.2019.1587428. [Epub ahead of print]

PMID:
30938188
4.

(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist.

Pasquinucci L, Turnaturi R, Calò G, Pappalardo F, Ferrari F, Russo G, Arena E, Montenegro L, Chiechio S, Prezzavento O, Parenti C.

Eur J Med Chem. 2019 Apr 15;168:189-198. doi: 10.1016/j.ejmech.2019.02.043. Epub 2019 Feb 18.

PMID:
30822708
5.

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application.

Salerno L, Floresta G, Ciaffaglione V, Gentile D, Margani F, Turnaturi R, Rescifina A, Pittalà V.

Eur J Med Chem. 2019 Apr 1;167:439-453. doi: 10.1016/j.ejmech.2019.02.027. Epub 2019 Feb 12. Review.

PMID:
30784878
6.

Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation.

Pasquinucci L, Turnaturi R, Montenegro L, Caraci F, Chiechio S, Parenti C.

Eur J Pharmacol. 2019 Mar 15;847:97-102. doi: 10.1016/j.ejphar.2019.01.031. Epub 2019 Jan 25.

PMID:
30690004
7.

A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands.

Floresta G, Amata E, Barbaraci C, Gentile D, Turnaturi R, Marrazzo A, Rescifina A.

Mar Drugs. 2018 Oct 14;16(10). pii: E384. doi: 10.3390/md16100384.

8.

Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.

Sorrenti V, Pittalà V, Romeo G, Amata E, Dichiara M, Marrazzo A, Turnaturi R, Prezzavento O, Barbagallo I, Vanella L, Rescifina A, Floresta G, Tibullo D, Di Raimondo F, Intagliata S, Salerno L.

Eur J Med Chem. 2018 Oct 5;158:937-950. doi: 10.1016/j.ejmech.2018.09.048. Epub 2018 Sep 17.

PMID:
30261468
9.

Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review.

Turnaturi R, Montenegro L, Marrazzo A, Parenti R, Pasquinucci L, Parenti C.

Eur J Med Chem. 2018 Jul 15;155:492-502. doi: 10.1016/j.ejmech.2018.06.017. Epub 2018 Jun 7. Review.

PMID:
29908442
10.

Synthesis and Structure-Activity Relationships of (-)-cis-N-Normetazocine-Based LP1 Derivatives.

Pasquinucci L, Parenti C, Amata E, Georgoussi Z, Pallaki P, Camarda V, Calò G, Arena E, Montenegro L, Turnaturi R.

Pharmaceuticals (Basel). 2018 May 5;11(2). pii: E40. doi: 10.3390/ph11020040.

11.

Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists.

Turnaturi R, Parenti C, Prezzavento O, Marrazzo A, Pallaki P, Georgoussi Z, Amata E, Pasquinucci L.

Molecules. 2018 Mar 16;23(3). pii: E677. doi: 10.3390/molecules23030677.

12.

In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations.

Montenegro L, Turnaturi R, Parenti C, Pasquinucci L.

Pharmaceutics. 2018 Feb 27;10(1). pii: E27. doi: 10.3390/pharmaceutics10010027.

13.

Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review.

Turnaturi R, Marrazzo A, Parenti C, Pasquinucci L.

Eur J Med Chem. 2018 Mar 25;148:410-422. doi: 10.1016/j.ejmech.2018.02.046. Epub 2018 Feb 17. Review.

PMID:
29477074
14.

Idebenone: Novel Strategies to Improve Its Systemic and Local Efficacy.

Montenegro L, Turnaturi R, Parenti C, Pasquinucci L.

Nanomaterials (Basel). 2018 Feb 5;8(2). pii: E87. doi: 10.3390/nano8020087. Review.

15.

Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.

Montenegro L, Parenti C, Turnaturi R, Pasquinucci L.

Pharmaceutics. 2017 Dec 10;9(4). pii: E58. doi: 10.3390/pharmaceutics9040058.

16.

Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles.

Montenegro L, Pasquinucci L, Zappalà A, Chiechio S, Turnaturi R, Parenti C.

Pharmaceutics. 2017 Oct 21;9(4). pii: E48. doi: 10.3390/pharmaceutics9040048.

17.

Development of novel LP1-based analogues with enhanced delta opioid receptor profile.

Pasquinucci L, Turnaturi R, Prezzavento O, Arena E, Aricò G, Georgoussi Z, Parenti R, Cantarella G, Parenti C.

Bioorg Med Chem. 2017 Sep 1;25(17):4745-4752. doi: 10.1016/j.bmc.2017.07.021. Epub 2017 Jul 11.

PMID:
28734666
18.

Multitarget Opioid/Non-opioid Ligands: A Potential Approach in Pain Management.

Turnaturi R, Arico G, Ronsisvalle G, Pasquinucci L, Parenti C.

Curr Med Chem. 2016;23(40):4506-4528. Review.

PMID:
27781944
19.

Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect.

Vicario N, Parenti R, Arico' G, Turnaturi R, Scoto GM, Chiechio S, Parenti C.

Mol Pain. 2016 Sep 2;12. pii: 1744806916667949. doi: 10.1177/1744806916667949. Print 2016. No abstract available.

20.

Evaluation of N-substituent structural variations in opioid receptor profile of LP1.

Pasquinucci L, Turnaturi R, Aricò G, Parenti C, Pallaki P, Georgoussi Z, Ronsisvalle S.

Bioorg Med Chem. 2016 Jun 15;24(12):2832-42. doi: 10.1016/j.bmc.2016.05.005. Epub 2016 May 5.

PMID:
27234885

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