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Items: 20

1.

Possibility of [1,5] sigmatropic shifts in bicyclo[4.2.0]octa-2,4-dienes.

Goossens H, Winne JM, Wouters S, Hermosilla L, De Clercq PJ, Waroquier M, Van Speybroeck V, Catak S.

J Org Chem. 2015 Mar 6;80(5):2609-20. doi: 10.1021/jo5027639. Epub 2015 Feb 12.

PMID:
25615563
2.

Synthesis of 1alpha,25-dihydroxyvitamin D analogues featuring a S(2)-symmetric CD-ring core.

Minne G, Verlinden L, Verstuyf A, De Clercq PJ.

Molecules. 2009 Feb 24;14(2):894-903. doi: 10.3390/molecules14020894.

3.

Nonenzymic polycyclization of analogues of oxidosqualene with a preformed C-ring.

Winne JM, De Clercq PJ, Milanesio M, Pattison P, Viterbo D.

Org Biomol Chem. 2008 Jun 7;6(11):1918-25. doi: 10.1039/b801670d. Epub 2008 Apr 8.

PMID:
18480904
4.
5.
6.

Asymmetric synthesis of the epimeric (3S)-3-((E)-hex-1-enyl)-2-methylcyclohexanones.

Vrielynck FA, De Clercq PJ.

Molecules. 2007 Feb 21;12(2):237-44.

7.

Synthesis of 3,4,7,8-tetrahydronaphthalene-1,5(2H,6H)-dione.

Minne GB, De Clercq PJ.

Molecules. 2007 Feb 13;12(2):183-7.

8.

The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D.

De Clercq PJ, De Buysser F, Minne G, Schepens W, Vrielynck F, Van Haver D, Vandewalle M, Verstuyf A, Bouillon R.

J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):206-12. Epub 2007 Jan 10.

PMID:
17218098
9.
10.

Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3.

Schepens W, Van Haver D, Vandewalle M, Bouillon R, Verstuyf A, De Clercq PJ.

Org Lett. 2006 Sep 14;8(19):4247-50.

PMID:
16956198
11.

Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1alpha,25-dihydroxyvitamin D analogs.

De Clercq PJ, Murad I, Gao LJ, Chen YJ, Van Haver D, Vandewalle M, Verstuyf A, Verlinden L, Verboven C, Bouillon R.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):61-6.

PMID:
15225748
12.

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues.

Schepens W, Van Haver DV, Vandewalle M, De Clercq PJ, Bouillon R, Verstuyf A.

Bioorg Med Chem Lett. 2004 Aug 2;14(15):3889-92.

PMID:
15225691
13.

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues.

Demin S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R, Verstuyf A.

Bioorg Med Chem Lett. 2004 Aug 2;14(15):3885-8.

PMID:
15225690
14.

Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs.

Chen YJ, Gao LJ, Murad I, Verstuyf A, Verlinden L, Verboven C, Bouillon R, Viterbo D, Milanesio M, Van Haver D, Vandewalle M, De Clercq PJ.

Org Biomol Chem. 2003 Jan 21;1(2):257-67.

PMID:
12929421
15.

Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.

Verlinden L, Verstuyf A, Verboven C, Eelen G, De Ranter C, Gao LJ, Chen YJ, Murad I, Choi M, Yamamoto K, Yamada S, Van Haver D, Vandewalle M, De Clercq PJ, Bouillon R.

J Biol Chem. 2003 Sep 12;278(37):35476-82. Epub 2003 Jun 26.

16.

Evaluation of a two-stage screening procedure in the combinatorial search for serine protease-like activity.

Madder A, Li L, De Muynck H, Farcy N, Van Haver D, Fant F, Vanhoenacker G, Sandra P, Davis AP, De Clercq PJ.

J Comb Chem. 2002 Nov-Dec;4(6):552-62.

PMID:
12425599
17.

Synthesis and affinity studies of himbacine derived muscarinic receptor antagonists.

Gao LJ, Waelbroeck M, Hofman S, Van Haver D, Milanesio M, Viterbo D, De Clercq PJ.

Bioorg Med Chem Lett. 2002 Aug 5;12(15):1909-12.

PMID:
12113806
18.

A novel short convergent entry into himbacine derivatives.

Van Cauwenberge G, Gao LJ, Van Haver D, Milanesio M, Viterbo D, De Clercq PJ.

Org Lett. 2002 May 2;4(9):1579-82.

PMID:
11975633
19.

Biotin: A Timeless Challenge for Total Synthesis.

De Clercq PJ.

Chem Rev. 1997 Oct 1;97(6):1755-1792. No abstract available.

PMID:
11848892
20.

Stepwise Approach toward First Generation Nonenzymatic Hydrolases.

Madder A, De Clercq PJ, Declercq JP.

J Org Chem. 1998 Apr 17;63(8):2548-2559.

PMID:
11672118

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