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Low HIF-1α and low EGFR mRNA Expression Significantly Associate with Poor Survival in Soft Tissue Sarcoma Patients; the Proteins React Differently.

Rot S, Taubert H, Bache M, Greither T, Würl P, Holzhausen HJ, Eckert AW, Vordermark D, Kappler M.

Int J Mol Sci. 2018 Dec 3;19(12). pii: E3842. doi: 10.3390/ijms19123842.


Elevated HERV-K Expression in Soft Tissue Sarcoma Is Associated with Worsened Relapse-Free Survival.

Giebler M, Staege MS, Blauschmidt S, Ohm LI, Kraus M, Würl P, Taubert H, Greither T.

Front Microbiol. 2018 Feb 13;9:211. doi: 10.3389/fmicb.2018.00211. eCollection 2018.


CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients.

Greither T, Wedler A, Rot S, Keßler J, Kehlen A, Holzhausen HJ, Bache M, Würl P, Taubert H, Kappler M.

Int J Mol Sci. 2017 Dec 7;18(12). pii: E2648. doi: 10.3390/ijms18122648.


miR-199a-5p regulates HIF-1α and OSGIN2 and its expression is correlated to soft-tissue sarcoma patients' outcome.

Keßler J, Rot S, Bache M, Kappler M, Würl P, Vordermark D, Taubert H, Greither T.

Oncol Lett. 2016 Dec;12(6):5281-5288. doi: 10.3892/ol.2016.5320. Epub 2016 Oct 26.


CD44 SNPrs187115: A Novel Biomarker Signature that Predicts Survival in Resectable Pancreatic Ductal Adenocarcinoma.

Stracquadanio G, Vrugt B, Flury R, Schraml P, Würl P, Müller TH, Knippschild U, Henne-Bruns D, Breitenstein S, Clavien PA, Graf R, Bond GL, Grochola LF.

Clin Cancer Res. 2016 Dec 15;22(24):6069-6077. Epub 2016 Jun 9.


MDM2 SNP 309G Allele Is Associated With Younger Age at Surgery in Chronic Pancreatitis Patients.

Udelnow A, Henne-Bruns D, Knippschild U, Halangk W, Bruns C, Halloul Z, Würl P, Grochola LF.

Pancreas. 2016 Apr;45(4):e11-2. doi: 10.1097/MPA.0000000000000602. No abstract available.


Expression of the LIM homeobox domain transcription factor ISL1 (Islet-1) is frequent in rhabdomyosarcoma but very limited in other soft tissue sarcoma types.

Erlenbach-Wünsch K, Haller F, Taubert H, Würl P, Hartmann A, Agaimy A.

Pathology. 2014 Jun;46(4):289-95. doi: 10.1097/PAT.0000000000000091.


Inverse prognostic impact of ErbB2 mRNA and protein expression level in tumors of soft tissue sarcoma patients.

Wichmann H, Güttler A, Bache M, Taubert H, Vetter M, Würl P, Holzhausen HJ, Eckert AW, Kappler M, Vordermark D.

Strahlenther Onkol. 2014 Oct;190(10):912-8. doi: 10.1007/s00066-014-0655-8. Epub 2014 Apr 9.


High coexpression of CCL2 and CX3CL1 is gender-specifically associated with good prognosis in soft tissue sarcoma patients.

Kehlen A, Greither T, Wach S, Nolte E, Kappler M, Bache M, Holzhausen HJ, Lautenschläger C, Göbel S, Würl P, Immel UD, Agaimy A, Wullich B, Taubert H.

Int J Cancer. 2014 Nov 1;135(9):2096-106. doi: 10.1002/ijc.28867. Epub 2014 Apr 4.


In vitro chemo-sensitivity assay guided chemotherapy is associated with prolonged overall survival in cancer patients.

Udelnow A, Schönfęlder M, Würl P, Halloul Z, Meyer F, Lippert H, Mroczkowski P.

Pol Przegl Chir. 2013 Jun;85(6):340-7. doi: 10.2478/pjs-2013-0051.


Two-center observational study of the accuracy of a Bayes Network for short-term outcome prediction in cholecystectomy patients.

Udelnow A, Schmidt A, Muche R, Henne-Bruns D, Würl P, Lippert H.

Dig Surg. 2013;30(1):28-34. doi: 10.1159/000348670. Epub 2013 Apr 16.


Expression of human Piwi-like genes is associated with prognosis for soft tissue sarcoma patients.

Greither T, Koser F, Kappler M, Bache M, Lautenschläger C, Göbel S, Holzhausen HJ, Wach S, Würl P, Taubert H.

BMC Cancer. 2012 Jun 29;12:272. doi: 10.1186/1471-2407-12-272.


Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients.

Hahnel A, Wichmann H, Greither T, Kappler M, Würl P, Kotzsch M, Taubert H, Vordermark D, Bache M.

BMC Cancer. 2012 Apr 2;12:131. doi: 10.1186/1471-2407-12-131.


A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.

Yee KS, Grochola L, Hamilton G, Grawenda A, Bond EE, Taubert H, Wurl P, Bond GL, O'Neill E.

Cancer Res. 2012 May 1;72(9):2206-17. doi: 10.1158/0008-5472.CAN-11-2906. Epub 2012 Mar 2.


A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients.

Rot S, Taubert H, Bache M, Greither T, Würl P, Eckert AW, Schubert J, Vordermark D, Kappler M.

BMC Cancer. 2011 Oct 6;11:429. doi: 10.1186/1471-2407-11-429.


Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients.

Kotzsch M, Magdolen V, Greither T, Kappler M, Bache M, Lautenschläger C, Füssel S, Eckert AW, Luther T, Baretton G, Würl P, Taubert H.

BMC Cancer. 2011 Jun 25;11:273. doi: 10.1186/1471-2407-11-273.


Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells.

Udelnow A, Kreyes A, Ellinger S, Landfester K, Walther P, Klapperstueck T, Wohlrab J, Henne-Bruns D, Knippschild U, Würl P.

PLoS One. 2011;6(5):e20143. doi: 10.1371/journal.pone.0020143. Epub 2011 May 24.


Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients.

Bache M, Kappler M, Wichmann H, Rot S, Hahnel A, Greither T, Said HM, Kotzsch M, Würl P, Taubert H, Vordermark D.

BMC Cancer. 2010 Apr 8;10:132. doi: 10.1186/1471-2407-10-132.


Expression of survivin detected by immunohistochemistry in the cytoplasm and in the nucleus is associated with prognosis of leiomyosarcoma and synovial sarcoma patients.

Taubert H, Heidenreich C, Holzhausen HJ, Schulz A, Bache M, Kappler M, Eckert AW, Würl P, Melcher I, Hauptmann K, Hauptmann S, Schaser KD.

BMC Cancer. 2010 Feb 24;10:65. doi: 10.1186/1471-2407-10-65.

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