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Items: 1 to 20 of 108


Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.

Jacobsen JPR, Oh A, Bangle R, Roberts WL, Royer EL, Modesto N, Windermere SA, Yi Z, Vernon R, Cajina M, Urs NM, Snyder JC, Nicholls PJ, Sachs BD, Caron MG.

Neuropsychopharmacology. 2019 Apr 29. doi: 10.1038/s41386-019-0400-1. [Epub ahead of print]


Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.

Nicholls PK, Bellott DW, Cho TJ, Pyntikova T, Page DC.

G3 (Bethesda). 2019 May 7;9(5):1481-1486. doi: 10.1534/g3.119.300582.


Mechanisms of neuroprotection against ischemic insult by stress-inducible phosphoprotein-1/prion protein complex.

Beraldo FH, Ostapchenko VG, Xu JZ, Di Guglielmo GM, Fan J, Nicholls PJ, Caron MG, Prado VF, Prado MAM.

J Neurochem. 2018 Apr;145(1):68-79. doi: 10.1111/jnc.14281. Epub 2018 Jan 12.


Effectiveness of 32 versus 20 weeks of prednisolone in leprosy patients with recent nerve function impairment: A randomized controlled trial.

Wagenaar I, Post E, Brandsma W, Bowers B, Alam K, Shetty V, Pai V, Husain S, Sigit Prakoeswa CR, Astari L, Hagge D, Shah M, Neupane K, Tamang KB; TENLEP study group, Nicholls P, Richardus JH.

PLoS Negl Trop Dis. 2017 Oct 4;11(10):e0005952. doi: 10.1371/journal.pntd.0005952. eCollection 2017 Oct.


Opening a Can of Worms: Leprosy Reactions and Complicit Soil-Transmitted Helminths.

Hagge DA, Parajuli P, Kunwar CB, Rana DRSJB, Thapa R, Neupane KD, Nicholls P, Adams LB, Geluk A, Shah M, Napit IB.

EBioMedicine. 2017 Sep;23:119-124. doi: 10.1016/j.ebiom.2017.08.026. Epub 2017 Sep 1.


A leprosy clinical severity scale for erythema nodosum leprosum: An international, multicentre validation study of the ENLIST ENL Severity Scale.

Walker SL, Sales AM, Butlin CR, Shah M, Maghanoy A, Lambert SM, Darlong J, Rozario BJ, Pai VV, Balagon M, Doni SN, Hagge DA, Nery JAC, Neupane KD, Baral S, Sangma BA, Alembo DT, Yetaye AM, Hassan BA, Shelemo MB, Nicholls PG, Lockwood DNJ; Erythema Nodosum Leprosum International STudy Group.

PLoS Negl Trop Dis. 2017 Jul 3;11(7):e0005716. doi: 10.1371/journal.pntd.0005716. eCollection 2017 Jul.


Perceived Health Benefits and Willingness to Pay for Parks by Park Users: Quantitative and Qualitative Research.

Henderson-Wilson C, Sia KL, Veitch J, Staiger PK, Davidson P, Nicholls P.

Int J Environ Res Public Health. 2017 May 15;14(5). pii: E529. doi: 10.3390/ijerph14050529.


Outcome of 6 months MBMDT in MB patients in Bangladesh- preliminary results.

Butlin CR, Pahan D, Maug AKJ, Withington S, Nicholls P, Alam K, Salim MDAH.

Lepr Rev. 2016 Jun;87(2):171-82.


Corticosteroids for treating nerve damage in leprosy.

Van Veen NH, Nicholls PG, Smith WC, Richardus JH.

Cochrane Database Syst Rev. 2016 May 23;(5):CD005491. doi: 10.1002/14651858.CD005491.pub3. Review.


A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.

Kern DM, Nicholls PK, Page DC, Cheeseman IM.

J Cell Biol. 2016 May 9;213(3):315-28. doi: 10.1083/jcb.201510117. Epub 2016 May 2.


Comparison of Efficacy and Safety of Ciclosporin to Prednisolone in the Treatment of Erythema Nodosum Leprosum: Two Randomised, Double Blind, Controlled Pilot Studies in Ethiopia.

Lambert SM, Nigusse SD, Alembo DT, Walker SL, Nicholls PG, Idriss MH, Yamuah LK, Lockwood DN.

PLoS Negl Trop Dis. 2016 Feb 26;10(2):e0004149. doi: 10.1371/journal.pntd.0004149. eCollection 2016 Feb.


Suppression of Sertoli cell tumour development during the first wave of spermatogenesis in inhibin α-deficient mice.

Haverfield JT, Stanton PG, Loveland KL, Zahid H, Nicholls PK, Olcorn JS, Makanji Y, Itman CM, Simpson ER, Meachem SJ.

Reprod Fertil Dev. 2017 Mar;29(3):609-620. doi: 10.1071/RD15239.


ENLIST 1: An International Multi-centre Cross-sectional Study of the Clinical Features of Erythema Nodosum Leprosum.

Walker SL, Balagon M, Darlong J, Doni SN, Hagge DA, Halwai V, John A, Lambert SM, Maghanoy A, Nery JA, Neupane KD, Nicholls PG, Pai VV, Parajuli P, Sales AM, Sarno E, Shah M, Tsegaye D, Lockwood DN; Erythema Nodosum Leprosum International STudy Group.

PLoS Negl Trop Dis. 2015 Sep 9;9(9):e0004065. doi: 10.1371/journal.pntd.0004065. eCollection 2015.


GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of Streptomyces lividans.

Chaplin AK, Petrus ML, Mangiameli G, Hough MA, Svistunenko DA, Nicholls P, Claessen D, Vijgenboom E, Worrall JA.

Biochem J. 2015 Aug 1;469(3):433-44. doi: 10.1042/BJ20150190. Epub 2015 Jun 11.


Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.

Hu YC, Nicholls PK, Soh YQ, Daniele JR, Junker JP, van Oudenaarden A, Page DC.

PLoS Genet. 2015 Mar 4;11(3):e1005019. doi: 10.1371/journal.pgen.1005019. eCollection 2015 Mar.


The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice.

Koenig PA, Nicholls PK, Schmidt FI, Hagiwara M, Maruyama T, Frydman GH, Watson N, Page DC, Ploegh HL.

J Biol Chem. 2014 Dec 12;289(50):34490-502. doi: 10.1074/jbc.M114.604132. Epub 2014 Oct 15.


Re-evaluation of the near infrared spectra of mitochondrial cytochrome c oxidase: Implications for non invasive in vivo monitoring of tissues.

Mason MG, Nicholls P, Cooper CE.

Biochim Biophys Acta. 2014 Nov;1837(11):1882-1891. doi: 10.1016/j.bbabio.2014.08.005. Epub 2014 Aug 29.


Reliability of clinical nerve function assessment in peripheral neuropathies.

Brandsma JW, Wagenaar I, Post E, Nicholls P, Richardus JH.

Lepr Rev. 2014 Mar;85(1):29-35.


Redox equilibration after one-electron reduction of cytochrome c oxidase: radical formation and a possible hydrogen relay mechanism.

Ashe D, Alleyne T, Wilson M, Svistunenko D, Nicholls P.

Arch Biochem Biophys. 2014 Jul 15;554:36-43. doi: 10.1016/ Epub 2014 May 5.


Susceptibility tensor imaging of the kidney and its microstructural underpinnings.

Xie L, Dibb R, Cofer GP, Li W, Nicholls PJ, Johnson GA, Liu C.

Magn Reson Med. 2015 Mar;73(3):1270-81. doi: 10.1002/mrm.25219. Epub 2014 Apr 2.

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