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Items: 1 to 20 of 23

1.

Chronic In Vivo Effects of Repeated Exposure to Low Oral Doses of Tetrodotoxin: Preliminary Evidence of Nephrotoxicity and Cardiotoxicity.

Boente-Juncal A, Vale C, Cifuentes M, Otero P, Camiña M, Rodriguez-Vieytes M, Botana LM.

Toxins (Basel). 2019 Feb 6;11(2). pii: E96. doi: 10.3390/toxins11020096.

2.

Application of pressurized liquid extraction (PLE) to obtain bioactive fatty acids and phenols from Laminaria ochroleuca collected in Galicia (NW Spain).

Otero P, López-Martínez MI, García-Risco MR.

J Pharm Biomed Anal. 2019 Feb 5;164:86-92. doi: 10.1016/j.jpba.2018.09.057. Epub 2018 Oct 15.

PMID:
30359842
3.
4.

Identification of optimum fatty acid extraction methods for two different microalgae Phaeodactylum tricornutum and Haematococcus pluvialis for food and biodiesel applications.

Otero P, Saha SK, Gushin JM, Moane S, Barron J, Murray P.

Anal Bioanal Chem. 2017 Jul;409(19):4659-4667. doi: 10.1007/s00216-017-0412-9. Epub 2017 Jun 7.

PMID:
28593370
5.

Improved method for rapid detection of phthalates in bottled water by gas chromatography-mass spectrometry.

Otero P, Saha SK, Moane S, Barron J, Clancy G, Murray P.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 1;997:229-35. doi: 10.1016/j.jchromb.2015.05.036. Epub 2015 Jun 11.

PMID:
26134297
6.

Detection of anatoxin-a and three analogs in Anabaena spp. cultures: new fluorescence polarization assay and toxin profile by LC-MS/MS.

Sanchez JA, Otero P, Alfonso A, Ramos V, Vasconcelos V, Aráoz R, Molgó J, Vieytes MR, Botana LM.

Toxins (Basel). 2014 Jan 24;6(2):402-15. doi: 10.3390/toxins6020402.

7.

Oral toxicity of okadaic acid in mice: study of lethality, organ damage, distribution and effects on detoxifying gene expression.

Vieira AC, Rubiolo JA, López-Alonso H, Cifuentes JM, Alfonso A, Bermúdez R, Otero P, Vieytes MR, Vega FV, Botana LM.

Toxins (Basel). 2013 Nov 8;5(11):2093-108. doi: 10.3390/toxins5112093.

8.

New invertebrate vectors for PST, spirolides and okadaic acid in the North Atlantic.

Silva M, Barreiro A, Rodriguez P, Otero P, Azevedo J, Alfonso A, Botana LM, Vasconcelos V.

Mar Drugs. 2013 Jun 5;11(6):1936-60. doi: 10.3390/md11061936.

9.

Benefit of 13-desmethyl spirolide C treatment in triple transgenic mouse model of Alzheimer disease: beta-amyloid and neuronal markers improvement.

Alonso E, Otero P, Vale C, Alfonso A, Antelo A, Giménez-Llort L, Chabaud L, Guillou C, Botana LM.

Curr Alzheimer Res. 2013 Mar;10(3):279-89.

PMID:
23036025
10.

Pharmacokinetic and toxicological data of spirolides after oral and intraperitoneal administration.

Otero P, Alfonso A, Rodríguez P, Rubiolo JA, Cifuentes JM, Bermúdez R, Vieytes MR, Botana LM.

Food Chem Toxicol. 2012 Feb;50(2):232-7. doi: 10.1016/j.fct.2011.10.062. Epub 2011 Nov 11.

PMID:
22100396
11.

First direct fluorescence polarization assay for the detection and quantification of spirolides in mussel samples.

Otero P, Alfonso A, Alfonso C, Aráoz R, Molgó J, Vieytes MR, Botana LM.

Anal Chim Acta. 2011 Sep 9;701(2):200-8. doi: 10.1016/j.aca.2011.05.034. Epub 2011 May 31.

PMID:
21801889
12.

13-Desmethyl spirolide-c and 13,19-didesmethyl spirolide-c trans-epithelial permeabilities: human intestinal permeability modelling.

Espiña B, Otero P, Louzao MC, Alfonso A, Botana LM.

Toxicology. 2011 Sep 5;287(1-3):69-75. doi: 10.1016/j.tox.2011.06.003. Epub 2011 Jun 12.

PMID:
21689715
13.

Effect of uncontrolled factors in a validated liquid chromatography-tandem mass spectrometry method question its use as a reference method for marine toxins: major causes for concern.

Otero P, Alfonso A, Alfonso C, Rodríguez P, Vieytes MR, Botana LM.

Anal Chem. 2011 Aug 1;83(15):5903-11. doi: 10.1021/ac200732m. Epub 2011 Jun 29.

PMID:
21651235
14.

A comparative study of the effect of ciguatoxins on voltage-dependent Na+ and K+ channels in cerebellar neurons.

Pérez S, Vale C, Alonso E, Alfonso C, Rodríguez P, Otero P, Alfonso A, Vale P, Hirama M, Vieytes MR, Botana LM.

Chem Res Toxicol. 2011 Apr 18;24(4):587-96. doi: 10.1021/tx200043j. Epub 2011 Mar 21.

PMID:
21351754
15.

Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii.

Otero P, Alfonso A, Vieytes MR, Cabado AG, Vieites JM, Botana LM.

Environ Toxicol Chem. 2010 Feb;29(2):301-10. doi: 10.1002/etc.41.

PMID:
20821448
16.

First toxin profile of ciguateric fish in Madeira Arquipelago (Europe).

Otero P, Pérez S, Alfonso A, Vale C, Rodríguez P, Gouveia NN, Gouveia N, Delgado J, Vale P, Hirama M, Ishihara Y, Molgó J, Botana LM.

Anal Chem. 2010 Jul 15;82(14):6032-9. doi: 10.1021/ac100516q.

PMID:
20557036
17.

Detection of 13,19-didesmethyl C spirolide by fluorescence polarization using Torpedo electrocyte membranes.

Fonfría ES, Vilariño N, Molgó J, Aráoz R, Otero P, Espiña B, Louzao MC, Alvarez M, Botana LM.

Anal Biochem. 2010 Aug;403(1-2):102-7. doi: 10.1016/j.ab.2010.04.006. Epub 2010 Apr 9.

PMID:
20382103
18.

New protocol to obtain spirolides from Alexandrium ostenfeldii cultures with high recovery and purity.

Otero P, Alfonso A, Alfonso C, Vieytes MR, Louzao MC, Botana AM, Botana LM.

Biomed Chromatogr. 2010 Aug;24(8):878-86. doi: 10.1002/bmc.1380.

PMID:
20087843
19.

Selective, potent PPARgamma agonists with cyclopentenone core structure.

Otero MP, Pérez Santín E, Rodríguez-Barrios F, Vaz B, de Lera AR.

Bioorg Med Chem Lett. 2009 Apr 1;19(7):1883-6. doi: 10.1016/j.bmcl.2009.02.072. Epub 2009 Feb 23.

PMID:
19275963
20.

Evaluation of various pH and temperature conditions on the stability of azaspiracids and their importance in preparative isolation and toxicological studies.

Alfonso C, Rehmann N, Hess P, Alfonso A, Wandscheer CB, Abuín M, Vale C, Otero P, Vieytes MR, Botana LM.

Anal Chem. 2008 Dec 15;80(24):9672-80. doi: 10.1021/ac801506d.

PMID:
19072271

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