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Items: 1 to 20 of 67


Prevention of clinical and histological signs of MOG-induced experimental allergic encephalomyelitis by prolonged treatment with recombinant human EGF.

Nicoletti F, Mazzon E, Fagone P, Mangano K, Mammana S, Cavalli E, Basile MS, Bramanti P, Scalabrino G, Lange A, Curtin F.

J Neuroimmunol. 2019 May 8;332:224-232. doi: 10.1016/j.jneuroim.2019.05.006. [Epub ahead of print]


Overexpression of Nudt7 decreases bile acid levels and peroxisomal fatty acid oxidation in the liver.

Shumar SA, Kerr EW, Fagone P, Infante AM, Leonardi R.

J Lipid Res. 2019 May;60(5):1005-1019. doi: 10.1194/jlr.M092676. Epub 2019 Mar 7.


KCNMA1 Expression is Downregulated in Colorectal Cancer via Epigenetic Mechanisms.

Basile MS, Fagone P, Mangano K, Mammana S, Magro G, Salvatorelli L, Li Destri G, La Greca G, Nicoletti F, Puleo S, Pesce A.

Cancers (Basel). 2019 Feb 19;11(2). pii: E245. doi: 10.3390/cancers11020245.


Differential modulation and prognostic values of immune-escape genes in uveal melanoma.

Basile MS, Mazzon E, Russo A, Mammana S, Longo A, Bonfiglio V, Fallico M, Caltabiano R, Fagone P, Nicoletti F, Avitabile T, Reibaldi M.

PLoS One. 2019 Jan 17;14(1):e0210276. doi: 10.1371/journal.pone.0210276. eCollection 2019.


Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets.

Günther S, Fagone P, Jalce G, Atanasov AG, Guignabert C, Nicoletti F.

Drug Discov Today. 2019 Feb;24(2):428-439. doi: 10.1016/j.drudis.2018.11.003. Epub 2018 Nov 13. Review.


Overexpression of macrophage migration inhibitory factor and functionally-related genes, D-DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma.

Presti M, Mazzon E, Basile MS, Petralia MC, Bramanti A, Colletti G, Bramanti P, Nicoletti F, Fagone P.

Oncol Lett. 2018 Sep;16(3):2881-2886. doi: 10.3892/ol.2018.8990. Epub 2018 Jun 19.


Gasotransmitters and the immune system: Mode of action and novel therapeutic targets.

Fagone P, Mazzon E, Bramanti P, Bendtzen K, Nicoletti F.

Eur J Pharmacol. 2018 Sep 5;834:92-102. doi: 10.1016/j.ejphar.2018.07.026. Epub 2018 Jul 20. Review.


Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis.

Fagone P, Mazzon E, Chikovani T, Saraceno A, Mammana S, Colletti G, Mangano K, Bramanti P, Nicoletti F.

J Neuroimmunol. 2018 Aug 15;321:41-48. doi: 10.1016/j.jneuroim.2018.05.013. Epub 2018 May 28.


Biological Self-Assembly and Recognition Used to Synthesize and Surface Guide Next Generation of Hybrid Materials.

Hu X, Fagone P, Dong C, Su R, Xu Q, Dinu CZ.

ACS Appl Mater Interfaces. 2018 Aug 29;10(34):28372-28381. doi: 10.1021/acsami.8b09421. Epub 2018 Aug 20.


Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences.

Fagone P, Mazzon E, Cavalli E, Bramanti A, Petralia MC, Mangano K, Al-Abed Y, Bramati P, Nicoletti F.

J Neuroimmunol. 2018 Sep 15;322:46-56. doi: 10.1016/j.jneuroim.2018.06.009. Epub 2018 Jun 15.


Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach.

Mangano K, Mazzon E, Basile MS, Di Marco R, Bramanti P, Mammana S, Petralia MC, Fagone P, Nicoletti F.

Oncotarget. 2018 Apr 3;9(25):17951-17970. doi: 10.18632/oncotarget.24885. eCollection 2018 Apr 3. Review.


Naturally occurring compounds in differentiation based therapy of cancer.

Mijatović S, Bramanti A, Nicoletti F, Fagone P, Kaluđerović GN, Maksimović-Ivanić D.

Biotechnol Adv. 2018 Nov 1;36(6):1622-1632. doi: 10.1016/j.biotechadv.2018.04.001. Epub 2018 Apr 12. Review.


The Role of Macrophages in Neuroinflammatory and Neurodegenerative Pathways of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis: Pathogenetic Cellular Effectors and Potential Therapeutic Targets.

Mammana S, Fagone P, Cavalli E, Basile MS, Petralia MC, Nicoletti F, Bramanti P, Mazzon E.

Int J Mol Sci. 2018 Mar 13;19(3). pii: E831. doi: 10.3390/ijms19030831. Review.


Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis.

Mammana S, Bramanti P, Mazzon E, Cavalli E, Basile MS, Fagone P, Petralia MC, McCubrey JA, Nicoletti F, Mangano K.

Oncotarget. 2018 Jan 3;9(9):8263-8277. doi: 10.18632/oncotarget.23862. eCollection 2018 Feb 2.


Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform.

Shumar SA, Kerr EW, Geldenhuys WJ, Montgomery GE, Fagone P, Thirawatananond P, Saavedra H, Gabelli SB, Leonardi R.

J Biol Chem. 2018 Mar 16;293(11):4134-4148. doi: 10.1074/jbc.RA117.001358. Epub 2018 Jan 29.


Involvement of the Nrf2/HO-1/CO axis and therapeutic intervention with the CO-releasing molecule CORM-A1, in a murine model of autoimmune hepatitis.

Mangano K, Cavalli E, Mammana S, Basile MS, Caltabiano R, Pesce A, Puleo S, Atanasov AG, Magro G, Nicoletti F, Fagone P.

J Cell Physiol. 2018 May;233(5):4156-4165. doi: 10.1002/jcp.26223. Epub 2017 Dec 29.


Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

Donia M, Harbst K, van Buuren M, Kvistborg P, Lindberg MF, Andersen R, Idorn M, Munir Ahmad S, Ellebæk E, Mueller A, Fagone P, Nicoletti F, Libra M, Lauss M, Hadrup SR, Schmidt H, Andersen MH, Thor Straten P, Nilsson JA, Schumacher TN, Seliger B, Jönsson G, Svane IM.

Cancer Res. 2017 Sep 1;77(17):4562-4566. doi: 10.1158/0008-5472.CAN-16-3172. Epub 2017 Jun 27.


Identification of novel chemotherapeutic strategies for metastatic uveal melanoma.

Fagone P, Caltabiano R, Russo A, Lupo G, Anfuso CD, Basile MS, Longo A, Nicoletti F, De Pasquale R, Libra M, Reibaldi M.

Sci Rep. 2017 Mar 17;7:44564. doi: 10.1038/srep44564.


HIV-protease inhibitors for the treatment of cancer: Repositioning HIV protease inhibitors while developing more potent NO-hybridized derivatives?

Maksimovic-Ivanic D, Fagone P, McCubrey J, Bendtzen K, Mijatovic S, Nicoletti F.

Int J Cancer. 2017 Apr 15;140(8):1713-1726. doi: 10.1002/ijc.30529. Epub 2017 Jan 20. Review.


Standardized bovine colostrum derivative impedes development of type 1 diabetes in rodents.

Nikolic I, Stojanovic I, Vujicic M, Fagone P, Mangano K, Stosic-Grujicic S, Nicoletti F, Saksida T.

Immunobiology. 2017 Feb;222(2):272-279. doi: 10.1016/j.imbio.2016.09.013. Epub 2016 Sep 24.


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