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Items: 15

1.

Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities.

Wu Y, Parapini S, Williams ID, Misiano P, Wong HN, Taramelli D, Basilico N, Haynes RK.

Molecules. 2018 Jul 13;23(7). pii: E1713. doi: 10.3390/molecules23071713.

2.

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.

Basilico N, Parapini S, Sparatore A, Romeo S, Misiano P, Vivas L, Yardley V, Croft SL, Habluetzel A, Lucantoni L, Renia L, Russell B, Suwanarusk R, Nosten F, Dondio G, Bigogno C, Jabes D, Taramelli D.

Molecules. 2017 Dec 1;22(12). pii: E2102. doi: 10.3390/molecules22122102.

3.

Malaria pigment stimulates chemokine production by human microvascular endothelium.

Basilico N, Corbett Y, D' Alessandro S, Parapini S, Prato M, Girelli D, Misiano P, Olliaro P, Taramelli D.

Acta Trop. 2017 Aug;172:125-131. doi: 10.1016/j.actatropica.2017.05.002. Epub 2017 May 2.

PMID:
28476599
4.

Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity.

D'Alessandro S, Corbett Y, Ilboudo DP, Misiano P, Dahiya N, Abay SM, Habluetzel A, Grande R, Gismondo MR, Dechering KJ, Koolen KM, Sauerwein RW, Taramelli D, Basilico N, Parapini S.

Antimicrob Agents Chemother. 2015 Sep;59(9):5135-44. doi: 10.1128/AAC.04332-14. Epub 2015 Jun 8.

5.

Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.

Fariello RG, Ghelardini C, Di Cesare Mannelli L, Bonanno G, Pittaluga A, Milanese M, Misiano P, Farina C.

Neuropharmacology. 2014 Jun;81:85-94. doi: 10.1016/j.neuropharm.2014.01.029. Epub 2014 Jan 31.

PMID:
24486381
6.

Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death.

van Schalkwyk DA, Chan XW, Misiano P, Gagliardi S, Farina C, Saliba KJ.

Biochem Pharmacol. 2010 May 1;79(9):1291-9. doi: 10.1016/j.bcp.2009.12.025. Epub 2010 Jan 11.

PMID:
20067768
7.

Biological effects of a new vacuolar-H,-ATPase inhibitor in colon carcinoma cell lines.

Supino R, Scovassi AI, Croce AC, Dal Bo L, Favini E, Corbelli A, Farina C, Misiano P, Zunino F.

Ann N Y Acad Sci. 2009 Aug;1171:606-16. doi: 10.1111/j.1749-6632.2009.04705.x.

PMID:
19723111
8.

Antimetastatic effect of a small-molecule vacuolar H+-ATPase inhibitor in in vitro and in vivo preclinical studies.

Supino R, Petrangolini G, Pratesi G, Tortoreto M, Favini E, Bo LD, Casalini P, Radaelli E, Croce AC, Bottiroli G, Misiano P, Farina C, Zunino F.

J Pharmacol Exp Ther. 2008 Jan;324(1):15-22. Epub 2007 Oct 1.

PMID:
17909082
9.

Evaluation of in vitro brain penetration: optimized PAMPA and MDCKII-MDR1 assay comparison.

Carrara S, Reali V, Misiano P, Dondio G, Bigogno C.

Int J Pharm. 2007 Dec 10;345(1-2):125-33. Epub 2007 May 31.

PMID:
17624703
10.

Discovery of diaryl imidazolidin-2-one derivatives, a novel class of muscarinic M3 selective antagonists (Part 1).

Peretto I, Forlani R, Fossati C, Giardina GA, Giardini A, Guala M, La Porta E, Petrillo P, Radaelli S, Radice L, Raveglia LF, Santoro E, Scudellaro R, Scarpitta F, Bigogno C, Misiano P, Dondio GM, Rizzi A, Armani E, Amari G, Civelli M, Villetti G, Patacchini R, Bergamaschi M, Delcanale M, Salcedo C, Fernández AG, Imbimbo BP.

J Med Chem. 2007 Apr 5;50(7):1571-83. Epub 2007 Mar 13.

PMID:
17352462
11.

New perspectives in bio-analytical techniques for preclinical characterization of a drug candidate: UPLC-MS/MS in in vitro metabolism and pharmacokinetic studies.

Pedraglio S, Rozio MG, Misiano P, Reali V, Dondio G, Bigogno C.

J Pharm Biomed Anal. 2007 Jul 27;44(3):665-73. Epub 2006 Dec 17.

PMID:
17236736
12.

Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins.

Petrangolini G, Supino R, Pratesi G, Dal Bo L, Tortoreto M, Croce AC, Misiano P, Belfiore P, Farina C, Zunino F.

J Pharmacol Exp Ther. 2006 Sep;318(3):939-46. Epub 2006 May 19.

PMID:
16714402
13.

Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.

Peretto I, Radaelli S, Parini C, Zandi M, Raveglia LF, Dondio G, Fontanella L, Misiano P, Bigogno C, Rizzi A, Riccardi B, Biscaioli M, Marchetti S, Puccini P, Catinella S, Rondelli I, Cenacchi V, Bolzoni PT, Caruso P, Villetti G, Facchinetti F, Del Giudice E, Moretto N, Imbimbo BP.

J Med Chem. 2005 Sep 8;48(18):5705-20.

PMID:
16134939
14.

Antagonism between the anti-inflammatory activity of the cannabinoid WIN 55212-2 and SR 141716A.

Pozzi O, Misiano P, Clark GD, Visentin L.

Pharmacology. 2003 Nov;69(3):158-63.

PMID:
14512703
15.

PTH2 receptor-mediated inhibitory effect of parathyroid hormone and TIP39 on cell proliferation.

Misiano P, Scott BB, Scheideler MA, Garnier M.

Eur J Pharmacol. 2003 May 16;468(3):159-66.

PMID:
12754053

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