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Items: 1 to 20 of 28


Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy.

Hsu HY, Hwang PA.

Clin Transl Med. 2019 May 1;8(1):15. doi: 10.1186/s40169-019-0234-9. Review.


The anti-tumor activity of brown seaweed oligo-fucoidan via lncRNA expression modulation in HepG2 cells.

Yan MD, Lin HY, Hwang PA.

Cytotechnology. 2019 Feb;71(1):363-374. doi: 10.1007/s10616-019-00293-7. Epub 2019 Jan 10.


Fabrication and Characterization of Strontium-Substituted Hydroxyapatite-CaO-CaCO₃ Nanofibers with a Mesoporous Structure as Drug Delivery Carriers.

Tsai SW, Yu WX, Hwang PA, Huang SS, Lin HM, Hsu YW, Hsu FY.

Pharmaceutics. 2018 Oct 8;10(4). pii: E179. doi: 10.3390/pharmaceutics10040179.


Bacteriostatic Effect of a Calcined Waste Clamshell-Activated Plastic Film for Food Packaging.

Kao CY, Huang YC, Chiu SY, Kuo KL, Hwang PA.

Materials (Basel). 2018 Aug 7;11(8). pii: E1370. doi: 10.3390/ma11081370.


Alleviative effect of fucoxanthin-containing extract from brown seaweed Laminaria japonica on renal tubular cell apoptosis through upregulating Na+/H+ exchanger NHE1 in chronic kidney disease mice.

Chen YC, Cheng CY, Liu CT, Sue YM, Chen TH, Hsu YH, Hwang PA, Chen CH.

J Ethnopharmacol. 2018 Oct 5;224:391-399. doi: 10.1016/j.jep.2018.06.023. Epub 2018 Jun 18.


Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression.

Chen LM, Liu PY, Chen YA, Tseng HY, Shen PC, Hwang PA, Hsu HL.

Sci Rep. 2017 Sep 19;7(1):11864. doi: 10.1038/s41598-017-12111-1.


Fabrication and Cytotoxicity of Fucoidan-Cisplatin Nanoparticles for Macrophage and Tumor Cells.

Hwang PA, Lin XZ, Kuo KL, Hsu FY.

Materials (Basel). 2017 Mar 14;10(3). pii: E291. doi: 10.3390/ma10030291.


Fucoidan ameliorates pancreatic β-cell death and impaired insulin synthesis in streptozotocin-treated β cells and mice via a Sirt-1-dependent manner.

Yu WC, Chen YL, Hwang PA, Chen TH, Chou TC.

Mol Nutr Food Res. 2017 Oct;61(10). doi: 10.1002/mnfr.201700136. Epub 2017 Jun 8.


Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway.

Chen CH, Sue YM, Cheng CY, Chen YC, Liu CT, Hsu YH, Hwang PA, Huang NJ, Chen TH.

Sci Rep. 2017 Jan 18;7:40183. doi: 10.1038/srep40183.


Low-molecular-weight fucoidan and high-stability fucoxanthin from brown seaweed exert prebiotics and anti-inflammatory activities in Caco-2 cells.

Hwang PA, Phan NN, Lu WJ, Ngoc Hieu BT, Lin YC.

Food Nutr Res. 2016 Aug 2;60:32033. doi: 10.3402/fnr.v60.32033. eCollection 2016.


Toxicological Evaluation of Low Molecular Weight Fucoidan in Vitro and in Vivo.

Hwang PA, Yan MD, Lin HT, Li KL, Lin YC.

Mar Drugs. 2016 Jun 24;14(7). pii: E121. doi: 10.3390/md14070121.


Fucoidan Elevates MicroRNA-29b to Regulate DNMT3B-MTSS1 Axis and Inhibit EMT in Human Hepatocellular Carcinoma Cells.

Yan MD, Yao CJ, Chow JM, Chang CL, Hwang PA, Chuang SE, Whang-Peng J, Lai GM.

Mar Drugs. 2015 Sep 24;13(10):6099-116. doi: 10.3390/md13106099.


The in vitro and in vivo effects of the low molecular weight fucoidan on the bone osteogenic differentiation properties.

Hwang PA, Hung YL, Phan NN, Hieu BT, Chang PM, Li KL, Lin YC.

Cytotechnology. 2016 Aug;68(4):1349-59. doi: 10.1007/s10616-015-9894-5. Epub 2015 Aug 14.


Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia.

Chen MC, Hsu WL, Hwang PA, Chou TC.

Mar Drugs. 2015 Jul 17;13(7):4436-51. doi: 10.3390/md13074436.


Inhibitory effects of high stability fucoxanthin on palmitic acid-induced lipid accumulation in human adipose-derived stem cells through modulation of long non-coding RNA.

Lin WC, Shih PH, Wang W, Wu CH, Hsia SM, Wang HJ, Hwang PA, Wang CY, Chen SH, Kuo YT.

Food Funct. 2015 Jul;6(7):2215-23. doi: 10.1039/c5fo00301f.


Inhibitory activity of Sargassum hemiphyllum sulfated polysaccharide in arachidonic acid-induced animal models of inflammation.

Hwang PA, Hung YL, Chien SY.

J Food Drug Anal. 2015 Mar;23(1):49-56. doi: 10.1016/j.jfda.2014.05.004. Epub 2014 Oct 29.


Taurine resumed neuronal differentiation in arsenite-treated N2a cells through reducing oxidative stress, endoplasmic reticulum stress, and mitochondrial dysfunction.

Chou CT, Lin HT, Hwang PA, Wang ST, Hsieh CH, Hwang DF.

Amino Acids. 2015 Apr;47(4):735-44. doi: 10.1007/s00726-014-1901-1. Epub 2014 Dec 30.


The brown seaweed Sargassum hemiphyllum exhibits α-amylase and α-glucosidase inhibitory activity and enhances insulin release in vitro.

Hwang PA, Hung YL, Tsai YK, Chien SY, Kong ZL.

Cytotechnology. 2015 Aug;67(4):653-60. doi: 10.1007/s10616-014-9745-9. Epub 2014 Oct 26.

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