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Items: 1 to 20 of 76

1.

Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages.

Xavier C, Blykers A, Laoui D, Bolli E, Vaneyken I, Bridoux J, Baudhuin H, Raes G, Everaert H, Movahedi K, Van Ginderachter JA, Devoogdt N, Caveliers V, Lahoutte T, Keyaerts M.

Mol Imaging Biol. 2019 Jan 22. doi: 10.1007/s11307-018-01302-5. [Epub ahead of print]

PMID:
30671739
2.

Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios.

Zhou Z, McDougald D, Devoogdt N, Zalutsky MR, Vaidyanathan G.

Mol Pharm. 2019 Jan 7;16(1):214-226. doi: 10.1021/acs.molpharmaceut.8b00951. Epub 2018 Nov 28.

PMID:
30427188
3.

An Efficient Method for Labeling Single Domain Antibody Fragments with 18F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker.

Zhou Z, Devoogdt N, Zalutsky MR, Vaidyanathan G.

Bioconjug Chem. 2018 Dec 19;29(12):4090-4103. doi: 10.1021/acs.bioconjchem.8b00699. Epub 2018 Nov 14.

PMID:
30384599
4.

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis.

Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C.

JACC Cardiovasc Imaging. 2018 Oct 12. pii: S1936-878X(18)30753-8. doi: 10.1016/j.jcmg.2018.07.027. [Epub ahead of print]

5.

Direct fluorine-18 labeling of heat-sensitive biomolecules for positron emission tomography imaging using the Al18F-RESCA method.

Cleeren F, Lecina J, Bridoux J, Devoogdt N, Tshibangu T, Xavier C, Bormans G.

Nat Protoc. 2018 Oct;13(10):2330-2347. doi: 10.1038/s41596-018-0040-7.

PMID:
30250289
6.

Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis - impact of radiochemistry on pharmacokinetics.

Bala G, Crauwels M, Blykers A, Remory I, Marschall ALJ, Dübel S, Dumas L, Broisat A, Martin C, Ballet S, Cosyns B, Caveliers V, Devoogdt N, Xavier C, Hernot S.

Biol Chem. 2019 Feb 25;400(3):323-332. doi: 10.1515/hsz-2018-0330.

PMID:
30240352
7.

Site-Specific Radioactive Labeling of Nanobodies.

Crauwels M, Massa S, Martin C, Betti C, Ballet S, Devoogdt N, Xavier C, Muyldermans S.

Methods Mol Biol. 2018;1827:505-540. doi: 10.1007/978-1-4939-8648-4_26.

PMID:
30196514
8.

Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy.

Broos K, Lecocq Q, Raes G, Devoogdt N, Keyaerts M, Breckpot K.

Theranostics. 2018 Jun 7;8(13):3559-3570. doi: 10.7150/thno.24762. eCollection 2018. Review.

9.

Pharmacokinetics of radiolabeled dimeric sdAbs constructs targeting human CD20.

Krasniqi A, Bialkowska M, Xavier C, Van der Jeught K, Muyldermans S, Devoogdt N, D'Huyvetter M.

N Biotechnol. 2018 Oct 25;45:69-79. doi: 10.1016/j.nbt.2018.03.004. Epub 2018 Mar 21.

PMID:
29574274
10.

Same-Day Imaging Using Small Proteins: Clinical Experience and Translational Prospects in Oncology.

Krasniqi A, D'Huyvetter M, Devoogdt N, Frejd FY, Sörensen J, Orlova A, Keyaerts M, Tolmachev V.

J Nucl Med. 2018 Jun;59(6):885-891. doi: 10.2967/jnumed.117.199901. Epub 2018 Mar 15. Review.

PMID:
29545374
11.

Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation.

Zhou Z, Chitneni SK, Devoogdt N, Zalutsky MR, Vaidyanathan G.

Bioorg Med Chem. 2018 May 1;26(8):1939-1949. doi: 10.1016/j.bmc.2018.02.040. Epub 2018 Mar 15.

12.

A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.

Balhuizen A, Massa S, Mathijs I, Turatsinze JV, De Vos J, Demine S, Xavier C, Villate O, Millard I, Egrise D, Capito C, Scharfmann R, In't Veld P, Marchetti P, Muyldermans S, Goldman S, Lahoutte T, Bouwens L, Eizirik DL, Devoogdt N.

Sci Rep. 2017 Nov 9;7(1):15130. doi: 10.1038/s41598-017-15417-2.

13.

Improved Debulking of Peritoneal Tumor Implants by Near-Infrared Fluorescent Nanobody Image Guidance in an Experimental Mouse Model.

Debie P, Vanhoeij M, Poortmans N, Puttemans J, Gillis K, Devoogdt N, Lahoutte T, Hernot S.

Mol Imaging Biol. 2018 Jun;20(3):361-367. doi: 10.1007/s11307-017-1134-2.

PMID:
29090412
14.

Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma.

Krasniqi A, D'Huyvetter M, Xavier C, Van der Jeught K, Muyldermans S, Van Der Heyden J, Lahoutte T, Tavernier J, Devoogdt N.

Mol Cancer Ther. 2017 Dec;16(12):2828-2839. doi: 10.1158/1535-7163.MCT-17-0554. Epub 2017 Oct 20.

15.

Evaluation of [99mTc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice.

Bala G, Baudhuin H, Remory I, Gillis K, Debie P, Krasniqi A, Lahoutte T, Raes G, Devoogdt N, Cosyns B, Hernot S.

Mol Imaging Biol. 2018 Apr;20(2):260-267. doi: 10.1007/s11307-017-1117-3.

PMID:
28875290
16.

Al18F-Labeling Of Heat-Sensitive Biomolecules for Positron Emission Tomography Imaging.

Cleeren F, Lecina J, Ahamed M, Raes G, Devoogdt N, Caveliers V, McQuade P, Rubins DJ, Li W, Verbruggen A, Xavier C, Bormans G.

Theranostics. 2017 Jul 14;7(11):2924-2939. doi: 10.7150/thno.20094. eCollection 2017.

17.

131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment.

D'Huyvetter M, De Vos J, Xavier C, Pruszynski M, Sterckx YGJ, Massa S, Raes G, Caveliers V, Zalutsky MR, Lahoutte T, Devoogdt N.

Clin Cancer Res. 2017 Nov 1;23(21):6616-6628. doi: 10.1158/1078-0432.CCR-17-0310. Epub 2017 Jul 27.

18.

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model.

Verhelle A, Nair N, Everaert I, Van Overbeke W, Supply L, Zwaenepoel O, Peleman C, Van Dorpe J, Lahoutte T, Devoogdt N, Derave W, Chuah MK, VandenDriessche T, Gettemans J.

Hum Mol Genet. 2017 Aug 1;26(15):3030. doi: 10.1093/hmg/ddx207. No abstract available.

PMID:
28605435
19.

Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased β2 Adrenergic Receptor Ligands.

Martin C, Moors SLC, Danielsen M, Betti C, Fabris C, Sejer Pedersen D, Pardon E, Peyressatre M, Fehér K, Martins JC, Mosolff Mathiesen J, Morris MC, Devoogdt N, Caveliers V, De Proft F, Steyaert J, Ballet S.

Chemistry. 2017 Jul 18;23(40):9632-9640. doi: 10.1002/chem.201701321. Epub 2017 Jun 29.

PMID:
28449310
20.

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers.

Broos K, Keyaerts M, Lecocq Q, Renmans D, Nguyen T, Escors D, Liston A, Raes G, Breckpot K, Devoogdt N.

Oncotarget. 2017 Jun 27;8(26):41932-41946. doi: 10.18632/oncotarget.16708.

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