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Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission-confounded by the gut microbiome?

Leong RWL, Kaakoush NO, Yau YY, Wasinger VC.

Aliment Pharmacol Ther. 2019 Apr;49(8):1086-1087. doi: 10.1111/apt.15171. No abstract available.


Impacts of Diet and Exercise on Maternal Gut Microbiota Are Transferred to Offspring.

Bhagavata Srinivasan SP, Raipuria M, Bahari H, Kaakoush NO, Morris MJ.

Front Endocrinol (Lausanne). 2018 Nov 29;9:716. doi: 10.3389/fendo.2018.00716. eCollection 2018.


Signatures within the esophageal microbiome are associated with host genetics, age, and disease.

Deshpande NP, Riordan SM, Castaño-Rodríguez N, Wilkins MR, Kaakoush NO.

Microbiome. 2018 Dec 17;6(1):227. doi: 10.1186/s40168-018-0611-4.


OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus.

Castaño-Rodríguez N, Popple GL, Porras-Hurtado GL, Cardona-Deazza JL, Montoya-Martinez JJ, Cadavid-Velez AJ, Toro-Hidalgo HW, Cobo-Alvarado AR, Del Socorro Hincapié-Rincón O, Riordan SM, Kaakoush NO.

Biomark Res. 2018 Dec 7;6:35. doi: 10.1186/s40364-018-0150-y. eCollection 2018.


A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome.

Mathur A, Feng S, Hayward JA, Ngo C, Fox D, Atmosukarto II, Price JD, Schauer K, Märtlbauer E, Robertson AAB, Burgio G, Fox EM, Leppla SH, Kaakoush NO, Man SM.

Nat Microbiol. 2019 Feb;4(2):362-374. doi: 10.1038/s41564-018-0318-0. Epub 2018 Dec 10.


Specific Bacteria and Metabolites Associated With Response to Fecal Microbiota Transplantation in Patients With Ulcerative Colitis.

Paramsothy S, Nielsen S, Kamm MA, Deshpande NP, Faith JJ, Clemente JC, Paramsothy R, Walsh AJ, van den Bogaerde J, Samuel D, Leong RWL, Connor S, Ng W, Lin E, Borody TJ, Wilkins MR, Colombel JF, Mitchell HM, Kaakoush NO.

Gastroenterology. 2019 Apr;156(5):1440-1454.e2. doi: 10.1053/j.gastro.2018.12.001. Epub 2018 Dec 6.


High plasma FGF21 levels predicts major cardiovascular events in patients treated with atorvastatin (from the Treating to New Targets [TNT] Study).

Ong KL, Hui N, Januszewski AS, Kaakoush NO, Xu A, Fayyad R, DeMicco DA, Jenkins AJ, Keech AC, Waters DD, Barter PJ, Rye KA.

Metabolism. 2019 Apr;93:93-99. doi: 10.1016/j.metabol.2018.11.006. Epub 2018 Nov 16.


Gastrointestinal Pathobionts in Pediatric Crohn's Disease Patients.

Purcell RV, Kaakoush NO, Mitchell HM, Pearson JF, Keenan JI.

Int J Microbiol. 2018 Jul 17;2018:9203908. doi: 10.1155/2018/9203908. eCollection 2018.


Ultraviolet Irradiation of Skin Alters the Faecal Microbiome Independently of Vitamin D in Mice.

Ghaly S, Kaakoush NO, Lloyd F, Gordon L, Forest C, Lawrance IC, Hart PH.

Nutrients. 2018 Aug 11;10(8). pii: E1069. doi: 10.3390/nu10081069.


High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis.

Ghaly S, Kaakoush NO, Lloyd F, McGonigle T, Mok D, Baird A, Klopcic B, Gordon L, Gorman S, Forest C, Bouillon R, Lawrance IC, Hart PH.

Sci Rep. 2018 Jul 31;8(1):11511. doi: 10.1038/s41598-018-29759-y.


Gut Microbiome Analysis Identifies Potential Etiological Factors in Acute Gastroenteritis.

Castaño-Rodríguez N, Underwood AP, Merif J, Riordan SM, Rawlinson WD, Mitchell HM, Kaakoush NO.

Infect Immun. 2018 Jun 21;86(7). pii: e00060-18. doi: 10.1128/IAI.00060-18. Print 2018 Jul.


NAFLD, Helicobacter species and the intestinal microbiome.

Castaño-Rodríguez N, Mitchell HM, Kaakoush NO.

Best Pract Res Clin Gastroenterol. 2017 Dec;31(6):657-668. doi: 10.1016/j.bpg.2017.09.008. Epub 2017 Sep 5. Review.


Microbiome and Esophageal Adenocarcinoma-Letter.

Kaakoush NO.

Cancer Res. 2018 Mar 15;78(6):1574. doi: 10.1158/0008-5472.CAN-17-3791. Epub 2018 Feb 28. No abstract available.


Dysbiosis of the microbiome in gastric carcinogenesis.

Castaño-Rodríguez N, Goh KL, Fock KM, Mitchell HM, Kaakoush NO.

Sci Rep. 2017 Nov 21;7(1):15957. doi: 10.1038/s41598-017-16289-2.


Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

Paramsothy S, Paramsothy R, Rubin DT, Kamm MA, Kaakoush NO, Mitchell HM, Castaño-Rodríguez N.

J Crohns Colitis. 2017 Oct 1;11(10):1180-1199. doi: 10.1093/ecco-jcc/jjx063. Review.


Cross-talk among metabolic parameters, esophageal microbiota, and host gene expression following chronic exposure to an obesogenic diet.

Kaakoush NO, Lecomte V, Maloney CA, Morris MJ.

Sci Rep. 2017 Mar 31;7:45753. doi: 10.1038/srep45753.


More Flavor for Flavonoid-Based Interventions?

Kaakoush NO, Morris MJ.

Trends Mol Med. 2017 Apr;23(4):293-295. doi: 10.1016/j.molmed.2017.02.008. Epub 2017 Mar 17.


Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial.

Paramsothy S, Kamm MA, Kaakoush NO, Walsh AJ, van den Bogaerde J, Samuel D, Leong RWL, Connor S, Ng W, Paramsothy R, Xuan W, Lin E, Mitchell HM, Borody TJ.

Lancet. 2017 Mar 25;389(10075):1218-1228. doi: 10.1016/S0140-6736(17)30182-4. Epub 2017 Feb 15.


Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells.

Deshpande NP, Wilkins MR, Castaño-Rodríguez N, Bainbridge E, Sodhi N, Riordan SM, Mitchell HM, Kaakoush NO.

Sci Rep. 2016 Sep 28;6:34288. doi: 10.1038/srep34288.


Is there a role for stool metabolomics in cystic fibrosis?

Kaakoush NO, Pickford R, Jaffe A, Ooi CY.

Pediatr Int. 2016 Aug;58(8):808-11. doi: 10.1111/ped.13063. Review.


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