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Items: 1 to 20 of 34


Using Machine Learning to Predict Progression in the Gastric Precancerous Process in a Population from a Developing Country Who Underwent a Gastroscopy for Dyspeptic Symptoms.

Thapa S, Fischbach LA, Delongchamp R, Faramawi MF, Orloff MS.

Gastroenterol Res Pract. 2019 Apr 1;2019:8321942. doi: 10.1155/2019/8321942. eCollection 2019.


The Association between Salt and Potential Mediators of the Gastric Precancerous Process.

Thapa S, Fischbach LA, Delongchamp R, Faramawi MF, Orloff M.

Cancers (Basel). 2019 Apr 15;11(4). pii: E535. doi: 10.3390/cancers11040535.


Association between Dietary Salt Intake and Progression in the Gastric Precancerous Process.

Thapa S, Fischbach LA, Delongchamp R, Faramawi MF, Orloff M.

Cancers (Basel). 2019 Apr 3;11(4). pii: E467. doi: 10.3390/cancers11040467.


Genome-wide tracts of homozygosity and exome analyses reveal repetitive elements with Barrets esophagus/esophageal adenocarcinoma risk.

Wanchai V, Jin J, Bircan E, Eng C, Orloff M.

BMC Bioinformatics. 2019 Mar 14;20(Suppl 2):98. doi: 10.1186/s12859-019-2622-y.


PARP1 Is Up-Regulated in Non-small Cell Lung Cancer Tissues in the Presence of the Cyanobacterial Toxin Microcystin.

Apopa PL, Alley L, Penney RB, Arnaoutakis K, Steliga MA, Jeffus S, Bircan E, Gopalan B, Jin J, Patumcharoenpol P, Jenjaroenpun P, Wongsurawat T, Shah N, Boysen G, Ussery D, Nookaew I, Fagan P, Bebek G, Orloff MS.

Front Microbiol. 2018 Aug 6;9:1757. doi: 10.3389/fmicb.2018.01757. eCollection 2018.


Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients.

Makhoul I, Todorova VK, Siegel ER, Erickson SW, Dhakal I, Raj VR, Lee JY, Orloff MS, Griffin RJ, Henry-Tillman RS, Klimberg S, Hutchins LF, Kadlubar SA.

PLoS One. 2017 Jan 3;12(1):e0168550. doi: 10.1371/journal.pone.0168550. eCollection 2017.


2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer.

Rogers LJ, Basnakian AG, Orloff MS, Ning B, Yao-Borengasser A, Raj V, Kadlubar S.

Nutr Metab (Lond). 2016 Aug 20;13:54. doi: 10.1186/s12986-016-0111-0. eCollection 2016.


Tuberculosis and leprosy infections in the Marshallese population of Arkansas, USA.

Cardenas VM, Orloff MS, Kaminaga J, Cardenas IC, Brown J, Hainline-Williams S, Duthie MS, Gonzalez-Puche AC, Mukasa L, Patil N, Mcelfish PA, Bates JH.

Lepr Rev. 2016 Mar;87(1):109-12.


Association of specific PTEN/10q haplotypes with endometrial cancer phenotypes in African-American and European American women.

Sutton J, Orloff MS, Michener C, Chiesa-Vottero A, Prayson R, Nowacki AS, Eng C.

Gynecol Oncol. 2015 Aug;138(2):434-40. doi: 10.1016/j.ygyno.2015.05.024. Epub 2015 May 28.


Genotypic and allelic variability in CYP19A1 among populations of African and European ancestry.

Starlard-Davenport A, Orloff MS, Dhakal I, Penney RB, Kadlubar SA.

PLoS One. 2015 Feb 3;10(2):e0117347. doi: 10.1371/journal.pone.0117347. eCollection 2015.


cgaTOH: extended approach for identifying tracts of homozygosity.

Zhang L, Orloff MS, Reber S, Li S, Zhao Y, Eng C.

PLoS One. 2013;8(3):e57772. doi: 10.1371/journal.pone.0057772. Epub 2013 Mar 1.


Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.

Ngeow J, Heald B, Rybicki LA, Orloff MS, Chen JL, Liu X, Yerian L, Willis J, Lehtonen HJ, Lehtonen R, Mester JL, Moline J, Burke CA, Church J, Aaltonen LA, Eng C.

Gastroenterology. 2013 Jun;144(7):1402-9, 1409.e1-5. doi: 10.1053/j.gastro.2013.02.001. Epub 2013 Feb 8.


Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes.

Orloff MS, He X, Peterson C, Chen F, Chen JL, Mester JL, Eng C.

Am J Hum Genet. 2013 Jan 10;92(1):76-80. doi: 10.1016/j.ajhg.2012.10.021. Epub 2012 Dec 13.


Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes.

Ngeow J, He X, Mester JL, Lei J, Romigh T, Orloff MS, Milas M, Eng C.

J Clin Endocrinol Metab. 2012 Dec;97(12):E2320-7. doi: 10.1210/jc.2012-2944. Epub 2012 Oct 12.


Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort.

Orloff MS, Zhang L, Bebek G, Eng C.

PLoS One. 2012;7(2):e31975. doi: 10.1371/journal.pone.0031975. Epub 2012 Feb 27.


Integrated analysis reveals critical genomic regions in prostate tumor microenvironment associated with clinicopathologic phenotypes.

Ashida S, Orloff MS, Bebek G, Zhang L, Zheng P, Peehl DM, Eng C.

Clin Cancer Res. 2012 Mar 15;18(6):1578-87. doi: 10.1158/1078-0432.CCR-11-2535. Epub 2012 Jan 24.


Lifetime cancer risks in individuals with germline PTEN mutations.

Tan MH, Mester JL, Ngeow J, Rybicki LA, Orloff MS, Eng C.

Clin Cancer Res. 2012 Jan 15;18(2):400-7. doi: 10.1158/1078-0432.CCR-11-2283.


Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.

Ni Y, He X, Chen J, Moline J, Mester J, Orloff MS, Ringel MD, Eng C.

Hum Mol Genet. 2012 Jan 15;21(2):300-10. doi: 10.1093/hmg/ddr459. Epub 2011 Oct 6.


Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma.

Bebek G, Orloff M, Eng C.

J Clin Bioinforma. 2011 Aug 2;1(1):21. doi: 10.1186/2043-9113-1-21.


Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma.

Orloff M, Peterson C, He X, Ganapathi S, Heald B, Yang YR, Bebek G, Romigh T, Song JH, Wu W, David S, Cheng Y, Meltzer SJ, Eng C.

JAMA. 2011 Jul 27;306(4):410-9. doi: 10.1001/jama.2011.1029.

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