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Items: 1 to 20 of 76

1.

Expression of drug metabolizing enzymes and transporters in the cochlea: Implications for drug delivery and ototoxicity.

Kennon-McGill S, Clemens MM, McGill MR.

Hear Res. 2019 May 15;379:98-102. doi: 10.1016/j.heares.2019.05.002. [Epub ahead of print]

PMID:
31121337
2.

Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model.

Ewing LE, Skinner CM, Quick CM, Kennon-McGill S, McGill MR, Walker LA, ElSohly MA, Gurley BJ, Koturbash I.

Molecules. 2019 Apr 30;24(9). pii: E1694. doi: 10.3390/molecules24091694.

3.

Animal models of drug-induced liver injury.

McGill MR, Jaeschke H.

Biochim Biophys Acta Mol Basis Dis. 2019 May 1;1865(5):1031-1039. doi: 10.1016/j.bbadis.2018.08.037. Epub 2018 Sep 3. Review.

PMID:
31007174
4.

Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F₁ Mice.

Gurley BJ, Miousse IR, Nookaew I, Ewing LE, Skinner CM, Jenjaroenpun P, Wongsurawat T, Kennon-McGill S, Avula B, Bae JY, McGill MR, Ussery D, Khan IA, Koturbash I.

Nutrients. 2019 Apr 3;11(4). pii: E776. doi: 10.3390/nu11040776.

5.

Propagation of Pericentral Necrosis During Acetaminophen-Induced Liver Injury: Evidence for Early Interhepatocyte Communication and Information Exchange.

Kennedy RC, Smith AK, Ropella GEP, McGill MR, Jaeschke H, Hunt CA.

Toxicol Sci. 2019 May 1;169(1):151-166. doi: 10.1093/toxsci/kfz029.

6.

The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling.

Clemens MM, Kennon-McGill S, Apte U, James LP, Finck BN, McGill MR.

Food Chem Toxicol. 2019 Mar;125:279-288. doi: 10.1016/j.fct.2019.01.014. Epub 2019 Jan 14.

PMID:
30654094
7.

Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways.

Kennedy JL, Kurten RC, McCullough S, Panettieri RA, Koziol-White C, Jones SM, Caid K, Gill PS, Roberts D, Jaeschke H, McGill MR, James L.

Xenobiotica. 2019 Jan 30:1-10. doi: 10.1080/00498254.2018.1536814. [Epub ahead of print]

PMID:
30328361
8.

The Problem With Predictive Values: Are We Using the Right Metrics for Preclinical Prediction of Drug Hepatotoxicity?

McGill MR.

Toxicol Sci. 2018 Sep 1;165(1):3-4. doi: 10.1093/toxsci/kfy157. No abstract available.

PMID:
30165627
9.

Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation.

McGill MR, Jaeschke H.

Expert Rev Mol Diagn. 2018 Sep;18(9):797-807. doi: 10.1080/14737159.2018.1508998. Epub 2018 Aug 13. Review.

PMID:
30080986
10.

Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.

Lutkewitte AJ, Schweitzer GG, Kennon-McGill S, Clemens MM, James LP, Jaeschke H, Finck BN, McGill MR.

Food Chem Toxicol. 2018 May;115:273-283. doi: 10.1016/j.fct.2018.03.014. Epub 2018 Mar 11. No abstract available.

11.

EXTRAHEPATIC TOXICITY OF ACETAMINOPHEN: CRITICAL EVALUATION OF THE EVIDENCE AND PROPOSED MECHANISMS.

Kennon-McGill S, McGill MR.

J Clin Transl Res. 2018 Jan 15;3(3). pii: 5. doi: 10.18053/jctres.03.201703.005. Epub 2017 Nov 18.

12.

Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis.

McGreal SR, Bhushan B, Walesky C, McGill MR, Lebofsky M, Kandel SE, Winefield RD, Jaeschke H, Zachara NE, Zhang Z, Tan EP, Slawson C, Apte U.

Toxicol Sci. 2018 Apr 1;162(2):599-610. doi: 10.1093/toxsci/kfy002.

13.

Increased C-Reactive Protein in Healthy Controls.

McGill MR, Gronowski AM.

Clin Chem. 2018 Jan;64(1):242-243. doi: 10.1373/clinchem.2017.274746. No abstract available.

14.

Extrahepatic toxicity of acetaminophen: critical evaluation of the evidence and proposed mechanisms.

Kennon-McGill S, McGill MR.

J Clin Transl Res. 2017 Nov 18;3(3):297-310. eCollection 2018 Jan 15. Review.

15.

Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.

Du K, Ramachandran A, McGill MR, Mansouri A, Asselah T, Farhood A, Woolbright BL, Ding WX, Jaeschke H.

Food Chem Toxicol. 2017 Oct;108(Pt A):339-350. doi: 10.1016/j.fct.2017.08.020. Epub 2017 Aug 18.

16.

Professionalism in Residency Training: A Compilation of Desirable Behaviors and a Case-Based Comparison Between Pathologists in Training and Practice.

Gronowski AM, McGill MR, Domen RE.

Acad Pathol. 2016 Sep 16;3:2374289516667509. doi: 10.1177/2374289516667509. eCollection 2016 Jan-Dec.

17.

Erratum to: Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity.

Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Weemhoff JL, Tiburcio T, Pereira IVA, Willebrords J, Yanguas SC, Farhood A, Beschin A, Van Ginderachter JA, Penuela S, Jaeschke H, Cogliati B, Vinken M.

Arch Toxicol. 2017 May;91(5):2263-2264. doi: 10.1007/s00204-016-1929-y. No abstract available.

PMID:
28243680
18.

Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.

Bhushan B, Chavan H, Borude P, Xie Y, Du K, McGill MR, Lebofsky M, Jaeschke H, Krishnamurthy P, Apte U.

Toxicol Sci. 2017 Feb;155(2):363-378. doi: 10.1093/toxsci/kfw213. Epub 2016 Oct 23.

19.

Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity.

Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Weemhoff JL, Tiburcio T, Veloso Alves Pereira I, Willebrords J, Crespo Yanguas S, Farhood A, Beschin A, Van Ginderachter JA, Penuela S, Jaeschke H, Cogliati B, Vinken M.

Arch Toxicol. 2017 May;91(5):2245-2261. doi: 10.1007/s00204-016-1885-6. Epub 2016 Nov 8. Erratum in: Arch Toxicol. 2017 May;91(5):2263-2264.

20.

Falsely Elevated Plasma Creatinine Due to an Immunoglobulin M Paraprotein.

McGill MR, Vijayan A, Trulock EP, Witt CA, Kohler GD, Scott MG.

Am J Kidney Dis. 2016 Nov;68(5):789-792. doi: 10.1053/j.ajkd.2016.05.014. Epub 2016 Jul 22.

PMID:
27461852

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