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Items: 7

1.

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy.

Levene M, Bain MD, Moran NF, Nirmalananthan N, Poulton J, Scarpelli M, Filosto M, Mandel H, MacKinnon AD, Fairbanks L, Pacitti D, Bax BE.

J Clin Med. 2019 Apr 5;8(4). pii: E457. doi: 10.3390/jcm8040457.

2.

Mitochondrial Neurogastrointestinal Encephalomyopathy: Into the Fourth Decade, What We Have Learned So Far.

Pacitti D, Levene M, Garone C, Nirmalananthan N, Bax BE.

Front Genet. 2018 Dec 21;9:669. doi: 10.3389/fgene.2018.00669. eCollection 2018. Review.

3.

Discovery profiling and bioinformatics analysis of serum microRNA in Mitochondrial NeuroGastroIntestinal Encephalomyopathy (MNGIE).

Levene M, Enguita FJ, Bax BE.

Nucleosides Nucleotides Nucleic Acids. 2018;37(11):618-629. doi: 10.1080/15257770.2018.1492138. Epub 2018 Dec 27.

PMID:
30587073
4.

Validation of an Immunoassay for Anti-thymidine Phosphorylase Antibodies in Patients with MNGIE Treated with Enzyme Replacement Therapy.

Levene M, Pacitti D, Gasson C, Hall J, Sellos-Moura M, Bax BE.

Mol Ther Methods Clin Dev. 2018 Aug 28;11:1-8. doi: 10.1016/j.omtm.2018.08.007. eCollection 2018 Dec 14.

5.

Validation of a HPLC method for the measurement of erythrocyte encapsulated thymidine phosphorylase (EE-TP) activity.

Fairbanks LD, Levene M, Bax BE.

J Pharm Biomed Anal. 2013 Mar 25;76:8-12. doi: 10.1016/j.jpba.2012.12.006. Epub 2012 Dec 17.

PMID:
23291437
6.

The development and validation of an immunoassay for the measurement of anti-thymidine phosphorylase antibodies in mouse and dog sera.

Gasson C, Levene M, Bax BE.

J Pharm Biomed Anal. 2013 Jan;72:16-24. doi: 10.1016/j.jpba.2012.09.009. Epub 2012 Sep 23.

PMID:
23146222
7.

Preclinical toxicity evaluation of erythrocyte-encapsulated thymidine phosphorylase in BALB/c mice and beagle dogs: an enzyme-replacement therapy for mitochondrial neurogastrointestinal encephalomyopathy.

Levene M, Coleman DG, Kilpatrick HC, Fairbanks LD, Gangadharan B, Gasson C, Bax BE.

Toxicol Sci. 2013 Jan;131(1):311-24. doi: 10.1093/toxsci/kfs278. Epub 2012 Sep 12.

PMID:
22977166

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