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Items: 16


Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA polymerase β.

Howard MJ, Foley KG, Shock DD, Batra VK, Wilson SH.

J Biol Chem. 2019 May 3;294(18):7194-7201. doi: 10.1074/jbc.RA118.006809. Epub 2019 Mar 18.


DNA scanning by base excision repair enzymes and implications for pathway coordination.

Howard MJ, Wilson SH.

DNA Repair (Amst). 2018 Nov;71:101-107. doi: 10.1016/j.dnarep.2018.08.013. Epub 2018 Aug 25. Review.


Unencumbered Pol β lyase activity in nucleosome core particles.

Rodriguez Y, Howard MJ, Cuneo MJ, Prasad R, Wilson SH.

Nucleic Acids Res. 2017 Sep 6;45(15):8901-8915. doi: 10.1093/nar/gkx593.


Processive searching ability varies among members of the gap-filling DNA polymerase X family.

Howard MJ, Wilson SH.

J Biol Chem. 2017 Oct 20;292(42):17473-17481. doi: 10.1074/jbc.M117.801860. Epub 2017 Sep 11.


DNA polymerase β uses its lyase domain in a processive search for DNA damage.

Howard MJ, Rodriguez Y, Wilson SH.

Nucleic Acids Res. 2017 Apr 20;45(7):3822-3832. doi: 10.1093/nar/gkx047.


The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions.

Klemm BP, Wu N, Chen Y, Liu X, Kaitany KJ, Howard MJ, Fierke CA.

Biomolecules. 2016 May 13;6(2). pii: E27. doi: 10.3390/biom6020027. Review.


Differential substrate recognition by isozymes of plant protein-only Ribonuclease P.

Howard MJ, Karasik A, Klemm BP, Mei C, Shanmuganathan A, Fierke CA, Koutmos M.

RNA. 2016 May;22(5):782-92. doi: 10.1261/rna.055541.115. Epub 2016 Mar 10.


Nuclear Protein-Only Ribonuclease P2 Structure and Biochemical Characterization Provide Insight into the Conserved Properties of tRNA 5' End Processing Enzymes.

Karasik A, Shanmuganathan A, Howard MJ, Fierke CA, Koutmos M.

J Mol Biol. 2016 Jan 16;428(1):26-40. doi: 10.1016/j.jmb.2015.11.025. Epub 2015 Dec 3.


Mechanistic Studies Reveal Similar Catalytic Strategies for Phosphodiester Bond Hydrolysis by Protein-only and RNA-dependent Ribonuclease P.

Howard MJ, Klemm BP, Fierke CA.

J Biol Chem. 2015 May 22;290(21):13454-64. doi: 10.1074/jbc.M115.644831. Epub 2015 Mar 27.


RNase P enzymes: divergent scaffolds for a conserved biological reaction.

Howard MJ, Liu X, Lim WH, Klemm BP, Fierke CA, Koutmos M, Engelke DR.

RNA Biol. 2013 Jun;10(6):909-14. doi: 10.4161/rna.24513. Epub 2013 Apr 1.


Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing.

Howard MJ, Lim WH, Fierke CA, Koutmos M.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16149-54. doi: 10.1073/pnas.1209062109. Epub 2012 Sep 18.


The Escherichia coli alkylation response protein AidB is a redox partner of flavodoxin and binds RNA and acyl carrier protein.

Mulrooney SB, Howard MJ, Hausinger RP.

Arch Biochem Biophys. 2011 Sep 15;513(2):81-6. doi: 10.1016/ Epub 2011 Jul 18.


Unit-level voluntary turnover rates and customer service quality: implications of group cohesiveness, newcomer concentration, and size.

Hausknecht JP, Trevor CO, Howard MJ.

J Appl Psychol. 2009 Jul;94(4):1068-75. doi: 10.1037/a0015898.


An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.

Bernal-Mizrachi C, Xiaozhong L, Yin L, Knutsen RH, Howard MJ, Arends JJ, Desantis P, Coleman T, Semenkovich CF.

Cell Metab. 2007 Feb;5(2):91-102.


Transplantation of apoptosis-resistant embryonic stem cells into the injured rat spinal cord.

Howard MJ, Liu S, Schottler F, Joy Snider B, Jacquin MF.

Somatosens Mot Res. 2005 Mar-Jun;22(1-2):37-44.


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