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Items: 1 to 20 of 67

1.

Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy.

Pallocca M, Angeli D, Palombo F, Sperati F, Milella M, Goeman F, De Nicola F, Fanciulli M, Nisticò P, Quintarelli C, Ciliberto G.

J Transl Med. 2019 Apr 23;17(1):131. doi: 10.1186/s12967-019-1865-8.

2.

PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?

Bazzichetto C, Conciatori F, Pallocca M, Falcone I, Fanciulli M, Cognetti F, Milella M, Ciuffreda L.

Cancers (Basel). 2019 Mar 28;11(4). pii: E435. doi: 10.3390/cancers11040435. Review.

3.

Reverse Engineering Cancer: Inferring Transcriptional Gene Signatures from Copy Number Aberrations with ICAro.

Angeli D, Fanciulli M, Pallocca M.

Cancers (Basel). 2019 Feb 22;11(2). pii: E256. doi: 10.3390/cancers11020256.

4.

Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth.

Aurisicchio L, Salvatori E, Lione L, Bandini S, Pallocca M, Maggio R, Fanciulli M, De Nicola F, Goeman F, Ciliberto G, Conforti A, Luberto L, Palombo F.

J Exp Clin Cancer Res. 2019 Feb 14;38(1):78. doi: 10.1186/s13046-019-1084-4.

5.

Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis.

Caforio M, Sorino C, Iacovelli S, Fanciulli M, Locatelli F, Folgiero V.

J Exp Clin Cancer Res. 2018 Sep 27;37(1):239. doi: 10.1186/s13046-018-0912-2. Review.

6.

The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression.

Buglioni S, Melucci E, Sperati F, Pallocca M, Terrenato I, De Nicola F, Goeman F, Casini B, Amoreo CA, Gallo E, Diodoro MG, Pescarmona E, Vici P, Sergi D, Pizzuti L, Di Lauro L, Mazzotta M, Barba M, Fanciulli M, Vitale I, De Maria R, Ciliberto G, Maugeri-Saccà M.

Oncoimmunology. 2018 Apr 24;7(8):e1457602. doi: 10.1080/2162402X.2018.1457602. eCollection 2018.

7.

Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer.

Pallocca M, Goeman F, De Nicola F, Melucci E, Sperati F, Terrenato I, Pizzuti L, Casini B, Gallo E, Amoreo CA, Vici P, Di Lauro L, Buglioni S, Diodoro MG, Pescarmona E, Mazzotta M, Barba M, Fanciulli M, De Maria R, Ciliberto G, Maugeri-Saccà M.

J Transl Med. 2018 Sep 4;16(1):247. doi: 10.1186/s12967-018-1607-3.

8.

Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer.

De Nicola F, Goeman F, Pallocca M, Sperati F, Pizzuti L, Melucci E, Casini B, Amoreo CA, Gallo E, Diodoro MG, Buglioni S, Mazzotta M, Vici P, Sergi D, Di Lauro L, Barba M, Pescarmona E, Ciliberto G, De Maria R, Fanciulli M, Maugeri-Saccà M.

Oncogenesis. 2018 Jul 22;7(7):55. doi: 10.1038/s41389-018-0066-2.

9.

A new baby in the c-Myc-directed transcriptional machinery: Che-1/AATF.

Folgiero V, Sorino C, Locatelli F, Fanciulli M.

Cell Cycle. 2018;17(11):1286-1290. doi: 10.1080/15384101.2018.1480227. Epub 2018 Jul 25.

PMID:
29943642
10.

Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy.

Melucci E, Casini B, Ronchetti L, Pizzuti L, Sperati F, Pallocca M, De Nicola F, Goeman F, Gallo E, Amoreo CA, Sergi D, Terrenato I, Vici P, Di Lauro L, Diodoro MG, Pescarmona E, Barba M, Mazzotta M, Mottolese M, Fanciulli M, Ciliberto G, De Maria R, Buglioni S, Maugeri-Saccà M.

J Transl Med. 2018 Feb 5;16(1):22. doi: 10.1186/s12967-018-1385-y.

11.

Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.

Folgiero V, Sorino C, Pallocca M, De Nicola F, Goeman F, Bertaina V, Strocchio L, Romania P, Pitisci A, Iezzi S, Catena V, Bruno T, Strimpakos G, Passananti C, Mattei E, Blandino G, Locatelli F, Fanciulli M.

EMBO Rep. 2018 Mar;19(3). pii: e44871. doi: 10.15252/embr.201744871. Epub 2018 Jan 24.

12.

Conditionally reprogrammed cells (CRC) methodology does not allow the in vitro expansion of patient-derived primary and metastatic lung cancer cells.

Sette G, Salvati V, Giordani I, Pilozzi E, Quacquarini D, Duranti E, De Nicola F, Pallocca M, Fanciulli M, Falchi M, Pallini R, De Maria R, Eramo A.

Int J Cancer. 2018 Jul 1;143(1):88-99. doi: 10.1002/ijc.31260. Epub 2018 Jan 26.

PMID:
29341112
13.

AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer.

Welcker D, Jain M, Khurshid S, Jokić M, Höhne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Büttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Höpker K.

Oncogene. 2018 Mar;37(11):1503-1518. doi: 10.1038/s41388-017-0054-6. Epub 2018 Jan 11.

PMID:
29321668
14.

Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities.

Pulito C, Mori F, Sacconi A, Goeman F, Ferraiuolo M, Pasanisi P, Campagnoli C, Berrino F, Fanciulli M, Ford RJ, Levrero M, Pediconi N, Ciuffreda L, Milella M, Steinberg GR, Cioce M, Muti P, Strano S, Blandino G.

Cell Discov. 2017 Jul 4;3:17022. doi: 10.1038/celldisc.2017.22. eCollection 2017.

15.

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.

Manic G, Signore M, Sistigu A, Russo G, Corradi F, Siteni S, Musella M, Vitale S, De Angelis ML, Pallocca M, Amoreo CA, Sperati F, Di Franco S, Barresi S, Policicchio E, De Luca G, De Nicola F, Mottolese M, Zeuner A, Fanciulli M, Stassi G, Maugeri-Saccà M, Baiocchi M, Tartaglia M, Vitale I, De Maria R.

Gut. 2018 May;67(5):903-917. doi: 10.1136/gutjnl-2016-312623. Epub 2017 Apr 7.

16.

DNA damage repair and survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy.

Ronchetti L, Melucci E, De Nicola F, Goeman F, Casini B, Sperati F, Pallocca M, Terrenato I, Pizzuti L, Vici P, Sergi D, Di Lauro L, Amoreo CA, Gallo E, Diodoro MG, Pescarmona E, Vitale I, Barba M, Buglioni S, Mottolese M, Fanciulli M, De Maria R, Maugeri-Saccà M.

Int J Cancer. 2017 Jun 1;140(11):2587-2595. doi: 10.1002/ijc.30668. Epub 2017 Mar 11.

17.

Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.

Bruno T, Valerio M, Casadei L, De Nicola F, Goeman F, Pallocca M, Catena V, Iezzi S, Sorino C, Desantis A, Manetti C, Blandino G, Floridi A, Fanciulli M.

J Exp Clin Cancer Res. 2017 Feb 18;36(1):32. doi: 10.1186/s13046-017-0497-1.

18.

Deptor: not only a mTOR inhibitor.

Catena V, Fanciulli M.

J Exp Clin Cancer Res. 2017 Jan 13;36(1):12. doi: 10.1186/s13046-016-0484-y. Review.

19.

Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells.

Catena V, Bruno T, De Nicola F, Goeman F, Pallocca M, Iezzi S, Sorino C, Cigliana G, Floridi A, Blandino G, Fanciulli M.

Oncotarget. 2016 Oct 25;7(43):70546-70558. doi: 10.18632/oncotarget.12060.

20.

eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts.

Pisani C, Onori A, Gabanella F, Delle Monache F, Borreca A, Ammassari-Teule M, Fanciulli M, Di Certo MG, Passananti C, Corbi N.

J Exp Clin Cancer Res. 2016 Sep 17;35(1):146. doi: 10.1186/s13046-016-0424-x.

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