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Items: 1 to 20 of 36

1.

Hemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species.

Turrini E, Catanzaro E, Ferruzzi L, Guerrini A, Tacchini M, Sacchetti G, Paganetto G, Maffei F, Pellicioni V, Poli F, Hrelia P, Mandrone M, Sestili P, Brigotti M, Fimognari C.

Sci Rep. 2019 May 10;9(1):7199. doi: 10.1038/s41598-019-43609-5.

2.

The structure of the Shiga toxin 2a A-subunit dictates the interactions of the toxin with blood components.

Brigotti M, Orth-Höller D, Carnicelli D, Porcellini E, Galassi E, Tazzari PL, Ricci F, Manoli F, Manet I, Talasz H, Lindner HH, Speth C, Erbeznik T, Fuchs S, Posch W, Chatterjee S, Würzner R.

Cell Microbiol. 2019 May;21(5):e13000. doi: 10.1111/cmi.13000. Epub 2019 Jan 18.

3.

Soluble Toll-Like Receptor 4 Impairs the Interaction of Shiga Toxin 2a with Human Serum Amyloid P Component.

Brigotti M, Arfilli V, Carnicelli D, Ricci F, Tazzari PL, Ardissino G, Scavia G, Morabito S, He X.

Toxins (Basel). 2018 Sep 18;10(9). pii: E379. doi: 10.3390/toxins10090379.

4.

Human monocytes stimulated by Shiga toxin 1a via globotriaosylceramide release proinflammatory molecules associated with hemolytic uremic syndrome.

Brigotti M, Carnicelli D, Arfilli V, Porcellini E, Galassi E, Valerii MC, Spisni E.

Int J Med Microbiol. 2018 Oct;308(7):940-946. doi: 10.1016/j.ijmm.2018.06.013. Epub 2018 Jul 2.

PMID:
29983334
5.

An Improved Method for the Sensitive Detection of Shiga Toxin 2 in Human Serum.

He X, Ardissino G, Patfield S, Cheng LW, Silva CJ, Brigotti M.

Toxins (Basel). 2018 Jan 31;10(2). pii: E59. doi: 10.3390/toxins10020059.

6.

The inhibition of lactate dehydrogenase A hinders the transcription of histone 2B gene independently from the block of aerobic glycolysis.

Brighenti E, Carnicelli D, Brigotti M, Fiume L.

Biochem Biophys Res Commun. 2017 Apr 15;485(4):742-745. doi: 10.1016/j.bbrc.2017.02.119. Epub 2017 Feb 28.

PMID:
28257841
7.

Cap-independent protein synthesis is enhanced by betaine under hypertonic conditions.

Carnicelli D, Arfilli V, Onofrillo C, Alfieri RR, Petronini PG, Montanaro L, Brigotti M.

Biochem Biophys Res Commun. 2017 Feb 12;483(3):936-940. doi: 10.1016/j.bbrc.2017.01.035. Epub 2017 Jan 10.

PMID:
28082201
8.

A reconstituted cell-free assay for the evaluation of the intrinsic activity of purified human ribosomes.

Penzo M, Carnicelli D, Montanaro L, Brigotti M.

Nat Protoc. 2016 Jul;11(7):1309-25. doi: 10.1038/nprot.2016.072. Epub 2016 Jun 23.

PMID:
27336708
9.

The Antibiotic Polymyxin B Impairs the Interactions between Shiga Toxins and Human Neutrophils.

Carnicelli D, Arfilli V, Ricci F, Velati C, Tazzari PL, Brigotti M.

J Immunol. 2016 Feb 1;196(3):1177-85. doi: 10.4049/jimmunol.1500671. Epub 2015 Dec 22.

10.

Early Volume Expansion and Outcomes of Hemolytic Uremic Syndrome.

Ardissino G, Tel F, Possenti I, Testa S, Consonni D, Paglialonga F, Salardi S, Borsa-Ghiringhelli N, Salice P, Tedeschi S, Castorina P, Colombo RM, Arghittu M, Daprai L, Monzani A, Tozzoli R, Brigotti M, Torresani E.

Pediatrics. 2016 Jan;137(1). doi: 10.1542/peds.2015-2153. Epub 2015 Dec 7.

11.

A rapid and sensitive method to measure the functional activity of Shiga toxins in human serum.

Arfilli V, Carnicelli D, Ardissino G, Torresani E, Scavia G, Brigotti M.

Toxins (Basel). 2015 Nov 4;7(11):4564-76. doi: 10.3390/toxins7114564.

12.

Serum Shiga toxin 2 values in patients during acute phase of diarrhoea-associated haemolytic uraemic syndrome.

He X, Quiñones B, Loo MT, Loos S, Scavia G, Brigotti M, Levtchenko E, Monnens L.

Acta Paediatr. 2015 Dec;104(12):e564-8. doi: 10.1111/apa.13211. Epub 2015 Nov 2.

PMID:
26361237
13.

RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes.

Lauria F, Tebaldi T, Lunelli L, Struffi P, Gatto P, Pugliese A, Brigotti M, Montanaro L, Ciribilli Y, Inga A, Quattrone A, Sanguinetti G, Viero G.

Nucleic Acids Res. 2015 Dec 15;43(22):e153. doi: 10.1093/nar/gkv781. Epub 2015 Aug 3.

14.

Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation.

Penzo M, Rocchi L, Brugiere S, Carnicelli D, Onofrillo C, Couté Y, Brigotti M, Montanaro L.

FASEB J. 2015 Aug;29(8):3472-82. doi: 10.1096/fj.15-270991. Epub 2015 May 1.

15.

Identification of TLR4 as the receptor that recognizes Shiga toxins in human neutrophils.

Brigotti M, Carnicelli D, Arfilli V, Tamassia N, Borsetti F, Fabbri E, Tazzari PL, Ricci F, Pagliaro P, Spisni E, Cassatella MA.

J Immunol. 2013 Nov 1;191(9):4748-58. doi: 10.4049/jimmunol.1300122. Epub 2013 Sep 25.

16.

Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation.

Rocchi L, Pacilli A, Sethi R, Penzo M, Schneider RJ, Treré D, Brigotti M, Montanaro L.

Nucleic Acids Res. 2013 Sep;41(17):8308-18. doi: 10.1093/nar/gkt587. Epub 2013 Jul 1.

17.

Shiga toxin 1, as DNA repair inhibitor, synergistically potentiates the activity of the anticancer drug, mafosfamide, on raji cells.

Brigotti M, Arfilli V, Carnicelli D, Rocchi L, Calcabrini C, Ricci F, Pagliaro P, Tazzari PL, Alfieri RR, Petronini PG, Sestili P.

Toxins (Basel). 2013 Feb 21;5(2):431-44. doi: 10.3390/toxins5020431.

18.

5'-Untranslated region of heat shock protein 70 mRNA drives translation under hypertonic conditions.

Rocchi L, Alfieri RR, Petronini PG, Montanaro L, Brigotti M.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):321-5. doi: 10.1016/j.bbrc.2012.12.100. Epub 2013 Jan 3.

PMID:
23291172
19.

Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells.

Fiume L, Vettraino M, Carnicelli D, Arfilli V, Di Stefano G, Brigotti M.

Biochem Biophys Res Commun. 2013 Jan 11;430(2):466-9. doi: 10.1016/j.bbrc.2012.12.013. Epub 2012 Dec 10.

PMID:
23237800
20.

The interactions of human neutrophils with shiga toxins and related plant toxins: danger or safety?

Brigotti M.

Toxins (Basel). 2012 Mar;4(3):157-90. doi: 10.3390/toxins4030157. Epub 2012 Mar 1. Review.

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