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Items: 1 to 20 of 175

1.

Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage.

Hatsuta H, Takao M, Nogami A, Uchino A, Sumikura H, Takata T, Morimoto S, Kanemaru K, Adachi T, Arai T, Hasegawa M, Murayama S.

Acta Neuropathol Commun. 2019 Mar 28;7(1):49. doi: 10.1186/s40478-019-0700-z.

2.

Phosphorylated and aggregated TDP-43 with seeding properties are induced upon mutant Huntingtin (mHtt) polyglutamine expression in human cellular models.

Coudert L, Nonaka T, Bernard E, Hasegawa M, Schaeffer L, Leblanc P.

Cell Mol Life Sci. 2019 Mar 12. doi: 10.1007/s00018-019-03059-8. [Epub ahead of print]

PMID:
30863908
3.

N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APPSw,Ind Mice.

Franco R, Aguinaga D, Reyes I, Canela EI, Lillo J, Tarutani A, Hasegawa M, Del Ser-Badia A, Del Rio JA, Kreutz MR, Saura CA, Navarro G.

Front Mol Neurosci. 2018 Aug 28;11:273. doi: 10.3389/fnmol.2018.00273. eCollection 2018.

4.

The effect of truncation on prion-like properties of α-synuclein.

Terada M, Suzuki G, Nonaka T, Kametani F, Tamaoka A, Hasegawa M.

J Biol Chem. 2018 Sep 7;293(36):13910-13920. doi: 10.1074/jbc.RA118.001862. Epub 2018 Jul 20.

PMID:
30030380
5.

C9ORF72 dipeptide repeat poly-GA inclusions promote: intracellular aggregation of phosphorylated TDP-43.

Nonaka T, Masuda-Suzukake M, Hosokawa M, Shimozawa A, Hirai S, Okado H, Hasegawa M.

Hum Mol Genet. 2018 May 10. doi: 10.1093/hmg/ddy174. [Epub ahead of print]

PMID:
29750243
6.

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.

Tarutani A, Arai T, Murayama S, Hisanaga SI, Hasegawa M.

Acta Neuropathol Commun. 2018 Apr 18;6(1):29. doi: 10.1186/s40478-018-0532-2.

7.

An autopsy case of globular glial tauopathy presenting with clinical features of motor neuron disease with dementia and iron deposition in the motor cortex.

Hasegawa I, Takeda A, Hatsuta H, Kubo Y, Ohsawa M, Nakano Y, Ikeuchi T, Hasegawa M, Murayama S, Itoh Y.

Neuropathology. 2018 Mar 6. doi: 10.1111/neup.12457. [Epub ahead of print]

PMID:
29508434
8.

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease.

Kametani F, Hasegawa M.

Front Neurosci. 2018 Jan 30;12:25. doi: 10.3389/fnins.2018.00025. eCollection 2018. Review.

9.

Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome.

Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H.

Sci Rep. 2018 Jan 16;8(1):819. doi: 10.1038/s41598-018-19198-0.

10.

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.

Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, Dawson TM, Takahashi R.

Stem Cell Reports. 2018 Feb 13;10(2):356-365. doi: 10.1016/j.stemcr.2017.12.001. Epub 2018 Jan 11.

11.

Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.

Tuerde D, Kimura T, Miyasaka T, Furusawa K, Shimozawa A, Hasegawa M, Ando K, Hisanaga SI.

J Biol Chem. 2018 Feb 2;293(5):1781-1793. doi: 10.1074/jbc.M117.798918. Epub 2017 Dec 1.

12.

Frontotemporal dementia with trans-activation response DNA-binding protein 43 presenting with catatonic syndrome.

Watanabe R, Kawakami I, Onaya M, Higashi S, Arai N, Akiyama H, Hasegawa M, Arai T.

Neuropathology. 2018 Jun;38(3):281-287. doi: 10.1111/neup.12442. Epub 2017 Nov 7.

PMID:
29110334
13.

Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation.

Okada T, Keino-Masu K, Nagamine S, Kametani F, Ohto T, Hasegawa M, van Kuppevelt TH, Kunita S, Takahashi S, Masu M.

Sci Rep. 2017 Oct 23;7(1):13847. doi: 10.1038/s41598-017-14185-3.

14.

Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease.

Mano T, Nagata K, Nonaka T, Tarutani A, Imamura T, Hashimoto T, Bannai T, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamasaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido TC, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9645-E9654. doi: 10.1073/pnas.1707151114. Epub 2017 Oct 17.

15.

Molecular mechanisms of the co-deposition of multiple pathological proteins in neurodegenerative diseases.

Nonaka T, Masuda-Suzukake M, Hasegawa M.

Neuropathology. 2018 Feb;38(1):64-71. doi: 10.1111/neup.12427. Epub 2017 Sep 25. Review.

PMID:
28948653
16.

Pathological and immunoblot analysis of phosphorylated TDP-43 in sporadic amyotrophic lateral sclerosis with pallido-nigro-luysian degeneration.

Uchino A, Ogino M, Takahashi-Fujigasaki J, Oonuma S, Kanazawa N, Kajita S, Ichinoe M, Hasegawa M, Nishiyama K, Murayama S.

Neuropathology. 2018 Apr;38(2):171-178. doi: 10.1111/neup.12430. Epub 2017 Sep 14.

PMID:
28906030
17.

Progranulin haploinsufficiency reduces amyloid beta deposition in Alzheimer's disease model mice.

Hosokawa M, Tanaka Y, Arai T, Kondo H, Akiyama H, Hasegawa M.

Exp Anim. 2018 Feb 9;67(1):63-70. doi: 10.1538/expanim.17-0060. Epub 2017 Aug 25.

18.

Following the fate of endocytosed fibrils.

Hasegawa M, Suzuki G.

J Biol Chem. 2017 Aug 11;292(32):13498-13499. doi: 10.1074/jbc.H117.780296.

19.

TDP-43 stabilises the processing intermediates of mitochondrial transcripts.

Izumikawa K, Nobe Y, Yoshikawa H, Ishikawa H, Miura Y, Nakayama H, Nonaka T, Hasegawa M, Egawa N, Inoue H, Nishikawa K, Yamano K, Simpson RJ, Taoka M, Yamauchi Y, Isobe T, Takahashi N.

Sci Rep. 2017 Aug 9;7(1):7709. doi: 10.1038/s41598-017-06953-y.

20.

Pick's disease with neuronal four-repeat tau accumulation in the basal ganglia, brain stem nuclei and cerebellum.

Ikeda C, Yokota O, Miki T, Takenoshita S, Ishizu H, Mori Y, Yamazaki K, Ozaki Y, Ueno SI, Ishihara T, Hasegawa M, Terada S, Yamada N.

Neuropathology. 2017 Dec;37(6):544-559. doi: 10.1111/neup.12394. Epub 2017 Jul 9.

PMID:
28691164

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