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Items: 18


Short-term LPS induces aortic valve thickening in ApoE*3Leiden mice.

van Broekhoven A, Krijnen PAJ, Fuijkschot WW, Morrison MC, Zethof IPA, van Wieringen WN, Smulders YM, Niessen HWM, Vonk ABA.

Eur J Clin Invest. 2019 Apr 23:e13121. doi: 10.1111/eci.13121. [Epub ahead of print]


Diet-Independent Correlations between Bacteria and Dysfunction of Gut, Adipose Tissue, and Liver: A Comprehensive Microbiota Analysis in Feces and Mucosa of the Ileum and Colon in Obese Mice with NAFLD.

Gart E, Souto Lima E, Schuren F, de Ruiter CGF, Attema J, Verschuren L, Keijer J, Salic K, Morrison MC, Kleemann R.

Int J Mol Sci. 2018 Dec 20;20(1). pii: E1. doi: 10.3390/ijms20010001.


Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice.

Morrison MC, Verschuren L, Salic K, Verheij J, Menke A, Wielinga PY, Iruarrizaga-Lejarreta M, Gole L, Yu WM, Turner S, Caspers MPM, Martínez-Arranz I, Pieterman E, Stoop R, van Koppen A, van den Hoek AM, Mato JM, Hanemaaijer R, Alonso C, Kleemann R.

Hepatol Commun. 2018 Oct 29;2(12):1513-1532. doi: 10.1002/hep4.1270. eCollection 2018 Dec.


StemBell therapy stabilizes atherosclerotic plaques after myocardial infarction.

Woudstra L, Meinster E, VAN Haren L, Kay AM, Koopman M, Belien JAM, Morrison MC, VAN Rossum AC, Helder MN, Juffermans LJM, Niessen HWM, Krijnen PAJ.

Cytotherapy. 2018 Sep;20(9):1143-1154. doi: 10.1016/j.jcyt.2018.05.006. Epub 2018 Aug 12.


Key Inflammatory Processes in Human NASH Are Reflected in Ldlr-/-.Leiden Mice: A Translational Gene Profiling Study.

Morrison MC, Kleemann R, van Koppen A, Hanemaaijer R, Verschuren L.

Front Physiol. 2018 Feb 23;9:132. doi: 10.3389/fphys.2018.00132. eCollection 2018.


CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice.

Zimmer M, Bista P, Benson EL, Lee DY, Liu F, Picarella D, Vega RB, Vu CB, Yeager M, Ding M, Liang G, Horton JD, Kleemann R, Kooistra T, Morrison MC, Wielinga PY, Milne JC, Jirousek MR, Nichols AJ.

Hepatol Commun. 2017 May 12;1(4):311-325. doi: 10.1002/hep4.1042. eCollection 2017 Jun.


Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model.

van Koppen A, Verschuren L, van den Hoek AM, Verheij J, Morrison MC, Li K, Nagabukuro H, Costessi A, Caspers MPM, van den Broek TJ, Sagartz J, Kluft C, Beysen C, Emson C, van Gool AJ, Goldschmeding R, Stoop R, Bobeldijk-Pastorova I, Turner SM, Hanauer G, Hanemaaijer R.

Cell Mol Gastroenterol Hepatol. 2017 Oct 14;5(1):83-98.e10. doi: 10.1016/j.jcmgh.2017.10.001. eCollection 2018.


LPS-Induced Systemic Inflammation Does Not Alter Atherosclerotic Plaque Area or Inflammation in APOE3*LEIDEN Mice in the Early Phase Up to 15 Days.

Fuijkschot WW, Morrison MC, Zethof IPA, Krijnen PAJ, Kleemann R, Niessen HWM, Smulders YM.

Shock. 2018 Sep;50(3):360-365. doi: 10.1097/SHK.0000000000001026.


A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice.

Schoemaker MH, Kleemann R, Morrison MC, Verheij J, Salic K, van Tol EAF, Kooistra T, Wielinga PY.

PLoS One. 2017 Jul 5;12(7):e0180648. doi: 10.1371/journal.pone.0180648. eCollection 2017.


Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

Morrison MC, Yakala GK, Liang W, Wielinga PY, Salic K, van Koppen A, Tomar T, Kleemann R, Heeringa P, Kooistra T.

Sci Rep. 2017 Jun 6;7(1):2915. doi: 10.1038/s41598-017-02444-2.


Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice.

Fuijkschot WW, Morrison MC, van der Linden R, Krijnen PAJ, Zethof IPA, Theyse LFH, Kleemann R, Niessen HWM, Smulders YM.

Atherosclerosis. 2016 Dec;255:164-170. doi: 10.1016/j.atherosclerosis.2016.07.909. Epub 2016 Oct 28.


Reduction of obesity-associated white adipose tissue inflammation by rosiglitazone is associated with reduced non-alcoholic fatty liver disease in LDLr-deficient mice.

Mulder P, Morrison MC, Verschuren L, Liang W, van Bockel JH, Kooistra T, Wielinga PY, Kleemann R.

Sci Rep. 2016 Aug 22;6:31542. doi: 10.1038/srep31542.


Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity.

van der Heijden RA, Morrison MC, Sheedfar F, Mulder P, Schreurs M, Hommelberg PP, Hofker MH, Schalkwijk C, Kleemann R, Tietge UJ, Koonen DP, Heeringa P.

Mediators Inflamm. 2016;2016:2042107. doi: 10.1155/2016/2042107. Epub 2016 Jun 6.


Resolvin E1 attenuates atherosclerosis in absence of cholesterol-lowering effects and on top of atorvastatin.

Salic K, Morrison MC, Verschuren L, Wielinga PY, Wu L, Kleemann R, Gjorstrup P, Kooistra T.

Atherosclerosis. 2016 Jul;250:158-65. doi: 10.1016/j.atherosclerosis.2016.05.001. Epub 2016 May 2.


Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil.

Morrison MC, Mulder P, Stavro PM, Suárez M, Arola-Arnal A, van Duyvenvoorde W, Kooistra T, Wielinga PY, Kleemann R.

PLoS One. 2015 Sep 25;10(9):e0139196. doi: 10.1371/journal.pone.0139196. eCollection 2015.


High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice.

van der Heijden RA, Sheedfar F, Morrison MC, Hommelberg PP, Kor D, Kloosterhuis NJ, Gruben N, Youssef SA, de Bruin A, Hofker MH, Kleemann R, Koonen DP, Heeringa P.

Aging (Albany NY). 2015 Apr;7(4):256-68.


Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice.

Morrison MC, Liang W, Mulder P, Verschuren L, Pieterman E, Toet K, Heeringa P, Wielinga PY, Kooistra T, Kleemann R.

J Hepatol. 2015 May;62(5):1180-6. doi: 10.1016/j.jhep.2014.12.011. Epub 2014 Dec 13.

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