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Items: 1 to 20 of 39

1.

Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins.

Latko M, Czyrek A, Porębska N, Kucińska M, Otlewski J, Zakrzewska M, Opaliński Ł.

Cells. 2019 May 14;8(5). pii: E455. doi: 10.3390/cells8050455. Review.

2.

Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling.

Zakrzewska M, Opalinski L, Haugsten EM, Otlewski J, Wiedlocha A.

Int J Mol Sci. 2019 Apr 12;20(8). pii: E1826. doi: 10.3390/ijms20081826.

3.

Targeting Cellular Trafficking of Fibroblast Growth Factor Receptors as a Strategy for Selective Cancer Treatment.

Porębska N, Latko M, Kucińska M, Zakrzewska M, Otlewski J, Opaliński Ł.

J Clin Med. 2018 Dec 20;8(1). pii: E7. doi: 10.3390/jcm8010007. Review.

4.

Specific Antibody Fragment Ligand Traps Blocking FGF1 Activity.

Chudzian J, Szlachcic A, Zakrzewska M, Czub M, Pustula M, Holak TA, Otlewski J.

Int J Mol Sci. 2018 Aug 21;19(9). pii: E2470. doi: 10.3390/ijms19092470.

5.

Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation.

Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, Otlewski J, Zakrzewska M.

J Mol Biol. 2018 Oct 19;430(21):4087-4101. doi: 10.1016/j.jmb.2018.08.004. Epub 2018 Aug 9.

6.

FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1.

Świderska KW, Szlachcic A, Opaliński Ł, Zakrzewska M, Otlewski J.

Int J Mol Sci. 2018 Jul 19;19(7). pii: E2098. doi: 10.3390/ijms19072098.

7.

Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors.

Krzyscik MA, Zakrzewska M, Sørensen V, Sokolowska-Wedzina A, Lobocki M, Swiderska KW, Krowarsch D, Wiedlocha A, Otlewski J.

ACS Omega. 2017 Jul 31;2(7):3792-3805. doi: 10.1021/acsomega.7b00116. Epub 2017 Jul 21.

8.

Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals.

Balek L, Buchtova M, Kunova Bosakova M, Varecha M, Foldynova-Trantirkova S, Gudernova I, Vesela I, Havlik J, Neburkova J, Turner S, Krzyscik MA, Zakrzewska M, Klimaschewski L, Claus P, Trantirek L, Cigler P, Krejci P.

Biomaterials. 2018 Sep;176:106-121. doi: 10.1016/j.biomaterials.2018.05.030. Epub 2018 May 21.

9.

High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1.

Opaliński Ł, Szymczyk J, Szczepara M, Kucińska M, Krowarsch D, Zakrzewska M, Otlewski J.

Int J Mol Sci. 2018 May 10;19(5). pii: E1435. doi: 10.3390/ijms19051435.

10.

Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity.

Opaliński Ł, Sokołowska-Wędzina A, Szczepara M, Zakrzewska M, Otlewski J.

Sci Rep. 2017 Aug 2;7(1):7121. doi: 10.1038/s41598-017-07479-z.

11.

The autoinhibitory function of D1 domain of FGFR1 goes beyond the inhibition of ligand binding.

Opalinski L, Szczepara M, Sokolowska-Wedzina A, Zakrzewska M, Otlewski J.

Int J Biochem Cell Biol. 2017 Aug;89:193-198. doi: 10.1016/j.biocel.2017.06.015. Epub 2017 Jun 23.

PMID:
28652212
12.

High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E via Cysteine Flanked by Basic Residues.

Lobocki M, Zakrzewska M, Szlachcic A, Krzyscik MA, Sokolowska-Wedzina A, Otlewski J.

Bioconjug Chem. 2017 Jul 19;28(7):1850-1858. doi: 10.1021/acs.bioconjchem.7b00158. Epub 2017 Jun 23.

PMID:
28598150
13.

High-Affinity Internalizing Human scFv-Fc Antibody for Targeting FGFR1-Overexpressing Lung Cancer.

Sokolowska-Wedzina A, Chodaczek G, Chudzian J, Borek A, Zakrzewska M, Otlewski J.

Mol Cancer Res. 2017 Aug;15(8):1040-1050. doi: 10.1158/1541-7786.MCR-16-0136. Epub 2017 May 8.

14.

Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy.

Szlachcic A, Zakrzewska M, Lobocki M, Jakimowicz P, Otlewski J.

Drug Des Devel Ther. 2016 Aug 9;10:2547-60. doi: 10.2147/DDDT.S105896. eCollection 2016.

15.

Identification of new FGF1 binding partners-Implications for its intracellular function.

Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J.

IUBMB Life. 2016 Mar;68(3):242-51. doi: 10.1002/iub.1480. Epub 2016 Feb 2.

16.

Orange protein from Desulfovibrio alaskensis G20: insights into the Mo-Cu cluster protein-assisted synthesis.

Carepo MS, Carreira C, Grazina R, Zakrzewska ME, Dolla A, Aubert C, Pauleta SR, Moura JJ, Moura I.

J Biol Inorg Chem. 2016 Mar;21(1):53-62. doi: 10.1007/s00775-015-1323-x. Epub 2016 Jan 9.

PMID:
26748795
17.

Instability restricts signaling of multiple fibroblast growth factors.

Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P.

Cell Mol Life Sci. 2015 Jun;72(12):2445-59. doi: 10.1007/s00018-015-1856-8. Epub 2015 Feb 18.

PMID:
25854632
18.

Efficient production and purification of extracellular domain of human FGFR-Fc fusion proteins from Chinese hamster ovary cells.

Sokolowska-Wedzina A, Borek A, Chudzian J, Jakimowicz P, Zakrzewska M, Otlewski J.

Protein Expr Purif. 2014 Jul;99:50-7. doi: 10.1016/j.pep.2014.03.012. Epub 2014 Apr 13.

PMID:
24727156
19.

Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1).

Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A.

PLoS One. 2014 Mar 4;9(3):e90687. doi: 10.1371/journal.pone.0090687. eCollection 2014.

20.

Protease resistant variants of FGF1 with prolonged biological activity.

Kobielak A, Zakrzewska M, Kostas M, Jakimowicz P, Otlewski J, Krowarsch D.

Protein Pept Lett. 2014 May;21(5):434-43.

PMID:
24304385

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