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Items: 1 to 20 of 81


Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences.

Melková K, Zapletal V, Narasimhan S, Jansen S, Hritz J, Škrabana R, Zweckstetter M, Ringkjøbing Jensen M, Blackledge M, Žídek L.

Biomolecules. 2019 Mar 16;9(3). pii: E105. doi: 10.3390/biom9030105. Review.


Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.

Desfosses A, Milles S, Jensen MR, Guseva S, Colletier JP, Maurin D, Schoehn G, Gutsche I, Ruigrok RWH, Blackledge M.

Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 201816417. doi: 10.1073/pnas.1816417116. [Epub ahead of print]


Characterization of intrinsically disordered proteins and their dynamic complexes: From in vitro to cell-like environments.

Milles S, Salvi N, Blackledge M, Jensen MR.

Prog Nucl Magn Reson Spectrosc. 2018 Dec;109:79-100. doi: 10.1016/j.pnmrs.2018.07.001. Epub 2018 Jul 31. Review.


Elucidating binding mechanisms and dynamics of intrinsically disordered protein complexes using NMR spectroscopy.

Schneider R, Blackledge M, Jensen MR.

Curr Opin Struct Biol. 2018 Oct 10;54:10-18. doi: 10.1016/ [Epub ahead of print] Review.


An ultraweak interaction in the intrinsically disordered replication machinery is essential for measles virus function.

Milles S, Jensen MR, Lazert C, Guseva S, Ivashchenko S, Communie G, Maurin D, Gerlier D, Ruigrok RWH, Blackledge M.

Sci Adv. 2018 Aug 22;4(8):eaat7778. doi: 10.1126/sciadv.aat7778. eCollection 2018 Aug.


Structural basis of the bacteriophage TP901-1 CI repressor dimerization and interaction with DNA.

Rasmussen KK, Varming AK, Schmidt SN, Frandsen KEH, Thulstrup PW, Jensen MR, Lo Leggio L.

FEBS Lett. 2018 May;592(10):1738-1750. doi: 10.1002/1873-3468.13060. Epub 2018 May 13.


Characterizing Protein-Protein Interactions Using Solution NMR Spectroscopy.

Ortega-Roldan JL, Blackledge M, Jensen MR.

Methods Mol Biol. 2018;1764:73-85. doi: 10.1007/978-1-4939-7759-8_5.


Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy.

Delaforge E, Kragelj J, Tengo L, Palencia A, Milles S, Bouvignies G, Salvi N, Blackledge M, Jensen MR.

J Am Chem Soc. 2018 Jan 24;140(3):1148-1158. doi: 10.1021/jacs.7b12407. Epub 2018 Jan 11.


Structural analysis of the complex between influenza B nucleoprotein and human importin-α.

Labaronne A, Milles S, Donchet A, Jensen MR, Blackledge M, Bourhis JM, Ruigrok RWH, Crépin T.

Sci Rep. 2017 Dec 7;7(1):17164. doi: 10.1038/s41598-017-17458-z.


Self-association of a highly charged arginine-rich cell-penetrating peptide.

Tesei G, Vazdar M, Jensen MR, Cragnell C, Mason PE, Heyda J, Skepö M, Jungwirth P, Lund M.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11428-11433. doi: 10.1073/pnas.1712078114. Epub 2017 Oct 11.


Structural and Kinetic Characterization of the Intrinsically Disordered Protein SeV NTAIL through Enhanced Sampling Simulations.

Bernetti M, Masetti M, Pietrucci F, Blackledge M, Jensen MR, Recanatini M, Mollica L, Cavalli A.

J Phys Chem B. 2017 Oct 19;121(41):9572-9582. doi: 10.1021/acs.jpcb.7b08925. Epub 2017 Oct 4.


The LC8 Recognition Motif Preferentially Samples Polyproline II Structure in Its Free State.

Morgan JL, Jensen MR, Ozenne V, Blackledge M, Barbar E.

Biochemistry. 2017 Sep 5;56(35):4656-4666. doi: 10.1021/acs.biochem.7b00552. Epub 2017 Aug 23.


Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7.

Desravines DC, Serna Martin I, Schneider R, Mas PJ, Aleksandrova N, Jensen MR, Blackledge M, Hart DJ.

Sci Rep. 2017 Jun 16;7(1):3678. doi: 10.1038/s41598-017-03718-5.


Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).

Sukackaite R, Cornacchia D, Jensen MR, Mas PJ, Blackledge M, Enervald E, Duan G, Auchynnikava T, Köhn M, Hart DJ, Buonomo SBC.

Sci Rep. 2017 May 18;7(1):2119. doi: 10.1038/s41598-017-01910-1.


A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.

Whitley MJ, Xi Z, Bartko JC, Jensen MR, Blackledge M, Gronenborn AM.

Biophys J. 2017 Mar 28;112(6):1135-1146. doi: 10.1016/j.bpj.2017.02.010.


Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.

Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, Blackledge M.

Front Mol Biosci. 2016 Sep 13;3:54. doi: 10.3389/fmolb.2016.00054. eCollection 2016. Review.


Binding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and Experiment.

Mollica L, Bessa LM, Hanoulle X, Jensen MR, Blackledge M, Schneider R.

Front Mol Biosci. 2016 Sep 9;3:52. doi: 10.3389/fmolb.2016.00052. eCollection 2016. Review.


Structural and dynamics studies of a truncated variant of CI repressor from bacteriophage TP901-1.

Rasmussen KK, Frandsen KE, Boeri Erba E, Pedersen M, Varming AK, Hammer K, Kilstrup M, Thulstrup PW, Blackledge M, Jensen MR, Lo Leggio L.

Sci Rep. 2016 Jul 12;6:29574. doi: 10.1038/srep29574.


Self-Assembly of Measles Virus Nucleocapsid-like Particles: Kinetics and RNA Sequence Dependence.

Milles S, Jensen MR, Communie G, Maurin D, Schoehn G, Ruigrok RW, Blackledge M.

Angew Chem Int Ed Engl. 2016 Aug 1;55(32):9356-60. doi: 10.1002/anie.201602619. Epub 2016 Jun 6.


Identification of Dynamic Modes in an Intrinsically Disordered Protein Using Temperature-Dependent NMR Relaxation.

Abyzov A, Salvi N, Schneider R, Maurin D, Ruigrok RW, Jensen MR, Blackledge M.

J Am Chem Soc. 2016 May 18;138(19):6240-51. doi: 10.1021/jacs.6b02424. Epub 2016 May 6.


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