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Items: 1 to 20 of 29


Regional discrepancies in spatiotemporal variations and driving forces of open crop residue burning emissions in China.

Xu Y, Huang Z, Jia G, Fan M, Cheng L, Chen L, Shao M, Zheng J.

Sci Total Environ. 2019 Jun 25;671:536-547. doi: 10.1016/j.scitotenv.2019.03.199. Epub 2019 Mar 15.


Assessment of satellite-estimated near-surface sulfate and nitrate concentrations and their precursor emissions over China from 2006 to 2014.

Si Y, Yu C, Zhang L, Zhu W, Cai K, Cheng L, Chen L, Li S.

Sci Total Environ. 2019 Jun 15;669:362-376. doi: 10.1016/j.scitotenv.2019.02.180. Epub 2019 Mar 5.


Estimating PM2.5 Concentrations Based on MODIS AOD and NAQPMS Data over Beijing⁻Tianjin⁻Hebei.

Wang Q, Zeng Q, Tao J, Sun L, Zhang L, Gu T, Wang Z, Chen L.

Sensors (Basel). 2019 Mar 9;19(5). pii: E1207. doi: 10.3390/s19051207.


ImmunoPET imaging to assess target engagement: Experience from 89Zr-anti-HER3 mAb (GSK2849330) in patients with solid tumors.

Menke-van der Houven van Oordt CW, McGeoch A, Bergstrom M, McSherry I, Smith DA, Cleveland M, Al-Azzam W, Chen L, Verheul H, Hoekstra OS, Vugts DJ, Freedman I, Huisman M, Matheny C, van Dongen G, Zhang S.

J Nucl Med. 2019 Feb 7. pii: jnumed.118.214726. doi: 10.2967/jnumed.118.214726. [Epub ahead of print]


Satellite-Based Estimation of Hourly PM2.5 Concentrations Using a Vertical-Humidity Correction Method from Himawari-AOD in Hebei.

Zeng Q, Chen L, Zhu H, Wang Z, Wang X, Zhang L, Gu T, Zhu G, Zhang AY.

Sensors (Basel). 2018 Oct 14;18(10). pii: E3456. doi: 10.3390/s18103456.


Assessment of Retrieved N₂O, NO₂, and HF Profiles from the Atmospheric Infrared Ultraspectral Sounder Based on Simulated Spectra.

Wang H, Li X, Xu J, Zhang X, Ge S, Chen L, Wang Y, Zhu S, Miao J, Si Y.

Sensors (Basel). 2018 Jul 9;18(7). pii: E2209. doi: 10.3390/s18072209.


Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance.

Kenny JR, Ramsden D, Buckley DB, Dallas S, Fung C, Mohutsky M, Einolf HJ, Chen L, Dekeyser JG, Fitzgerald M, Goosen TC, Siu YA, Walsky RL, Zhang G, Tweedie D, Hariparsad N.

Drug Metab Dispos. 2018 Sep;46(9):1285-1303. doi: 10.1124/dmd.118.081927. Epub 2018 Jun 29.


Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control.

Hariparsad N, Ramsden D, Palamanda J, Dekeyser JG, Fahmi OA, Kenny JR, Einolf H, Mohutsky M, Pardon M, Siu YA, Chen L, Sinz M, Jones B, Walsky R, Dallas S, Balani SK, Zhang G, Buckley D, Tweedie D.

Drug Metab Dispos. 2017 Oct;45(10):1049-1059. doi: 10.1124/dmd.116.074567. Epub 2017 Jun 23.


Prediction of the Transporter-Mediated Drug-Drug Interaction Potential of Dabrafenib and Its Major Circulating Metabolites.

Ellens H, Johnson M, Lawrence SK, Watson C, Chen L, Richards-Peterson LE.

Drug Metab Dispos. 2017 Jun;45(6):646-656. doi: 10.1124/dmd.116.073932. Epub 2017 Mar 20.


DiffusionKit: A light one-stop solution for diffusion MRI data analysis.

Xie S, Chen L, Zuo N, Jiang T.

J Neurosci Methods. 2016 Nov 1;273:107-119. doi: 10.1016/j.jneumeth.2016.08.011. Epub 2016 Aug 24.


Evaluation of CYP2B6 Induction and Prediction of Clinical Drug-Drug Interactions: Considerations from the IQ Consortium Induction Working Group-An Industry Perspective.

Fahmi OA, Shebley M, Palamanda J, Sinz MW, Ramsden D, Einolf HJ, Chen L, Wang H.

Drug Metab Dispos. 2016 Oct;44(10):1720-30. doi: 10.1124/dmd.116.071076. Epub 2016 Jul 15.


The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture.

Fan L, Li H, Zhuo J, Zhang Y, Wang J, Chen L, Yang Z, Chu C, Xie S, Laird AR, Fox PT, Eickhoff SB, Yu C, Jiang T.

Cereb Cortex. 2016 Aug;26(8):3508-26. doi: 10.1093/cercor/bhw157. Epub 2016 May 26.


Spatiotemporal analysis for the effect of ambient particulate matter on cause-specific respiratory mortality in Beijing, China.

Wang X, Guo Y, Li G, Zhang Y, Westerdahl D, Jin X, Pan X, Chen L.

Environ Sci Pollut Res Int. 2016 Jun;23(11):10946-56. doi: 10.1007/s11356-016-6273-5. Epub 2016 Feb 22.


Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model.

Dallas S, Salphati L, Gomez-Zepeda D, Wanek T, Chen L, Chu X, Kunta J, Mezler M, Menet MC, Chasseigneaux S, Declèves X, Langer O, Pierre E, DiLoreto K, Hoft C, Laplanche L, Pang J, Pereira T, Andonian C, Simic D, Rode A, Yabut J, Zhang X, Scheer N.

Mol Pharmacol. 2016 May;89(5):492-504. doi: 10.1124/mol.115.102079. Epub 2016 Feb 18.


APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals.

You L, Wu J, Feng Y, Fu Y, Guo Y, Long L, Zhang H, Luan Y, Tian P, Chen L, Huang G, Huang S, Li Y, Li J, Chen C, Zhang Y, Chen S, Xu A.

Nucleic Acids Res. 2015 Jan;43(Database issue):D59-67. doi: 10.1093/nar/gku1076. Epub 2014 Nov 6.


Statistical evaluation of the feasibility of satellite-retrieved cloud parameters as indicators of PM2.5 levels.

Yu C, Di Girolamo L, Chen L, Zhang X, Liu Y.

J Expo Sci Environ Epidemiol. 2015 Sep-Oct;25(5):457-66. doi: 10.1038/jes.2014.49. Epub 2014 Jul 23.


Investigation of metabolism and disposition of GSK1322322, a peptidase deformylase inhibitor, in healthy humans using the entero-test for biliary sampling.

Mamaril-Fishman D, Zhu J, Lin M, Felgate C, Jones L, Stump P, Pierre E, Bowen C, Naderer O, Dumont E, Patel P, Gorycki PD, Wen B, Chen L, Deng Y.

Drug Metab Dispos. 2014 Aug;42(8):1314-25. doi: 10.1124/dmd.114.058420. Epub 2014 May 28.


Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

Salphati L, Chu X, Chen L, Prasad B, Dallas S, Evers R, Mamaril-Fishman D, Geier EG, Kehler J, Kunta J, Mezler M, Laplanche L, Pang J, Rode A, Soars MG, Unadkat JD, van Waterschoot RA, Yabut J, Schinkel AH, Scheer N.

Drug Metab Dispos. 2014 Aug;42(8):1301-13. doi: 10.1124/dmd.114.057976. Epub 2014 May 22.


Penetration of GSK1322322 into epithelial lining fluid and alveolar macrophages as determined by bronchoalveolar lavage.

Naderer OJ, Rodvold KA, Jones LS, Zhu JZ, Bowen CL, Chen L, Dumont E.

Antimicrob Agents Chemother. 2014;58(1):419-23. doi: 10.1128/AAC.01836-13. Epub 2013 Nov 4.

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