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Items: 1 to 20 of 28


p53 at the Crossroads between Different Types of HDAC Inhibitor-Mediated Cancer Cell Death.

Mrakovcic M, Kleinheinz J, Fröhlich LF.

Int J Mol Sci. 2019 May 15;20(10). pii: E2415. doi: 10.3390/ijms20102415. Review.


Micrornas at the Interface between Osteogenesis and Angiogenesis as Targets for Bone Regeneration.

Fröhlich LF.

Cells. 2019 Feb 3;8(2). pii: E121. doi: 10.3390/cells8020121. Review.


Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53.

Mrakovcic M, Bohner L, Hanisch M, Fröhlich LF.

Int J Mol Sci. 2018 Dec 8;19(12). pii: E3952. doi: 10.3390/ijms19123952. Review.


High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype.

Golob-Schwarzl N, Bettermann K, Mehta AK, Kessler SM, Unterluggauer J, Krassnig S, Kojima K, Chen X, Hoshida Y, Bardeesy NM, Müller H, Svendova V, Schimek MG, Diwoky C, Lipfert A, Mahajan V, Stumptner C, Thüringer A, Fröhlich LF, Stojakovic T, Nilsson KPR, Kolbe T, Rülicke T, Magin TM, Strnad P, Kiemer AK, Moriggl R, Haybaeck J.

Transl Oncol. 2019 Feb;12(2):256-268. doi: 10.1016/j.tranon.2018.10.010. Epub 2018 Nov 12.


Myositis ossificans traumatica of the masticatory muscles: etiology, diagnosis and treatment.

Hanisch M, Hanisch L, Fröhlich LF, Werkmeister R, Bohner L, Kleinheinz J.

Head Face Med. 2018 Oct 29;14(1):23. doi: 10.1186/s13005-018-0180-6. Review.


p53-Mediated Molecular Control of Autophagy in Tumor Cells.

Mrakovcic M, Fröhlich LF.

Biomolecules. 2018 Mar 21;8(2). pii: E14. doi: 10.3390/biom8020014. Review.


Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53.

Mrakovcic M, Kleinheinz J, Fröhlich LF.

Int J Mol Sci. 2017 Aug 31;18(9). pii: E1883. doi: 10.3390/ijms18091883. Review.


Ectopic third molars in the sigmoid notch: etiology, diagnostic imaging and treatment options.

Hanisch M, Fröhlich LF, Kleinheinz J.

Head Face Med. 2016 Dec 6;12(1):36.


Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway.

Fröhlich LF, Mrakovcic M, Smole C, Zatloukal K.

Cancer Cell Int. 2016 Sep 6;16(1):68. doi: 10.1186/s12935-016-0343-0. eCollection 2016.


p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies.

Lahiri P, Schmidt V, Smole C, Kufferath I, Denk H, Strnad P, Rülicke T, Fröhlich LF, Zatloukal K.

PLoS One. 2016 Aug 15;11(8):e0161083. doi: 10.1371/journal.pone.0161083. eCollection 2016.


Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.

Yang H, Ni HM, Guo F, Ding Y, Shi YH, Lahiri P, Fröhlich LF, Rülicke T, Smole C, Schmidt VC, Zatloukal K, Cui Y, Komatsu M, Fan J, Ding WX.

J Biol Chem. 2016 Sep 2;291(36):18663-74. doi: 10.1074/jbc.M116.739821. Epub 2016 Jun 20.


Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells.

Fröhlich LF, Mrakovcic M, Smole C, Lahiri P, Zatloukal K.

PLoS One. 2014 Mar 11;9(3):e91558. doi: 10.1371/journal.pone.0091558. eCollection 2014.


Controlling complexity: the clinical relevance of mouse complex genetics.

Schughart K, Libert C; SYSGENET consortium, Kas MJ.

Eur J Hum Genet. 2013 Nov;21(11):1191-6. doi: 10.1038/ejhg.2013.79. Epub 2013 May 1. Review.


Assessment of long-term effects of nanoparticles in a microcarrier cell culture system.

Mrakovcic M, Absenger M, Riedl R, Smole C, Roblegg E, Fröhlich LF, Fröhlich E.

PLoS One. 2013;8(2):e56791. doi: 10.1371/journal.pone.0056791. Epub 2013 Feb 14.


Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.

Fernández-Rebollo E, Maeda A, Reyes M, Turan S, Fröhlich LF, Plagge A, Kelsey G, Jüppner H, Bastepe M.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6638-43. doi: 10.1073/pnas.1117608109. Epub 2012 Apr 10.


miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.

Senanayake U, Das S, Vesely P, Alzoughbi W, Fröhlich LF, Chowdhury P, Leuschner I, Hoefler G, Guertl B.

Carcinogenesis. 2012 May;33(5):1014-21. doi: 10.1093/carcin/bgs126. Epub 2012 Mar 19.


Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo.

Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Fröhlich LF, Bastepe M.

Endocrinology. 2011 Apr;152(4):1222-33. doi: 10.1210/en.2010-1034. Epub 2011 Feb 8.


Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.

Motta JP, Magne L, Descamps D, Rolland C, Squarzoni-Dale C, Rousset P, Martin L, Cenac N, Balloy V, Huerre M, Fröhlich LF, Jenne D, Wartelle J, Belaaouaj A, Mas E, Vinel JP, Alric L, Chignard M, Vergnolle N, Sallenave JM.

Gastroenterology. 2011 Apr;140(4):1272-82. doi: 10.1053/j.gastro.2010.12.050. Epub 2011 Jan 1.


Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib.

Fröhlich LF, Mrakovcic M, Steinborn R, Chung UI, Bastepe M, Jüppner H.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9275-80. doi: 10.1073/pnas.0910224107. Epub 2010 Apr 28.

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