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Toll-like Receptor 7 Deficiency Promotes Survival and Reduces Adverse Left Ventricular Remodeling After Myocardial Infarction.

de Kleijn DPV, Chong SY, Wang X, Yatim SMJM, Fairhurst AM, Vernooij F, Zharkova O, Chan M, Foo RSY, Timmers L, Lam CSP, Wang JW.

Cardiovasc Res. 2019 Mar 4. pii: cvz057. doi: 10.1093/cvr/cvz057. [Epub ahead of print]


One-year clinical outcomes of patients treated with polymer-free amphilimus-eluting stents or zotarolimus-eluting stents: A propensity-score adjusted analysis.

Rozemeijer R, van Muiden IG, Koudstaal S, Leenders GE, Timmers L, Rittersma SZ, Kraaijeveld AO, Doevendans PA, Voskuil M, Stella PR.

Catheter Cardiovasc Interv. 2019 Jan 2. doi: 10.1002/ccd.28041. [Epub ahead of print]


Randomized All-Comers Evaluation of a Permanent Polymer Zotarolimus-Eluting Stent Versus a Polymer-Free Amphilimus-Eluting Stent.

Rozemeijer R, Stein M, Voskuil M, van den Bor R, Frambach P, Pereira B, Koudstaal S, Leenders GE, Timmers L, Rittersma SZ, Kraaijeveld AO, Agostoni P, Roes KC, Doevendans PA, Stella PR; ReCre8 Study Investigators.

Circulation. 2019 Jan 2;139(1):67-77. doi: 10.1161/CIRCULATIONAHA.118.037707.


Renin and aldosterone are not associated with vulnerable plaque characteristics in patients with carotid artery disease.

Hillaert MA, den Ruijter HM, Hoefer IE, Lentjes EG, de Borst GJ, de Vries JPM, Doevendans PA, Pasterkamp G, Timmers L.

J Vasc Surg. 2018 Jul;68(1):128-135. doi: 10.1016/j.jvs.2017.05.117. Epub 2018 Mar 13.


Subadventitial stenting around occluded stents: A bailout technique to recanalize in-stent chronic total occlusions.

Azzalini L, Karatasakis A, Spratt JC, Tajti P, Riley RF, Ybarra LF, Schumacher SP, Benincasa S, Bellini B, Candilio L, Mitomo S, Henriksen P, Hidalgo F, Timmers L, Kraaijeveld AO, Agostoni P, Roy J, Ramsay DR, Weaver JC, Knaapen P, Nap A, Starcevic B, Ojeda S, Pan M, Alaswad K, Lombardi WL, Carlino M, Brilakis ES, Colombo A, Rinfret S, Mashayekhi K.

Catheter Cardiovasc Interv. 2018 Sep 1;92(3):466-476. doi: 10.1002/ccd.27472. Epub 2018 Jan 4.


Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles.

Wang JW, Zhang YN, Sze SK, van de Weg SM, Vernooij F, Schoneveld AH, Tan SH, Versteeg HH, Timmers L, Lam CSP, de Kleijn DPV.

Int J Mol Sci. 2017 Dec 29;19(1). pii: E94. doi: 10.3390/ijms19010094.


Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice.

Ellenbroek GHJM, de Haan JJ, van Klarenbosch BR, Brans MAD, van de Weg SM, Smeets MB, de Jong S, Arslan F, Timmers L, Goumans MTH, Hoefer IE, Doevendans PA, Pasterkamp G, Meyaard L, de Jager SCA.

Sci Rep. 2017 Dec 21;7(1):18039. doi: 10.1038/s41598-017-13678-5.


Clinical outcomes of complex real-world diabetic patients treated with amphilimus sirolimus-eluting stents or zotarolimus-eluting stents: A single-center registry.

Rozemeijer R, Benedetto D, Kraaijeveld AO, Voskuil M, Stein M, Timmers L, Rittersma SZ, Agostoni P, Doevendans PA, Stella PR.

Cardiovasc Revasc Med. 2018 Jul;19(5 Pt A):521-525. doi: 10.1016/j.carrev.2017.10.011. Epub 2017 Oct 26.


Mechanisms of Very Late Bioresorbable Scaffold Thrombosis: The INVEST Registry.

Yamaji K, Ueki Y, Souteyrand G, Daemen J, Wiebe J, Nef H, Adriaenssens T, Loh JP, Lattuca B, Wykrzykowska JJ, Gomez-Lara J, Timmers L, Motreff P, Hoppmann P, Abdel-Wahab M, Byrne RA, Meincke F, Boeder N, Honton B, O'Sullivan CJ, Ielasi A, Delarche N, Christ G, Lee JKT, Lee M, Amabile N, Karagiannis A, Windecker S, Räber L.

J Am Coll Cardiol. 2017 Nov 7;70(19):2330-2344. doi: 10.1016/j.jacc.2017.09.014.


Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload.

Wang JW, Fontes MSC, Wang X, Chong SY, Kessler EL, Zhang YN, de Haan JJ, Arslan F, de Jager SCA, Timmers L, van Veen TAB, Lam CSP, Kleijn DPV.

Sci Rep. 2017 Aug 23;7(1):9193. doi: 10.1038/s41598-017-09451-3.


Retrograde Chronic Total Occlusion Percutaneous Coronary Intervention Through Ipsilateral Collateral Channels: A Multicenter Registry.

Azzalini L, Agostoni P, Benincasa S, Knaapen P, Schumacher SP, Dens J, Maeremans J, Kraaijeveld AO, Timmers L, Behnes M, Akin I, Toma A, Neumann FJ, Colombo A, Carlino M, Mashayekhi K.

JACC Cardiovasc Interv. 2017 Aug 14;10(15):1489-1497. doi: 10.1016/j.jcin.2017.06.002.


Sex-Based Differences in the Performance of the HEART Score in Patients Presenting to the Emergency Department With Acute Chest Pain.

Bank IEM, de Hoog VC, de Kleijn DPV, Pasterkamp G, Doevendans PA, den Ruijter HM, Dalmeijer G, Wildbergh TX, Mosterd A, Timmers L.

J Am Heart Assoc. 2017 Jun 21;6(6). pii: e005373. doi: 10.1161/JAHA.116.005373.


Rationale and design of amphilimus sirolimus-eluting stents versus zotarolimus-eluting stents in all-comers requiring percutaneous coronary intervention (ReCre8): A multicenter randomized clinical trial.

Rozemeijer R, Stein M, Frambach P, Voskuil M, Kraaijeveld AO, Rodríguez-Olivares R, Timmers L, Pereira B, Rittersma SZ, Agostoni P, Doevendans PA, Stella PR.

Catheter Cardiovasc Interv. 2018 Feb 15;91(3):410-416. doi: 10.1002/ccd.27142. Epub 2017 May 22.


Radiofrequency Ablation of the Atherosclerotic Plaque: a Proof of Concept Study in an Atherosclerotic Model.

Ellenbroek GHJM, van Hout GPJ, de Jager SCA, Timmers L, Vink A, Goldschmeding R, van der Kraak P, Pasterkamp G, Hoefer IE, Doevendans PA, Appelman Y.

J Cardiovasc Transl Res. 2017 Apr;10(2):221-232. doi: 10.1007/s12265-017-9743-3. Epub 2017 Mar 31.


HEART score performance in Asian and Caucasian patients presenting to the emergency department with suspected acute coronary syndrome.

de Hoog VC, Lim SH, Bank IE, Gijsberts CM, Ibrahim IB, Kuan WS, Ooi SB, Chua TS, Tai ES, Gao F, Pasterkamp G, den Ruijter HM, Doevendans PA, Wildbergh TX, Mosterd A, Richards AM, de Kleijn DP, Timmers L.

Eur Heart J Acute Cardiovasc Care. 2018 Oct;7(7):591-601. doi: 10.1177/2048872617700870. Epub 2017 Mar 31.


Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness.

Ellenbroek GH, van Puijvelde GH, Anas AA, Bot M, Asbach M, Schoneveld A, van Santbrink PJ, Foks AC, Timmers L, Doevendans PA, Pasterkamp G, Hoefer IE, van der Poll T, Kuiper J, de Jager SC.

Sci Rep. 2017 Feb 16;7:42688. doi: 10.1038/srep42688.


Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction.

Ellenbroek GH, van Hout GP, Timmers L, Doevendans PA, Pasterkamp G, Hoefer IE.

J Vis Exp. 2016 Oct 14;(116). doi: 10.3791/54021.


No benefit of additional treatment with exenatide in patients with an acute myocardial infarction.

Roos ST, Timmers L, Biesbroek PS, Nijveldt R, Kamp O, van Rossum AC, van Hout GP, Stella PR, Doevendans PA, Knaapen P, Velthuis BK, van Royen N, Voskuil M, Nap A, Appelman Y.

Int J Cardiol. 2016 Oct 1;220:809-14. doi: 10.1016/j.ijcard.2016.06.283. Epub 2016 Jun 29.


Coronary aneurysm without malapposition after bioresorbable vascular scaffold implantation.

Timmers L, Lim YC, Tan HC, Low AF.

EuroIntervention. 2016 May 17;12(1):60. doi: 10.4244/EIJV12I1A10. No abstract available.


Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort.

Zhang YN, Vernooij F, Ibrahim I, Ooi S, Gijsberts CM, Schoneveld AH, Sen KW, den Ruijter HM, Timmers L, Richards AM, Jong CT, Mazlan I, Wang JW, Lam CS, de Kleijn DP.

PLoS One. 2016 Jan 28;11(1):e0148073. doi: 10.1371/journal.pone.0148073. eCollection 2016.

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