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Items: 15

1.

Continuous-flow protocol for the synthesis of enantiomerically pure intermediates of anti epilepsy and anti tuberculosis active pharmaceutical ingredients.

Aguiar RM, Leão RAC, Mata A, Cantillo D, Kappe CO, Miranda LSM, de Souza ROMA.

Org Biomol Chem. 2019 Feb 6;17(6):1552-1557. doi: 10.1039/c8ob03088j.

PMID:
30693360
2.

A Retrosynthesis Approach for Biocatalysis in Organic Synthesis.

de Souza ROMA, Miranda LSM, Bornscheuer UT.

Chemistry. 2017 Sep 7;23(50):12040-12063. doi: 10.1002/chem.201702235. Epub 2017 Jun 22. Review.

PMID:
28514518
3.

Functionalization of 2H-1,2,3-Triazole C-Nucleoside Template via N(2) Selective Arylation.

Lopes AB, Wagner P, de Souza RO, Germain NL, Uziel J, Bourguignon JJ, Schmitt M, Miranda LS.

J Org Chem. 2016 Jun 3;81(11):4540-9. doi: 10.1021/acs.joc.6b00323. Epub 2016 May 18.

PMID:
27166644
4.

Recent Advances in Applied Biocatalysis and Biotechnology.

de Souza RO, Miranda LS, Gutarra ML.

Biotechnol Adv. 2015 Sep-Oct;33(5):371. doi: 10.1016/j.biotechadv.2015.05.002. No abstract available.

PMID:
26087895
5.

Lipases: Valuable catalysts for dynamic kinetic resolutions.

de Miranda AS, Miranda LS, de Souza RO.

Biotechnol Adv. 2015 Sep-Oct;33(5):372-93. doi: 10.1016/j.biotechadv.2015.02.015. Epub 2015 Mar 17. Review.

PMID:
25795055
6.

Expanding the toolbox of asymmetric organocatalysis by continuous-flow process.

Finelli FG, Miranda LS, de Souza RO.

Chem Commun (Camb). 2015 Mar 4;51(18):3708-22. doi: 10.1039/c4cc08748h.

PMID:
25585518
7.

Active pharmaceutical ingredients for antiretroviral treatment in low- and middle-income countries: a survey.

Fortunak JM, de Souza RO, Kulkarni AA, King CL, Ellison T, Miranda LS.

Antivir Ther. 2014;19 Suppl 3:15-29. doi: 10.3851/IMP2897. Epub 2014 Oct 13.

8.

Gasoline from biomass through refinery-friendly carbohydrate-based bio-oil produced by ketalization.

Batalha N, da Silva AV, de Souza MO, da Costa BM, Gomes ES, Silva TC, Barros TG, Gonçalves ML, Caramão EB, dos Santos LR, Almeida MB, de Souza RO, Lam YL, Carvalho NM, Miranda LS, Pereira MM.

ChemSusChem. 2014 Jun;7(6):1627-36. doi: 10.1002/cssc.201301242. Epub 2014 Apr 17.

PMID:
24753476
9.

Continuous flow synthesis of α-halo ketones: essential building blocks of antiretroviral agents.

Pinho VD, Gutmann B, Miranda LS, de Souza RO, Kappe CO.

J Org Chem. 2014 Feb 21;79(4):1555-62. doi: 10.1021/jo402849z. Epub 2014 Feb 4.

10.

A three step continuous flow synthesis of the biaryl unit of the HIV protease inhibitor Atazanavir.

Dalla-Vechia L, Reichart B, Glasnov T, Miranda LS, Kappe CO, de Souza RO.

Org Biomol Chem. 2013 Oct 21;11(39):6806-13. doi: 10.1039/c3ob41464g.

PMID:
24175328
11.

Ethyl acetate as an acyl donor in the continuous flow kinetic resolution of (±)-1-phenylethylamine catalyzed by lipases.

de Miranda AS, Miranda LS, de Souza RO.

Org Biomol Chem. 2013 May 28;11(20):3332-6. doi: 10.1039/c3ob40437d.

PMID:
23558581
12.

The antinociceptive properties of the novel compound (±)-trans-4-hydroxy-6-propyl-1-oxocyclohexan-2-one in acute pain in mice.

Marinho BG, Miranda LS, da S Costa J, Leitão SG, Vasconcellos ML, Pereira VL, Fernandes PD.

Behav Pharmacol. 2013 Feb;24(1):10-9. doi: 10.1097/FBP.0b013e32835cf420.

PMID:
23263483
13.

On the mechanism of the Dakin-West reaction.

Dalla-Vechia L, Santos VG, Godoi MN, Cantillo D, Kappe CO, Eberlin MN, de Souza RO, Miranda LS.

Org Biomol Chem. 2012 Dec 7;10(45):9013-20. doi: 10.1039/c2ob26560e. Epub 2012 Oct 15.

PMID:
23070278
14.

Antinociceptive activity of (-)-(2S,6S)-(6-ethyl-tetrahydropyran-2-yl)-formic acid on acute pain in mice.

Marinho BG, Miranda LS, Meireles BA, Vasconcellos ML, Matheus ME, Pereira VL, Fernandes PD.

Behav Pharmacol. 2011 Sep;22(5-6):564-72. doi: 10.1097/FBP.0b013e3283474a1b.

PMID:
21562408
15.

Antinociceptive action of (+/-)-cis-(6-ethyl-tetrahydropyran-2-yl)-formic acid in mice.

Marinho BG, Miranda LS, Gomes NM, Matheus ME, Leitão SG, Vasconcellos ML, Fernandes PD.

Eur J Pharmacol. 2006 Nov 21;550(1-3):47-53. Epub 2006 Jul 5.

PMID:
17030031

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