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Fistein Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion via Affecting FAK, uPA and NF-ĸB Signaling Pathway In Vitro.

Chen JK, Peng SF, Lai KC, Liu HC, Huang YP, Lin CC, Huang AC, Chueh FS, Chung JG.

In Vivo. 2019 May-Jun;33(3):801-810. doi: 10.21873/invivo.11542.


Casticin Promotes Immune Responses, Enhances Macrophage and NK Cell Activities, and Increases Survival Rates of Leukemia BALB/c Mice.

Lai KC, Lu HF, Chen KB, Hsueh SC, Chung JG, Huang WW, Chen CC, Shang HS.

Am J Chin Med. 2019;47(1):223-236. doi: 10.1142/S0192415X19500113. Epub 2019 Jan 10.


Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL-60 cancer cell xenograft growth in vivo.

Hsiao YC, Peng SF, Lai KC, Liao CL, Huang YP, Lin CC, Lin ML, Liu KC, Tsai CC, Ma YS, Chung JG.

Environ Toxicol. 2019 Apr;34(4):443-456. doi: 10.1002/tox.22698. Epub 2019 Jan 7.


Maslinic Acid Enhances Immune Responses in Leukemic Mice Through Macrophage Phagocytosis and Natural Killer Cell Activities In Vivo.

Lai KC, Peng SF, Liu CC, Huang JY, Kuo JY, Cheng ZY, Wu RS, Lin CC, Chen JK, Chung JG.

In Vivo. 2019 Jan-Feb;33(1):65-73. doi: 10.21873/invivo.11440.


Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells.

Chou YC, Chang MY, Lee HT, Shen CC, Harnod T, Liang YJ, Wu RS, Lai KC, Hsu FT, Chung JG.

Molecules. 2018 Sep 10;23(9). pii: E2305. doi: 10.3390/molecules23092305.


Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro.

Liu JF, Lai KC, Peng SF, Maraming P, Huang YP, Huang AC, Chueh FS, Huang WW, Chung JG.

Molecules. 2018 Aug 13;23(8). pii: E2019. doi: 10.3390/molecules23082019.


Bisdemethoxycurcumin Suppresses Migration and Invasion of Human Cervical Cancer HeLa Cells via Inhibition of NF-ĸB, MMP-2 and -9 Pathways.

Liao CL, Chu YL, Lin HY, Chen CY, Hsu MJ, Liu KC, Lai KC, Huang AC, Chung JG.

Anticancer Res. 2018 Jul;38(7):3989-3997. doi: 10.21873/anticanres.12686.


Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-κB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways.

Juan TK, Liu KC, Kuo CL, Yang MD, Chu YL, Yang JL, Wu PP, Huang YP, Lai KC, Chung JG.

Oncol Lett. 2018 May;15(5):7716-7724. doi: 10.3892/ol.2018.8286. Epub 2018 Mar 16.


Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro.

Lai KC, Hsiao YT, Yang JL, Ma YS, Huang YP, Chiang TA, Chung JG.

Int J Oncol. 2017 Sep;51(3):832-840. doi: 10.3892/ijo.2017.4084. Epub 2017 Jul 27.


Cantharidin alters the expression of genes associated with the NKG2D-associated immune response in TSGH-8301 human bladder carcinoma cells.

Kuo JH, Huang AC, Lin JJ, Lai KC, Wu RS, Yang JL, Ji BC, Yang MD, Chu YL, Chung JG.

Oncol Lett. 2017 Jul;14(1):234-240. doi: 10.3892/ol.2017.6168. Epub 2017 May 12.


Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells.

Liu KC, Shih TY, Kuo CL, Ma YS, Yang JL, Wu PP, Huang YP, Lai KC, Chung JG.

Am J Chin Med. 2016;44(6):1289-1310. Epub 2016 Sep 15.


Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-[Formula: see text]B and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a Mouse Model In Vivo.

Shiue YW, Lu CC, Hsiao YP, Liao CL, Lin JP, Lai KC, Yu CC, Huang YP, Ho HC, Chung JG.

Am J Chin Med. 2016;44(3):637-61. doi: 10.1142/S0192415X1650035X. Epub 2016 Apr 24.


Tetrandrine induces programmed cell death in human oral cancer CAL 27 cells through the reactive oxygen species production and caspase-dependent pathways and associated with beclin-1-induced cell autophagy.

Lien JC, Lin MW, Chang SJ, Lai KC, Huang AC, Yu FS, Chung JG.

Environ Toxicol. 2017 Jan;32(1):329-343. doi: 10.1002/tox.22238. Epub 2016 Jan 29.


Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: Roles of apoptotic cell death and H460 tumor xenografts model.

Hsu YC, Chiang JH, Yu CS, Hsia TC, Wu RS, Lien JC, Lai KC, Yu FS, Chung JG.

Environ Toxicol. 2017 Jan;32(1):84-98. doi: 10.1002/tox.22214. Epub 2015 Nov 23.


Bisdemethoxycurcumin induces DNA damage and inhibits DNA repair associated protein expressions in NCI-H460 human lung cancer cells.

Yu CC, Yang ST, Huang WW, Peng SF, Huang AC, Tang NY, Liu HC, Yang MD, Lai KC, Chung JG.

Environ Toxicol. 2016 Dec;31(12):1859-1868. doi: 10.1002/tox.22187. Epub 2015 Aug 30.


Gallic acid induces DNA damage and inhibits DNA repair-associated protein expression in human oral cancer SCC-4 cells.

Weng SW, Hsu SC, Liu HC, Ji BC, Lien JC, Yu FS, Liu KC, Lai KC, Lin JP, Chung JG.

Anticancer Res. 2015 Apr;35(4):2077-84.


Suppression of the TNF-alpha level is mediated by Gan-Lu-Yin (traditional Chinese medicine) in human oral cancer cells through the NF-kappa B, AKT, and ERK-dependent pathways.

Yang JS, Wu CC, Lee HZ, Hsieh WT, Tang FY, Bau DT, Lai KC, Lien JC, Chung JG.

Environ Toxicol. 2016 Oct;31(10):1196-205. doi: 10.1002/tox.22127. Epub 2015 Feb 26.


Cantharidin induces DNA damage and inhibits DNA repair-associated protein expressions in TSGH8301 human bladder cancer cell.

Kuo JH, Shih TY, Lin JP, Lai KC, Lin ML, Yang MD, Chung JG.

Anticancer Res. 2015 Feb;35(2):795-804.


Applicability of adipose-derived stem cells in type 1 diabetes mellitus.

Lin HP, Chan TM, Fu RH, Chuu CP, Chiu SC, Tseng YH, Liu SP, Lai KC, Shih MC, Lin ZS, Chen HS, Yeh DC, Lin SZ.

Cell Transplant. 2015;24(3):521-32. doi: 10.3727/096368915X686977. Epub 2015 Jan 23. Review.


Diallyl trisulfide inhibits migration, invasion and angiogenesis of human colon cancer HT-29 cells and umbilical vein endothelial cells, and suppresses murine xenograft tumour growth.

Lai KC, Hsu SC, Yang JS, Yu CC, Lein JC, Chung JG.

J Cell Mol Med. 2015 Feb;19(2):474-84. doi: 10.1111/jcmm.12486. Epub 2014 Nov 17.

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