Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 92


Stable, Reactive and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonitriles.

Tu J, Svatunek D, Parvez S, Liu AC, Levandowski BJ, Eckvahl HJ, Peterson RT, Houk KN, Franzini RM.

Angew Chem Int Ed Engl. 2019 May 6. doi: 10.1002/anie.201903877. [Epub ahead of print]


Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.

Zhang B, Wang KB, Wang W, Wang X, Liu F, Zhu J, Shi J, Li LY, Han H, Xu K, Qiao HY, Zhang X, Jiao RH, Houk KN, Liang Y, Tan RX, Ge HM.

Nature. 2019 Apr;568(7750):122-126. doi: 10.1038/s41586-019-1021-x. Epub 2019 Mar 13.


Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes.

Yamano MM, Knapp RR, Ngamnithiporn A, Ramirez M, Houk KN, Stoltz BM, Garg NK.

Angew Chem Int Ed Engl. 2019 Apr 16;58(17):5653-5657. doi: 10.1002/anie.201900503. Epub 2019 Mar 20.


Structural Distortion of Cycloalkynes Influences Cycloaddition Rates both by Strain and Interaction Energies.

Hamlin TA, Levandowski BJ, Narsaria AK, Houk KN, Bickelhaupt FM.

Chemistry. 2019 May 2;25(25):6342-6348. doi: 10.1002/chem.201900295. Epub 2019 Mar 27.


Computational Protocol to Understand P450 Mechanisms and Design of Efficient and Selective Biocatalysts.

Caddell Haatveit K, Garcia-Borràs M, Houk KN.

Front Chem. 2019 Jan 11;6:663. doi: 10.3389/fchem.2018.00663. eCollection 2018. Review.


Mild Ring-Opening 1,3-Hydroborations of Non-Activated Cyclopropanes.

Wang D, Xue XS, Houk KN, Shi Z.

Angew Chem Int Ed Engl. 2018 Dec 17;57(51):16861-16865. doi: 10.1002/anie.201811036. Epub 2018 Nov 21.


Asymmetric phosphoric acid-catalyzed four-component Ugi reaction.

Zhang J, Yu P, Li SY, Sun H, Xiang SH, Wang JJ, Houk KN, Tan B.

Science. 2018 Sep 14;361(6407). pii: eaas8707. doi: 10.1126/science.aas8707.


Enzymatic one-step ring contraction for quinolone biosynthesis.

Kishimoto S, Hara K, Hashimoto H, Hirayama Y, Champagne PA, Houk KN, Tang Y, Watanabe K.

Nat Commun. 2018 Jul 19;9(1):2826. doi: 10.1038/s41467-018-05221-5.


A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.

Mallinson SJB, Machovina MM, Silveira RL, Garcia-Borràs M, Gallup N, Johnson CW, Allen MD, Skaf MS, Crowley MF, Neidle EL, Houk KN, Beckham GT, DuBois JL, McGeehan JE.

Nat Commun. 2018 Jun 27;9(1):2487. doi: 10.1038/s41467-018-04878-2.


Intramolecular Diels-Alder Approaches to the Decalin Core of Verongidolide: The Origin of the exo-Selectivity, a DFT Analysis.

Maiga-Wandiam B, Corbu A, Massiot G, Sautel F, Yu P, Lin BW, Houk KN, Cossy J.

J Org Chem. 2018 Jun 1;83(11):5975-5985. doi: 10.1021/acs.joc.8b00566. Epub 2018 May 16.


Direct single-molecule dynamic detection of chemical reactions.

Guan J, Jia C, Li Y, Liu Z, Wang J, Yang Z, Gu C, Su D, Houk KN, Zhang D, Guo X.

Sci Adv. 2018 Feb 9;4(2):eaar2177. doi: 10.1126/sciadv.aar2177. eCollection 2018 Feb.


Influence of water and enzyme SpnF on the dynamics and energetics of the ambimodal [6+4]/[4+2] cycloaddition.

Yang Z, Yang S, Yu P, Li Y, Doubleday C, Park J, Patel A, Jeon BS, Russell WK, Liu HW, Russell DH, Houk KN.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E848-E855. doi: 10.1073/pnas.1719368115. Epub 2018 Jan 18.


A Four-Step Synthesis of Substituted 5,11-Dicyano-6,12-diaryltetracenes with Enhanced Stability and High Fluorescence Emission.

Kerisit N, Gawel P, Levandowski B, Yang YF, García-López V, Trapp N, Ruhlmann L, Boudon C, Houk KN, Diederich F.

Chemistry. 2018 Jan 2;24(1):159-168. doi: 10.1002/chem.201703903. Epub 2017 Nov 15.


Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.

Baril SA, Koenig AL, Krone MW, Albanese KI, He CQ, Lee GY, Houk KN, Waters ML, Brustad EM.

J Am Chem Soc. 2017 Dec 6;139(48):17253-17256. doi: 10.1021/jacs.7b09223. Epub 2017 Nov 20.


Synthesis of [18 F]Fluoroarenes by Nucleophilic Radiofluorination of N-Arylsydnones.

Narayanam MK, Ma G, Champagne PA, Houk KN, Murphy JM.

Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13006-13010. doi: 10.1002/anie.201707274. Epub 2017 Sep 7.


Molecular Dynamics Simulations of Selective Metabolite Transport across the Propanediol Bacterial Microcompartment Shell.

Park J, Chun S, Bobik TA, Houk KN, Yeates TO.

J Phys Chem B. 2017 Aug 31;121(34):8149-8154. doi: 10.1021/acs.jpcb.7b07232. Epub 2017 Aug 22.


Ionic and Neutral Mechanisms for C-H Bond Silylation of Aromatic Heterocycles Catalyzed by Potassium tert-Butoxide.

Banerjee S, Yang YF, Jenkins ID, Liang Y, Toutov AA, Liu WB, Schuman DP, Grubbs RH, Stoltz BM, Krenske EH, Houk KN, Zare RN.

J Am Chem Soc. 2017 May 24;139(20):6880-6887. doi: 10.1021/jacs.6b13032. Epub 2017 May 12.


Analyzing Reaction Rates with the Distortion/Interaction-Activation Strain Model.

Bickelhaupt FM, Houk KN.

Angew Chem Int Ed Engl. 2017 Aug 14;56(34):10070-10086. doi: 10.1002/anie.201701486. Epub 2017 Jul 17. Review.


Palladium-Catalyzed Suzuki-Miyaura Coupling of Aryl Esters.

Ben Halima T, Zhang W, Yalaoui I, Hong X, Yang YF, Houk KN, Newman SG.

J Am Chem Soc. 2017 Jan 25;139(3):1311-1318. doi: 10.1021/jacs.6b12329. Epub 2017 Jan 11.


Biocatalytic trifluoromethylation of unprotected phenols.

Simon RC, Busto E, Richter N, Resch V, Houk KN, Kroutil W.

Nat Commun. 2016 Nov 11;7:13323. doi: 10.1038/ncomms13323.

Supplemental Content

Loading ...
Support Center