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Items: 11


In vitro and in silico approaches to unveil the mechanisms underlying the cytotoxic effect of juncunol on human hepatocarcinoma cells.

Rodrigues MJ, Vizetto-Duarte C, Gangadhar KN, Zengin G, Mollica A, Varela J, Barreira L, Custódio L.

Pharmacol Rep. 2018 Oct;70(5):896-899. doi: 10.1016/j.pharep.2018.02.001. Epub 2018 Feb 2.


Juncaceae species as sources of innovative bioactive compounds for the food industry: In vitro antioxidant activity, neuroprotective properties and in silico studies.

Rodrigues MJ, Gangadhar KN, Zengin G, Mollica A, Varela J, Barreira L, Custódio L.

Food Chem Toxicol. 2017 Sep;107(Pt B):590-596. doi: 10.1016/j.fct.2017.04.006. Epub 2017 Apr 8.


Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata.

Bruno de Sousa C, Gangadhar KN, Morais TR, Conserva GA, Vizetto-Duarte C, Pereira H, Laurenti MD, Campino L, Levy D, Uemi M, Barreira L, Custódio L, Passero LF, Lago JH, Varela J.

Exp Parasitol. 2017 Mar;174:1-9. doi: 10.1016/j.exppara.2017.01.002. Epub 2017 Jan 24.


Urban wastewater treatment by Tetraselmis sp. CTP4 (Chlorophyta).

Schulze PSC, Carvalho CFM, Pereira H, Gangadhar KN, Schüler LM, Santos TF, Varela JCS, Barreira L.

Bioresour Technol. 2017 Jan;223:175-183. doi: 10.1016/j.biortech.2016.10.027. Epub 2016 Oct 14.


Isolation of a euryhaline microalgal strain, Tetraselmis sp. CTP4, as a robust feedstock for biodiesel production.

Pereira H, Gangadhar KN, Schulze PS, Santos T, de Sousa CB, Schueler LM, Custódio L, Malcata FX, Gouveia L, Varela JC, Barreira L.

Sci Rep. 2016 Oct 21;6:35663. doi: 10.1038/srep35663.


Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage.

Vizetto-Duarte C, Custódio L, Gangadhar KN, Lago JH, Dias C, Matos AM, Neng N, Nogueira JM, Barreira L, Albericio F, Rauter AP, Varela J.

Phytomedicine. 2016 May 15;23(5):550-7. doi: 10.1016/j.phymed.2016.02.008. Epub 2016 Feb 26.


Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds.

Vizetto-Duarte C, Custódio L, Acosta G, Lago JH, Morais TR, Bruno de Sousa C, Gangadhar KN, Rodrigues MJ, Pereira H, Lima RT, Vasconcelos MH, Barreira L, Rauter AP, Albericio F, Varela J.

PeerJ. 2016 Feb 16;4:e1704. doi: 10.7717/peerj.1704. eCollection 2016.


Synthesis and evaluation of sodium deoxycholate sulfate as a lipid drug carrier to enhance the solubility, stability and safety of an amphotericin B inhalation formulation.

Gangadhar KN, Adhikari K, Srichana T.

Int J Pharm. 2014 Aug 25;471(1-2):430-8. doi: 10.1016/j.ijpharm.2014.05.066. Epub 2014 Jun 4.


Maritime halophyte species from southern Portugal as sources of bioactive molecules.

Rodrigues MJ, Gangadhar KN, Vizetto-Duarte C, Wubshet SG, Nyberg NT, Barreira L, Varela J, Custódio L.

Mar Drugs. 2014 Apr 10;12(4):2228-44. doi: 10.3390/md12042228.


Phase behavior of rifampicin in cholesterol-based liquid crystals and polyethylene glycol.

Gangadhar KN, Changsan V, Buatong W, Srichana T.

Eur J Pharm Sci. 2012 Dec 18;47(5):804-12. doi: 10.1016/j.ejps.2012.09.011. Epub 2012 Sep 28.


A glycerol-based carbon catalyst for the preparation of biodiesel.

Devi BL, Gangadhar KN, Prasad PS, Jagannadh B, Prasad RB.

ChemSusChem. 2009 Jul 20;2(7):617-20. doi: 10.1002/cssc.200900097. Epub 2009 May 22. No abstract available.


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