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Items: 1 to 20 of 32

1.

A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.

Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, Yoon E, Lombard DB, Bild A, Mehta G, Romero I, Chiang CY, Landen C, Cravatt B, Hurley TD, Larsen SD, Buckanovich RJ.

Cell Rep. 2019 Mar 12;26(11):3061-3075.e6. doi: 10.1016/j.celrep.2019.02.032.

2.

RAD51D splice variants and cancer-associated mutations reveal XRCC2 interaction to be critical for homologous recombination.

Baldock RA, Pressimone CA, Baird JM, Khodakov A, Luong TT, Grundy MK, Smith CM, Karpenshif Y, Bratton-Palmer DS, Prakash R, Jasin M, Garcin EB, Gon S, Modesti M, Bernstein KA.

DNA Repair (Amst). 2019 Apr;76:99-107. doi: 10.1016/j.dnarep.2019.02.008. Epub 2019 Feb 23.

PMID:
30836272
3.

RAD-ical New Insights into RAD51 Regulation.

Sullivan MR, Bernstein KA.

Genes (Basel). 2018 Dec 13;9(12). pii: E629. doi: 10.3390/genes9120629. Review.

4.

The global role for Cdc13 and Yku70 in preventing telomere resection across the genome.

Westmoreland JW, Mihalevic MJ, Bernstein KA, Resnick MA.

DNA Repair (Amst). 2018 Feb;62:8-17. doi: 10.1016/j.dnarep.2017.11.010. Epub 2017 Nov 29.

5.

Pib2 and the EGO complex are both required for activation of TORC1.

Varlakhanova NV, Mihalevic MJ, Bernstein KA, Ford MGJ.

J Cell Sci. 2017 Nov 15;130(22):3878-3890. doi: 10.1242/jcs.207910. Epub 2017 Oct 9.

6.

Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE.

Zacchi LF, Dittmar JC, Mihalevic MJ, Shewan AM, Schulz BL, Brodsky JL, Bernstein KA.

Dis Model Mech. 2017 Sep 1;10(9):1129-1140. doi: 10.1242/dmm.029926. Epub 2017 Aug 2.

7.

Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Kondrashova O, Nguyen M, Shield-Artin K, Tinker AV, Teng NNH, Harrell MI, Kuiper MJ, Ho GY, Barker H, Jasin M, Prakash R, Kass EM, Sullivan MR, Brunette GJ, Bernstein KA, Coleman RL, Floquet A, Friedlander M, Kichenadasse G, O'Malley DM, Oza A, Sun J, Robillard L, Maloney L, Bowtell D, Giordano H, Wakefield MJ, Kaufmann SH, Simmons AD, Harding TC, Raponi M, McNeish IA, Swisher EM, Lin KK, Scott CL; AOCS Study Group.

Cancer Discov. 2017 Sep;7(9):984-998. doi: 10.1158/2159-8290.CD-17-0419. Epub 2017 Jun 6.

8.

Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition Process.

Kong M, Liu L, Chen X, Driscoll KI, Mao P, Böhm S, Kad NM, Watkins SC, Bernstein KA, Wyrick JJ, Min JH, Van Houten B.

Mol Cell. 2016 Oct 20;64(2):376-387. doi: 10.1016/j.molcel.2016.09.005. Epub 2016 Oct 6.

9.

The Shu complex is a conserved regulator of homologous recombination.

Martino J, Bernstein KA.

FEMS Yeast Res. 2016 Sep;16(6). pii: fow073. Epub 2016 Sep 1.

10.

The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.

Godin SK, Zhang Z, Herken BW, Westmoreland JW, Lee AG, Mihalevic MJ, Yu Z, Sobol RW, Resnick MA, Bernstein KA.

Nucleic Acids Res. 2016 Sep 30;44(17):8199-215. doi: 10.1093/nar/gkw535. Epub 2016 Jun 13.

11.

Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication.

Godin SK, Sullivan MR, Bernstein KA.

Biochem Cell Biol. 2016 Oct;94(5):407-418. Epub 2016 Mar 31. Review.

12.

Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans.

McClendon TB, Sullivan MR, Bernstein KA, Yanowitz JL.

Genetics. 2016 May;203(1):133-45. doi: 10.1534/genetics.115.185827. Epub 2016 Mar 2.

13.

Tryptophan biosynthesis is important for resistance to replicative stress in Saccharomyces cerevisiae.

Godin SK, Lee AG, Baird JM, Herken BW, Bernstein KA.

Yeast. 2016 May;33(5):183-9. doi: 10.1002/yea.3150. Epub 2016 Mar 21.

14.

The Budding Yeast Ubiquitin Protease Ubp7 Is a Novel Component Involved in S Phase Progression.

Böhm S, Szakal B, Herken BW, Sullivan MR, Mihalevic MJ, Kabbinavar FF, Branzei D, Clark NL, Bernstein KA.

J Biol Chem. 2016 Feb 26;291(9):4442-52. doi: 10.1074/jbc.M115.671057. Epub 2016 Jan 6.

15.

Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52.

Gaines WA, Godin SK, Kabbinavar FF, Rao T, VanDemark AP, Sung P, Bernstein KA.

Nat Commun. 2015 Jul 28;6:7834. doi: 10.1038/ncomms8834.

16.

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination.

Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3495-504. doi: 10.1073/pnas.1507105112. Epub 2015 Jun 22.

17.

Evolutionary and functional analysis of the invariant SWIM domain in the conserved Shu2/SWS1 protein family from Saccharomyces cerevisiae to Homo sapiens.

Godin SK, Meslin C, Kabbinavar F, Bratton-Palmer DS, Hornack C, Mihalevic MJ, Yoshida K, Sullivan M, Clark NL, Bernstein KA.

Genetics. 2015 Apr;199(4):1023-33. doi: 10.1534/genetics.114.173518. Epub 2015 Feb 5.

18.

Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme.

Fu Q, Chow J, Bernstein KA, Makharashvili N, Arora S, Lee CF, Person MD, Rothstein R, Paull TT.

Mol Cell Biol. 2014 Mar;34(5):778-93. doi: 10.1128/MCB.00963-13. Epub 2013 Dec 16. Erratum in: Mol Cell Biol. 2014 Nov 15;34(22):4213.

19.

Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.

Bernstein KA, Mimitou EP, Mihalevic MJ, Chen H, Sunjaveric I, Symington LS, Rothstein R.

Genetics. 2013 Dec;195(4):1241-51. doi: 10.1534/genetics.113.157370. Epub 2013 Oct 4.

20.

The Shu complex regulates Rad52 localization during rDNA repair.

Bernstein KA, Juanchich A, Sunjevaric I, Rothstein R.

DNA Repair (Amst). 2013 Sep;12(9):786-90. doi: 10.1016/j.dnarep.2013.05.003. Epub 2013 Jun 19.

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