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Items: 1 to 20 of 56

1.

Glucosylceramidase Maintains Influenza Infection By Regulating Endocytosis.

Drews K, Calgi MP, Harrison WC, Drews CM, Costa-Pinheiro P, Shaw JJP, Jobe KA, Nelson EA, Han JD, Fox T, White JM, Kester M.

J Virol. 2019 Mar 27. pii: JVI.00017-19. doi: 10.1128/JVI.00017-19. [Epub ahead of print]

2.

Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.

Dyall J, Nelson EA, DeWald LE, Guha R, Hart BJ, Zhou H, Postnikova E, Logue J, Vargas WM, Gross R, Michelotti J, Deiuliis N, Bennett RS, Crozier I, Holbrook MR, Morris PJ, Klumpp-Thomas C, McKnight C, Mierzwa T, Shinn P, Glass PJ, Johansen LM, Jahrling PB, Hensley LE, Olinger GG Jr, Thomas C, White JM.

J Infect Dis. 2018 Nov 22;218(suppl_5):S672-S678. doi: 10.1093/infdis/jiy304.

PMID:
29939303
3.

Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments.

Hulseberg CE, Fénéant L, Szymańska KM, White JM.

MBio. 2018 Jan 2;9(1). pii: e01818-17. doi: 10.1128/mBio.01818-17.

4.

Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity.

Lee J, Nyenhuis DA, Nelson EA, Cafiso DS, White JM, Tamm LK.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7987-E7996. doi: 10.1073/pnas.1708052114. Epub 2017 Sep 5.

5.

HIV virions sense plasma membrane heterogeneity for cell entry.

Yang ST, Kreutzberger AJB, Kiessling V, Ganser-Pornillos BK, White JM, Tamm LK.

Sci Adv. 2017 Jun 28;3(6):e1700338. doi: 10.1126/sciadv.1700338. eCollection 2017 Jun.

6.

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.

Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris PJ, Guha R, Klumpp-Thomas C, McKnight C, Chen YC, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG Jr, White JM.

PLoS Negl Trop Dis. 2017 Apr 12;11(4):e0005540. doi: 10.1371/journal.pntd.0005540. eCollection 2017 Apr.

7.

Clomiphene and Its Isomers Block Ebola Virus Particle Entry and Infection with Similar Potency: Potential Therapeutic Implications.

Nelson EA, Barnes AB, Wiehle RD, Fontenot GK, Hoenen T, White JM.

Viruses. 2016 Aug 2;8(8). pii: E206. doi: 10.3390/v8080206.

8.

Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion.

Coleman CM, Sisk JM, Mingo RM, Nelson EA, White JM, Frieman MB.

J Virol. 2016 Sep 12;90(19):8924-33. doi: 10.1128/JVI.01429-16. Print 2016 Oct 1.

9.

Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry.

Tran EE, Nelson EA, Bonagiri P, Simmons JA, Shoemaker CJ, Schmaljohn CS, Kobinger GP, Zeitlin L, Subramaniam S, White JM.

J Virol. 2016 Aug 12;90(17):7618-27. doi: 10.1128/JVI.00406-16. Print 2016 Sep 1.

10.

The Roles of Histidines and Charged Residues as Potential Triggers of a Conformational Change in the Fusion Loop of Ebola Virus Glycoprotein.

Lee J, Gregory SM, Nelson EA, White JM, Tamm LK.

PLoS One. 2016 Mar 29;11(3):e0152527. doi: 10.1371/journal.pone.0152527. eCollection 2016.

11.

Fusion of Enveloped Viruses in Endosomes.

White JM, Whittaker GR.

Traffic. 2016 Jun;17(6):593-614. doi: 10.1111/tra.12389. Epub 2016 Apr 7. Review.

12.

Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes.

Simmons JA, D'Souza RS, Ruas M, Galione A, Casanova JE, White JM.

J Virol. 2015 Oct 14;90(1):605-10. doi: 10.1128/JVI.01828-15. Print 2016 Jan 1.

13.

A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.

Johansen LM, DeWald LE, Shoemaker CJ, Hoffstrom BG, Lear-Rooney CM, Stossel A, Nelson E, Delos SE, Simmons JA, Grenier JM, Pierce LT, Pajouhesh H, Lehár J, Hensley LE, Glass PJ, White JM, Olinger GG.

Sci Transl Med. 2015 Jun 3;7(290):290ra89. doi: 10.1126/scitranslmed.aaa5597.

PMID:
26041706
14.

HIV gp41-mediated membrane fusion occurs at edges of cholesterol-rich lipid domains.

Yang ST, Kiessling V, Simmons JA, White JM, Tamm LK.

Nat Chem Biol. 2015 Jun;11(6):424-31. doi: 10.1038/nchembio.1800. Epub 2015 Apr 27.

15.

Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step.

Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D'Souza RS, Casanova JE, White JM.

J Virol. 2015 Mar;89(5):2931-43. doi: 10.1128/JVI.03398-14. Epub 2014 Dec 31.

16.

Spatial localization of the Ebola virus glycoprotein mucin-like domain determined by cryo-electron tomography.

Tran EE, Simmons JA, Bartesaghi A, Shoemaker CJ, Nelson E, White JM, Subramaniam S.

J Virol. 2014 Sep;88(18):10958-62. doi: 10.1128/JVI.00870-14. Epub 2014 Jul 9.

17.

Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop.

Gregory SM, Larsson P, Nelson EA, Kasson PM, White JM, Tamm LK.

J Virol. 2014 Jun;88(12):6636-49. doi: 10.1128/JVI.00396-14. Epub 2014 Apr 2.

18.

FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.

Johansen LM, Brannan JM, Delos SE, Shoemaker CJ, Stossel A, Lear C, Hoffstrom BG, Dewald LE, Schornberg KL, Scully C, Lehár J, Hensley LE, White JM, Olinger GG.

Sci Transl Med. 2013 Jun 19;5(190):190ra79. doi: 10.1126/scitranslmed.3005471.

19.

Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infection.

Shoemaker CJ, Schornberg KL, Delos SE, Scully C, Pajouhesh H, Olinger GG, Johansen LM, White JM.

PLoS One. 2013;8(2):e56265. doi: 10.1371/journal.pone.0056265. Epub 2013 Feb 18. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/76780c06-ac81-48a3-8cce-509da6858fe5.

20.

Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography.

Cardone G, Brecher M, Fontana J, Winkler DC, Butan C, White JM, Steven AC.

J Virol. 2012 Nov;86(22):12129-37. doi: 10.1128/JVI.01880-12. Epub 2012 Aug 29.

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