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Items: 16

1.

Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.

Pascal KE, Dudgeon D, Trefry JC, Anantpadma M, Sakurai Y, Murin CD, Turner HL, Fairhurst J, Torres M, Rafique A, Yan Y, Badithe A, Yu K, Potocky T, Bixler SL, Chance TB, Pratt WD, Rossi FD, Shamblin JD, Wollen SE, Zelko JM, Carrion R Jr, Worwa G, Staples HM, Burakov D, Babb R, Chen G, Martin J, Huang TT, Erlandson K, Willis MS, Armstrong K, Dreier TM, Ward AB, Davey RA, Pitt MLM, Lipsich L, Mason P, Olson W, Stahl N, Kyratsous CA.

J Infect Dis. 2018 Nov 22;218(suppl_5):S612-S626. doi: 10.1093/infdis/jiy285.

2.

Virus-encoded miRNAs in Ebola virus disease.

Duy J, Honko AN, Altamura LA, Bixler SL, Wollen-Roberts S, Wauquier N, O'Hearn A, Mucker EM, Johnson JC, Shamblin JD, Zelko J, Botto MA, Bangura J, Coomber M, Pitt ML, Gonzalez JP, Schoepp RJ, Goff AJ, Minogue TD.

Sci Rep. 2018 Apr 24;8(1):6480. doi: 10.1038/s41598-018-23916-z.

3.

A conserved transcriptional response to intranasal Ebola virus exposure in nonhuman primates prior to onset of fever.

Speranza E, Bixler SL, Altamura LA, Arnold CE, Pratt WD, Taylor-Howell C, Burrows C, Aguilar W, Rossi F, Shamblin JD, Wollen SE, Zelko JM, Minogue T, Nagle E, Palacios G, Goff AJ, Connor JH.

Sci Transl Med. 2018 Mar 28;10(434). pii: eaaq1016. doi: 10.1126/scitranslmed.aaq1016.

PMID:
29593102
4.

Zika Virus Infection in Syrian Golden Hamsters and Strain 13 Guinea Pigs.

Miller LJ, Nasar F, Schellhase CW, Norris SL, Kimmel AE, Valdez SM, Wollen-Roberts SE, Shamblin JD, Sprague TR, Lugo-Roman LA, Jarman RG, Yoon IK, Alera MT, Bavari S, Pitt MLM, Haddow AD.

Am J Trop Med Hyg. 2018 Mar;98(3):864-867. doi: 10.4269/ajtmh.17-0686. Epub 2018 Feb 1.

5.

DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs.

Cashman KA, Wilkinson ER, Wollen SE, Shamblin JD, Zelko JM, Bearss JJ, Zeng X, Broderick KE, Schmaljohn CS.

Hum Vaccin Immunother. 2017 Dec 2;13(12):3010-3019. doi: 10.1080/21645515.2017.1382780. Epub 2017 Nov 14.

6.

A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever.

Cashman KA, Wilkinson ER, Shaia CI, Facemire PR, Bell TM, Bearss JJ, Shamblin JD, Wollen SE, Broderick KE, Sardesai NY, Schmaljohn CS.

Hum Vaccin Immunother. 2017 Dec 2;13(12):2902-2911. doi: 10.1080/21645515.2017.1356500. Epub 2017 Oct 18.

7.

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus.

Haddow AD, Nalca A, Rossi FD, Miller LJ, Wiley MR, Perez-Sautu U, Washington SC, Norris SL, Wollen-Roberts SE, Shamblin JD, Kimmel AE, Bloomfield HA, Valdez SM, Sprague TR, Principe LM, Bellanca SA, Cinkovich SS, Lugo-Roman L, Cazares LH, Pratt WD, Palacios GF, Bavari S, Pitt ML, Nasar F.

Emerg Infect Dis. 2017 Aug;23(8):1274-1281. doi: 10.3201/eid2308.170036. Epub 2017 Aug 15.

8.

Low potential for mechanical transmission of Ebola virus via house flies (Musca domestica).

Haddow AD, Nasar F, Schellhase CW, Moon RD, Padilla SL, Zeng X, Wollen-Roberts SE, Shamblin JD, Grimes EC, Zelko JM, Linthicum KJ, Bavari S, Pitt ML, Trefry JC.

Parasit Vectors. 2017 May 3;10(1):218. doi: 10.1186/s13071-017-2149-x.

9.

Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.

Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM.

Science. 2016 Mar 4;351(6277):1078-83. doi: 10.1126/science.aad5788. Epub 2016 Feb 18.

10.

Ebola Virus Infections in Nonhuman Primates Are Temporally Influenced by Glycoprotein Poly-U Editing Site Populations in the Exposure Material.

Trefry JC, Wollen SE, Nasar F, Shamblin JD, Kern SJ, Bearss JJ, Jefferson MA, Chance TB, Kugelman JR, Ladner JT, Honko AN, Kobs DJ, Wending MQ, Sabourin CL, Pratt WD, Palacios GF, Pitt ML.

Viruses. 2015 Dec 19;7(12):6739-54. doi: 10.3390/v7122969.

11.

Dose Response of MARV/Angola Infection in Cynomolgus Macaques following IM or Aerosol Exposure.

Johnston SC, Lin KL, Twenhafel NA, Raymond JL, Shamblin JD, Wollen SE, Wlazlowski CB, Wilkinson ER, Botto MA, Goff AJ.

PLoS One. 2015 Sep 28;10(9):e0138843. doi: 10.1371/journal.pone.0138843. eCollection 2015.

12.

Temporal Characterization of Marburg Virus Angola Infection following Aerosol Challenge in Rhesus Macaques.

Lin KL, Twenhafel NA, Connor JH, Cashman KA, Shamblin JD, Donnelly GC, Esham HL, Wlazlowski CB, Johnson JC, Honko AN, Botto MA, Yen J, Hensley LE, Goff AJ.

J Virol. 2015 Oct;89(19):9875-85. doi: 10.1128/JVI.01147-15. Epub 2015 Jul 22.

13.

Detailed analysis of the African green monkey model of Nipah virus disease.

Johnston SC, Briese T, Bell TM, Pratt WD, Shamblin JD, Esham HL, Donnelly GC, Johnson JC, Hensley LE, Lipkin WI, Honko AN.

PLoS One. 2015 Feb 23;10(2):e0117817. doi: 10.1371/journal.pone.0117817. eCollection 2015.

14.

Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox).

Mucker EM, Goff AJ, Shamblin JD, Grosenbach DW, Damon IK, Mehal JM, Holman RC, Carroll D, Gallardo N, Olson VA, Clemmons CJ, Hudson P, Hruby DE.

Antimicrob Agents Chemother. 2013 Dec;57(12):6246-53. doi: 10.1128/AAC.00977-13. Epub 2013 Oct 7.

15.

Lymphocyte death in a mouse model of Ebola virus infection.

Bradfute SB, Braun DR, Shamblin JD, Geisbert JB, Paragas J, Garrison A, Hensley LE, Geisbert TW.

J Infect Dis. 2007 Nov 15;196 Suppl 2:S296-304.

PMID:
17940964
16.

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox.

Earl PL, Americo JL, Wyatt LS, Eller LA, Whitbeck JC, Cohen GH, Eisenberg RJ, Hartmann CJ, Jackson DL, Kulesh DA, Martinez MJ, Miller DM, Mucker EM, Shamblin JD, Zwiers SH, Huggins JW, Jahrling PB, Moss B.

Nature. 2004 Mar 11;428(6979):182-5.

PMID:
15014500

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