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Items: 1 to 20 of 41


Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Mediterranean region based on mitochondrial sequences.

Bruno de Sousa C, Cox CJ, Brito L, Pavão MM, Pereira H, Ferreira A, Ginja C, Campino L, Bermejo R, Parente M, Varela J.

PLoS One. 2019 Jan 30;14(1):e0210143. doi: 10.1371/journal.pone.0210143. eCollection 2019.


In vitro and in silico approaches to unveil the mechanisms underlying the cytotoxic effect of juncunol on human hepatocarcinoma cells.

Rodrigues MJ, Vizetto-Duarte C, Gangadhar KN, Zengin G, Mollica A, Varela J, Barreira L, Custódio L.

Pharmacol Rep. 2018 Oct;70(5):896-899. doi: 10.1016/j.pharep.2018.02.001. Epub 2018 Feb 2.


Scale-up and large-scale production of Tetraselmis sp. CTP4 (Chlorophyta) for CO2 mitigation: from an agar plate to 100-m3 industrial photobioreactors.

Pereira H, Páramo J, Silva J, Marques A, Barros A, Maurício D, Santos T, Schulze P, Barros R, Gouveia L, Barreira L, Varela J.

Sci Rep. 2018 Mar 23;8(1):5112. doi: 10.1038/s41598-018-23340-3.


Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp. maritima: from traditional remedies to prospective products.

Pereira CG, Barreira L, Bijttebier S, Pieters L, Marques C, Santos TF, Rodrigues MJ, Varela J, Custódio L.

Sci Rep. 2018 Mar 16;8(1):4689. doi: 10.1038/s41598-018-23038-6.


Report of in vitro antileishmanial properties of Iberian macroalgae.

Bruno de Sousa C, Lago JHG, Macridachis J, Oliveira M, Brito L, Vizetto-Duarte C, Florindo C, Hendrickx S, Maes L, Morais T, Uemi M, Neto L, Dionísio L, Cortes S, Barreira L, Custódio L, Alberício F, Campino L, Varela J.

Nat Prod Res. 2018 Feb 9:1-5. doi: 10.1080/14786419.2018.1434637. [Epub ahead of print]


Fatty acid profiles of the main lipid classes of green seaweeds from fish pond aquaculture.

Cardoso C, Ripol A, Afonso C, Freire M, Varela J, Quental-Ferreira H, Pousão-Ferreira P, Bandarra N.

Food Sci Nutr. 2017 Aug 27;5(6):1186-1194. doi: 10.1002/fsn3.511. eCollection 2017 Nov.


Flashing LEDs for Microalgal Production.

Schulze PSC, Guerra R, Pereira H, Schüler LM, Varela JCS.

Trends Biotechnol. 2017 Nov;35(11):1088-1101. doi: 10.1016/j.tibtech.2017.07.011. Epub 2017 Aug 30. Review.


Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis).

Pereira CG, Barreira L, Bijttebier S, Pieters L, Neves V, Rodrigues MJ, Rivas R, Varela J, Custódio L.

J Pharm Biomed Anal. 2017 Oct 25;145:593-603. doi: 10.1016/j.jpba.2017.07.007. Epub 2017 Jul 18.


A first glance into the nutritional properties of the sea cucumber Parastichopus regalis from the Mediterranean Sea (SE Spain).

Roggatz CC, González-Wangüemert M, Pereira H, Vizetto-Duarte C, Rodrigues MJ, Barreira L, da Silva MM, Varela J, Custódio L.

Nat Prod Res. 2018 Jan;32(1):116-120. doi: 10.1080/14786419.2017.1331224. Epub 2017 May 19.


First report of the in vitro antileishmanial properties of extremophile plants from the Algarve Coast.

Oliveira M, João Rodrigues M, Pereira C, Neto RLDM, Junior PAS, Neng NDR, Nogueira JMF, Varela J, Barreira L, Custódio L.

Nat Prod Res. 2018 Mar;32(5):600-604. doi: 10.1080/14786419.2017.1326489. Epub 2017 May 11.


Searching for new sources of innovative products for the food industry within halophyte aromatic plants: In vitro antioxidant activity and phenolic and mineral contents of infusions and decoctions of Crithmum maritimum L.

Pereira CG, Barreira L, da Rosa Neng N, Nogueira JMF, Marques C, Santos TF, Varela J, Custódio L.

Food Chem Toxicol. 2017 Sep;107(Pt B):581-589. doi: 10.1016/j.fct.2017.04.018. Epub 2017 Apr 18.


Juncaceae species as sources of innovative bioactive compounds for the food industry: In vitro antioxidant activity, neuroprotective properties and in silico studies.

Rodrigues MJ, Gangadhar KN, Zengin G, Mollica A, Varela J, Barreira L, Custódio L.

Food Chem Toxicol. 2017 Sep;107(Pt B):590-596. doi: 10.1016/j.fct.2017.04.006. Epub 2017 Apr 8.


Unlocking the in vitro anti-inflammatory and antidiabetic potential of Polygonum maritimum.

Rodrigues MJ, Custódio L, Lopes A, Oliveira M, Neng NR, Nogueira JM, Martins A, Rauter AP, Varela J, Barreira L.

Pharm Biol. 2017 Dec;55(1):1348-1357. doi: 10.1080/13880209.2017.1301493.


Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata.

Bruno de Sousa C, Gangadhar KN, Morais TR, Conserva GA, Vizetto-Duarte C, Pereira H, Laurenti MD, Campino L, Levy D, Uemi M, Barreira L, Custódio L, Passero LF, Lago JH, Varela J.

Exp Parasitol. 2017 Mar;174:1-9. doi: 10.1016/j.exppara.2017.01.002. Epub 2017 Jan 24.


Urban wastewater treatment by Tetraselmis sp. CTP4 (Chlorophyta).

Schulze PSC, Carvalho CFM, Pereira H, Gangadhar KN, Schüler LM, Santos TF, Varela JCS, Barreira L.

Bioresour Technol. 2017 Jan;223:175-183. doi: 10.1016/j.biortech.2016.10.027. Epub 2016 Oct 14.


Isolation of a euryhaline microalgal strain, Tetraselmis sp. CTP4, as a robust feedstock for biodiesel production.

Pereira H, Gangadhar KN, Schulze PS, Santos T, de Sousa CB, Schueler LM, Custódio L, Malcata FX, Gouveia L, Varela JC, Barreira L.

Sci Rep. 2016 Oct 21;6:35663. doi: 10.1038/srep35663.


Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage.

Vizetto-Duarte C, Custódio L, Gangadhar KN, Lago JH, Dias C, Matos AM, Neng N, Nogueira JM, Barreira L, Albericio F, Rauter AP, Varela J.

Phytomedicine. 2016 May 15;23(5):550-7. doi: 10.1016/j.phymed.2016.02.008. Epub 2016 Feb 26.


Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds.

Vizetto-Duarte C, Custódio L, Acosta G, Lago JH, Morais TR, Bruno de Sousa C, Gangadhar KN, Rodrigues MJ, Pereira H, Lima RT, Vasconcelos MH, Barreira L, Rauter AP, Albericio F, Varela J.

PeerJ. 2016 Feb 16;4:e1704. doi: 10.7717/peerj.1704. eCollection 2016.


In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers' infusions and decoctions: A comparison with green tea (Camellia sinensis).

Rodrigues MJ, Neves V, Martins A, Rauter AP, Neng NR, Nogueira JM, Varela J, Barreira L, Custódio L.

Food Chem. 2016 Jun 1;200:322-9. doi: 10.1016/j.foodchem.2016.01.048. Epub 2016 Jan 13.


Methanol extracts from Cystoseira tamariscifolia and Cystoseira nodicaulis are able to inhibit cholinesterases and protect a human dopaminergic cell line from hydrogen peroxide-induced cytotoxicity.

Custódio L, Silvestre L, Rocha MI, Rodrigues MJ, Vizetto-Duarte C, Pereira H, Barreira L, Varela J.

Pharm Biol. 2016 Sep;54(9):1687-96. doi: 10.3109/13880209.2015.1123278. Epub 2016 Jan 5.


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