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Items: 20

1.

Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A 'Chemobrain' In Vitro Study.

Almeida D, Pinho R, Correia V, Soares J, Bastos ML, Carvalho F, Capela JP, Costa VM.

Pharmaceuticals (Basel). 2018 May 5;11(2). pii: E41. doi: 10.3390/ph11020041.

2.

Methylphenidate clinically oral doses improved brain and heart glutathione redox status and evoked renal and cardiac tissue injury in rats.

Loureiro-Vieira S, Costa VM, Duarte JA, Duarte-Araújo M, Gonçalves-Monteiro S, Maria de Lourdes B, Carvalho F, Capela JP.

Biomed Pharmacother. 2018 Apr;100:551-563. doi: 10.1016/j.biopha.2018.02.017. Epub 2018 Feb 23.

PMID:
29482048
3.

Methylphenidate effects in the young brain: friend or foe?

Loureiro-Vieira S, Costa VM, de Lourdes Bastos M, Carvalho F, Capela JP.

Int J Dev Neurosci. 2017 Aug;60:34-47. doi: 10.1016/j.ijdevneu.2017.04.002. Epub 2017 Apr 13. Review.

PMID:
28412445
4.

"Ecstasy" toxicity to adolescent rats following an acute low binge dose.

Teixeira-Gomes A, Costa VM, Feio-Azevedo R, Duarte JA, Duarte-Araújo M, Fernandes E, Bastos Mde L, Carvalho F, Capela JP.

BMC Pharmacol Toxicol. 2016 Jun 28;17(1):28. doi: 10.1186/s40360-016-0070-0.

5.

Mitochondria: key players in the neurotoxic effects of amphetamines.

Barbosa DJ, Capela JP, Feio-Azevedo R, Teixeira-Gomes A, Bastos Mde L, Carvalho F.

Arch Toxicol. 2015 Oct;89(10):1695-725. doi: 10.1007/s00204-015-1478-9. Epub 2015 Mar 6. Review.

PMID:
25743372
6.

The neurotoxicity of amphetamines during the adolescent period.

Teixeira-Gomes A, Costa VM, Feio-Azevedo R, Bastos Mde L, Carvalho F, Capela JP.

Int J Dev Neurosci. 2015 Apr;41:44-62. doi: 10.1016/j.ijdevneu.2014.12.001. Epub 2014 Dec 4. Review.

PMID:
25482046
7.

The mixture of "ecstasy" and its metabolites impairs mitochondrial fusion/fission equilibrium and trafficking in hippocampal neurons, at in vivo relevant concentrations.

Barbosa DJ, Serrat R, Mirra S, Quevedo M, de Barreda EG, Àvila J, Ferreira LM, Branco PS, Fernandes E, Lourdes Bastos Md, Capela JP, Soriano E, Carvalho F.

Toxicol Sci. 2014 Jun;139(2):407-20. doi: 10.1093/toxsci/kfu042. Epub 2014 Mar 4.

PMID:
24595818
8.

MDMA impairs mitochondrial neuronal trafficking in a Tau- and Mitofusin2/Drp1-dependent manner.

Barbosa DJ, Serrat R, Mirra S, Quevedo M, Gómez de Barreda E, Avila J, Fernandes E, Bastos Mde L, Capela JP, Carvalho F, Soriano E.

Arch Toxicol. 2014 Aug;88(8):1561-72. doi: 10.1007/s00204-014-1209-7. Epub 2014 Feb 13.

PMID:
24522274
9.

"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.

Barbosa DJ, Capela JP, Silva R, Ferreira LM, Branco PS, Fernandes E, Bastos ML, Carvalho F.

Arch Toxicol. 2014 Feb;88(2):515-31. doi: 10.1007/s00204-013-1147-9. Epub 2013 Nov 1.

PMID:
24177245
10.

The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.

Barbosa DJ, Capela JP, Silva R, Vilas-Boas V, Ferreira LM, Branco PS, Fernandes E, Bastos Mde L, Carvalho F.

Arch Toxicol. 2014 Feb;88(2):455-73. doi: 10.1007/s00204-013-1120-7. Epub 2013 Oct 8.

PMID:
24101030
11.

Differential Effects of Methyl-4-Phenylpyridinium Ion, Rotenone, and Paraquat on Differentiated SH-SY5Y Cells.

Martins JB, Bastos Mde L, Carvalho F, Capela JP.

J Toxicol. 2013;2013:347312. doi: 10.1155/2013/347312. Epub 2013 Mar 20.

12.

Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.

Ferreira PS, Nogueira TB, Costa VM, Branco PS, Ferreira LM, Fernandes E, Bastos ML, Meisel A, Carvalho F, Capela JP.

Toxicol Lett. 2013 Feb 4;216(2-3):159-70. doi: 10.1016/j.toxlet.2012.11.015. Epub 2012 Nov 27.

PMID:
23194825
13.

The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons.

Capela JP, da Costa Araújo S, Costa VM, Ruscher K, Fernandes E, Bastos Mde L, Dirnagl U, Meisel A, Carvalho F.

Neurotoxicology. 2013 Jan;34:254-63. doi: 10.1016/j.neuro.2012.09.005. Epub 2012 Sep 13.

PMID:
22983118
14.

Toxicity of amphetamines: an update.

Carvalho M, Carmo H, Costa VM, Capela JP, Pontes H, Remião F, Carvalho F, Bastos Mde L.

Arch Toxicol. 2012 Aug;86(8):1167-231. doi: 10.1007/s00204-012-0815-5. Epub 2012 Mar 6. Review.

PMID:
22392347
15.

Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes.

Barbosa DJ, Capela JP, Oliveira JM, Silva R, Ferreira LM, Siopa F, Branco PS, Fernandes E, Duarte JA, de Lourdes Bastos M, Carvalho F.

Br J Pharmacol. 2012 Feb;165(4b):1017-33. doi: 10.1111/j.1476-5381.2011.01453.x.

16.

Effect of 3,4-methylenedioxyamphetamine on dendritic spine dynamics in rat neocortical neurons--involvement of heat shock protein 27.

Ruscher K, Fernandes E, Capela JP, Bastos Mde L, Wieloch T, Dirnagl U, Meisel A, Carvalho F.

Brain Res. 2011 Jan 25;1370:43-52. doi: 10.1016/j.brainres.2010.11.022. Epub 2010 Nov 12.

PMID:
21075084
17.

Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview.

Capela JP, Carmo H, Remião F, Bastos ML, Meisel A, Carvalho F.

Mol Neurobiol. 2009 Jun;39(3):210-71. doi: 10.1007/s12035-009-8064-1. Epub 2009 Apr 17. Review.

PMID:
19373443
18.

5,7-Dihydroxitryptamine toxicity to serotonergic neurons in serum free raphe cultures.

Capela JP, Lautenschlager M, Dirnagl U, Bastos ML, Carvalho F, Meisel A.

Eur J Pharmacol. 2008 Jul 7;588(2-3):232-8. doi: 10.1016/j.ejphar.2008.04.046. Epub 2008 Apr 26.

PMID:
18519135
19.

Ecstasy induces apoptosis via 5-HT(2A)-receptor stimulation in cortical neurons.

Capela JP, Fernandes E, Remião F, Bastos ML, Meisel A, Carvalho F.

Neurotoxicology. 2007 Jul;28(4):868-75. Epub 2007 Apr 27.

PMID:
17572501
20.

Neurotoxicity of Ecstasy metabolites in rat cortical neurons, and influence of hyperthermia.

Capela JP, Meisel A, Abreu AR, Branco PS, Ferreira LM, Lobo AM, Remião F, Bastos ML, Carvalho F.

J Pharmacol Exp Ther. 2006 Jan;316(1):53-61. Epub 2005 Sep 23.

PMID:
16183702

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