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Items: 1 to 20 of 24


Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir.

Comer JE, Escaffre O, Neef N, Brasel T, Juelich TL, Smith JK, Smith J, Kalveram B, Perez DD, Massey S, Zhang L, Freiberg AN.

Viruses. 2019 Feb 3;11(2). pii: E137. doi: 10.3390/v11020137.


Zika virus infection elicits auto-antibodies to C1q.

Koma T, Veljkovic V, Anderson DE, Wang LF, Rossi SL, Shan C, Shi PY, Beasley DW, Bukreyeva N, Smith JN, Hallam S, Huang C, von Messling V, Paessler S.

Sci Rep. 2018 Jan 30;8(1):1882. doi: 10.1038/s41598-018-20185-8.


Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens.

Tong X, Smith J, Bukreyeva N, Koma T, Manning JT, Kalkeri R, Kwong AD, Paessler S.

Antiviral Res. 2018 Jan;149:34-40. doi: 10.1016/j.antiviral.2017.11.004. Epub 2017 Nov 8.


Mouse Model of Neurological Complications Resulting from Encephalitic Alphavirus Infection.

Ronca SE, Smith J, Koma T, Miller MM, Yun N, Dineley KT, Paessler S.

Front Microbiol. 2017 Feb 7;8:188. doi: 10.3389/fmicb.2017.00188. eCollection 2017.


The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor.

Koma T, Huang C, Aronson JF, Walker AG, Miller M, Smith JN, Patterson M, Paessler S.

PLoS Negl Trop Dis. 2016 Aug 31;10(8):e0004969. doi: 10.1371/journal.pntd.0004969. eCollection 2016 Aug.


Animal Model of Sensorineural Hearing Loss Associated with Lassa Virus Infection.

Yun NE, Ronca S, Tamura A, Koma T, Seregin AV, Dineley KT, Miller M, Cook R, Shimizu N, Walker AG, Smith JN, Fair JN, Wauquier N, Bockarie B, Khan SH, Makishima T, Paessler S.

J Virol. 2015 Dec 30;90(6):2920-7. doi: 10.1128/JVI.02948-15.


Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic.

Koma T, Patterson M, Huang C, Seregin AV, Maharaj PD, Miller M, Smith JN, Walker AG, Hallam S, Paessler S.

J Virol. 2015 Nov 18;90(3):1290-7. doi: 10.1128/JVI.02615-15. Print 2016 Feb 1.


The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.

Seregin AV, Yun NE, Miller M, Aronson J, Smith JK, Walker AG, Smith JN, Huang C, Manning JT, de la Torre JC, Paessler S.

J Virol. 2015 Jun;89(11):5949-56. doi: 10.1128/JVI.00104-15. Epub 2015 Mar 25.


A substitution in the transmembrane region of the glycoprotein leads to an unstable attenuation of Machupo virus.

Patterson M, Koma T, Seregin A, Huang C, Miller M, Smith J, Yun N, Smith J, Paessler S.

J Virol. 2014 Sep;88(18):10995-9. doi: 10.1128/JVI.01007-14. Epub 2014 Jul 16.


Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout mice.

Patterson M, Seregin A, Huang C, Kolokoltsova O, Smith J, Miller M, Smith J, Yun N, Poussard A, Grant A, Tigabu B, Walker A, Paessler S.

J Virol. 2014 Feb;88(4):1914-23. doi: 10.1128/JVI.02925-13. Epub 2013 Nov 27.


Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus.

Yun NE, Seregin AV, Walker DH, Popov VL, Walker AG, Smith JN, Miller M, de la Torre JC, Smith JK, Borisevich V, Fair JN, Wauquier N, Grant DS, Bockarie B, Bente D, Paessler S.

J Virol. 2013 Oct;87(19):10908-11. doi: 10.1128/JVI.01433-13. Epub 2013 Jul 31.


In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.

Poussard A, Patterson M, Taylor K, Seregin A, Smith J, Smith J, Salazar M, Paessler S.

J Vis Exp. 2012 Dec 2;(70):e4429. doi: 10.3791/4429.


Functional interferon system is required for clearance of lassa virus.

Yun NE, Poussard AL, Seregin AV, Walker AG, Smith JK, Aronson JF, Smith JN, Soong L, Paessler S.

J Virol. 2012 Mar;86(6):3389-92. doi: 10.1128/JVI.06284-11. Epub 2012 Jan 11.


Neuropathology of H5N1 virus infection in ferrets.

Peng BH, Yun N, Chumakova O, Zacks M, Campbell G, Smith J, Smith J, Linde S, Linde J, Paessler S.

Vet Microbiol. 2012 May 4;156(3-4):294-304. doi: 10.1016/j.vetmic.2011.11.025. Epub 2011 Dec 2.


Rapid, non-invasive imaging of alphaviral brain infection: reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals.

Patterson M, Poussard A, Taylor K, Seregin A, Smith J, Peng BH, Walker A, Linde J, Smith J, Salazar M, Paessler S.

Vaccine. 2011 Nov 21;29(50):9345-51. doi: 10.1016/j.vaccine.2011.09.130. Epub 2011 Oct 12.


Prevention of influenza virus shedding and protection from lethal H1N1 challenge using a consensus 2009 H1N1 HA and NA adenovirus vector vaccine.

Jones FR, Gabitzsch ES, Xu Y, Balint JP, Borisevich V, Smith J, Smith J, Peng BH, Walker A, Salazar M, Paessler S.

Vaccine. 2011 Sep 16;29(40):7020-6. doi: 10.1016/j.vaccine.2011.07.073. Epub 2011 Aug 5.


Mice lacking alpha/beta and gamma interferon receptors are susceptible to junin virus infection.

Kolokoltsova OA, Yun NE, Poussard AL, Smith JK, Smith JN, Salazar M, Walker A, Tseng CT, Aronson JF, Paessler S.

J Virol. 2010 Dec;84(24):13063-7. doi: 10.1128/JVI.01389-10. Epub 2010 Oct 6.


TC83 replicon vectored vaccine provides protection against Junin virus in guinea pigs.

Seregin AV, Yun NE, Poussard AL, Peng BH, Smith JK, Smith JN, Salazar M, Paessler S.

Vaccine. 2010 Jul 5;28(30):4713-8. doi: 10.1016/j.vaccine.2010.04.077. Epub 2010 May 7.


Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin.

Song L, Zhang Y, Yun NE, Poussard AL, Smith JN, Smith JK, Borisevich V, Linde JJ, Zacks MA, Li H, Kavita U, Reiserova L, Liu X, Dumuren K, Balasubramanian B, Weaver B, Parent J, Umlauf S, Liu G, Huleatt J, Tussey L, Paessler S.

Vaccine. 2009 Sep 25;27(42):5875-84. doi: 10.1016/j.vaccine.2009.07.060. Epub 2009 Aug 3.


CD4+ T cells provide protection against acute lethal encephalitis caused by Venezuelan equine encephalitis virus.

Yun NE, Peng BH, Bertke AS, Borisevich V, Smith JK, Smith JN, Poussard AL, Salazar M, Judy BM, Zacks MA, Estes DM, Paessler S.

Vaccine. 2009 Jun 19;27(30):4064-73. doi: 10.1016/j.vaccine.2009.04.015. Epub 2009 May 3.

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