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Items: 7

1.

State of the art of Smo antagonists for cancer therapy: advances in the target receptor and new ligand structures.

Espinosa-Bustos C, Mella J, Soto-Delgado J, Salas CO.

Future Med Chem. 2019 Mar;11(6):617-638. doi: 10.4155/fmc-2018-0497. Epub 2019 Mar 26.

PMID:
30912670
2.

Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs.

Suárez-Rozas C, Simpson S, Fuentes-Retamal S, Catalán M, Ferreira J, Theoduloz C, Mella J, Cabezas D, Cassels BK, Yáñez C, Castro-Castillo V.

Toxicol In Vitro. 2019 Feb;54:375-390. doi: 10.1016/j.tiv.2018.10.014. Epub 2018 Oct 30.

PMID:
30389605
3.

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections.

Campanini-Salinas J, Andrades-Lagos J, Gonzalez Rocha G, Choquesillo-Lazarte D, Bollo Dragnic S, Faúndez M, Alarcón P, Silva F, Vidal R, Salas-Huenuleo E, Kogan M, Mella J, Recabarren Gajardo G, Vásquez-Velásquez D.

Molecules. 2018 Jul 19;23(7). pii: E1776. doi: 10.3390/molecules23071776.

4.

Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles.

Lorca M, Morales-Verdejo C, Vásquez-Velásquez D, Andrades-Lagos J, Campanini-Salinas J, Soto-Delgado J, Recabarren-Gajardo G, Mella J.

Molecules. 2018 May 16;23(5). pii: E1191. doi: 10.3390/molecules23051191.

5.
6.

2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β₃-Adrenergic Activity.

Apablaza G, Montoya L, Morales-Verdejo C, Mellado M, Cuellar M, Lagos CF, Soto-Delgado J, Chung H, Pessoa-Mahana CD, Mella J.

Molecules. 2017 Mar 5;22(3). pii: E404. doi: 10.3390/molecules22030404.

7.

Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.

Romero-Parra J, Chung H, Tapia RA, Faúndez M, Morales-Verdejo C, Lorca M, Lagos CF, Di Marzo V, David Pessoa-Mahana C, Mella J.

Eur J Pharm Sci. 2017 Apr 1;101:1-10. doi: 10.1016/j.ejps.2017.01.037. Epub 2017 Jan 28.

PMID:
28137469

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