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Enhanced Intestinal Permeability and Plasma Concentration of Metformin in Rats by the Repeated Administration of Red Ginseng Extract.

Jin S, Lee S, Jeon JH, Kim H, Choi MK, Song IS.

Pharmaceutics. 2019 Apr 18;11(4). pii: E189. doi: 10.3390/pharmaceutics11040189.


HPLC-MS/MS analysis of ilimaquinone and its application in a pharmacokinetic study in rats.

Son H, Noh K, Kang C, Na M, Oh S, Song IS, Kang W.

J Pharm Biomed Anal. 2019 Mar 20;166:291-294. doi: 10.1016/j.jpba.2019.01.030. Epub 2019 Jan 17.


Ethanol extract of Glycyrrhizae Radix modulates the responses of antigen-specific splenocytes in experimental autoimmune encephalomyelitis.

Yang EJ, Song IS, Song KS.

Phytomedicine. 2019 Feb 15;54:56-65. doi: 10.1016/j.phymed.2018.09.189. Epub 2018 Sep 18.


Effects of Red Ginseng Extract on the Pharmacokinetics and Elimination of Methotrexate via Mrp2 Regulation.

Lee S, Kwon M, Choi MK, Song IS.

Molecules. 2018 Nov 12;23(11). pii: E2948. doi: 10.3390/molecules23112948.


Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug-Drug Interaction Potentials.

Rhee SJ, Lee HA, Lee S, Kim E, Jeon I, Song IS, Yu KS.

Pharm Res. 2018 Oct 15;35(12):236. doi: 10.1007/s11095-018-2511-5.


Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine.

Choi YA, Song IS, Choi MK.

Pharmaceutics. 2018 Aug 6;10(3). pii: E119. doi: 10.3390/pharmaceutics10030119.


A Comprehensive In Vivo and In Vitro Assessment of the Drug Interaction Potential of Red Ginseng.

Seong SJ, Kang WY, Heo JK, Jo J, Choi WG, Liu KH, Lee S, Choi MK, Han YH, Lee HS, Ohk B, Lee HW, Song IS, Yoon YR.

Clin Ther. 2018 Aug;40(8):1322-1337. doi: 10.1016/j.clinthera.2018.06.017. Epub 2018 Aug 2.


Effect of Red Ginseng Extract on the Pharmacokinetics and Efficacy of Metformin in Streptozotocin-Induced Diabetic Rats.

Nam SJ, Han YJ, Lee W, Kang B, Choi MK, Han YH, Song IS.

Pharmaceutics. 2018 Jul 3;10(3). pii: E80. doi: 10.3390/pharmaceutics10030080.


Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.

Lee JY, Han SH, Park MH, Baek B, Song IS, Choi MK, Takuwa Y, Ryu H, Kim SH, He X, Schuchman EH, Bae JS, Jin HK.

Nat Commun. 2018 Apr 16;9(1):1479. doi: 10.1038/s41467-018-03674-2.


Ursodeoxycholate Restores Biliary Excretion of Methotrexate in Rats with Ethinyl Estradiol Induced-Cholestasis by Restoring Canalicular Mrp2 Expression.

Kim MJ, Kang YJ, Kwon M, Choi YA, Choi MK, Chi HY, Yoo HH, Shim CK, Song IS.

Int J Mol Sci. 2018 Apr 9;19(4). pii: E1120. doi: 10.3390/ijms19041120.


Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats.

Choi MK, Lee J, Nam SJ, Kang YJ, Han Y, Choi K, Choi YA, Kwon M, Lee D, Song IS.

Mar Drugs. 2017 Sep 1;15(9). pii: E279. doi: 10.3390/md15090279.


Involvement of intestinal efflux and metabolic instability in the pharmacokinetics of platycodin D in rats.

Kwon M, Ji HK, Goo SH, Nam SJ, Kang YJ, Lee E, Liu KH, Choi MK, Song IS.

Drug Metab Pharmacokinet. 2017 Oct;32(5):248-254. doi: 10.1016/j.dmpk.2017.05.005. Epub 2017 Jun 8.


Comparative in vitro release and clinical pharmacokinetics of leuprolide from Luphere 3M Depot, a 3-month release formulation of leuprolide acetate.

Park S, Kim DH, Kim Y, Park JH, Lee M, Song IS, Shim CK.

Drug Dev Ind Pharm. 2017 Mar;43(3):441-447. doi: 10.1080/03639045.2016.1258409. Epub 2016 Nov 22.


Blockade of P-Glycoprotein Decreased the Disposition of Phenformin and Increased Plasma Lactate Level.

Choi MK, Song IS.

Biomol Ther (Seoul). 2016 Mar 1;24(2):199-205. doi: 10.4062/biomolther.2015.087.


Evidence supporting the need for considering the effects of smoking on drug disposition and effectiveness in medication practices: a systematic narrative review.

Sohn HS, Kim H, Song IS, Lim E, Kwon M, Ha JH, Kwon JW.

Int J Clin Pharmacol Ther. 2015 Aug;53(8):621-34. doi: 10.5414/CP202260. Review.


Enhanced oral bioavailability of morin administered in mixed micelle formulation with PluronicF127 and Tween80 in rats.

Choi YA, Yoon YH, Choi K, Kwon M, Goo SH, Cha JS, Choi MK, Lee HS, Song IS.

Biol Pharm Bull. 2015;38(2):208-17. doi: 10.1248/bpb.b14-00508.


Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide.

Jeong HU, Kwon M, Lee Y, Yoo JS, Shin DH, Song IS, Lee HS.

Drug Des Devel Ther. 2015 Jan 22;9:643-53. doi: 10.2147/DDDT.S75400. eCollection 2015.

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