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Items: 1 to 20 of 46

1.

A Pilot Study to Investigate the Balance between Proteases and α1-Antitrypsin in Bronchoalveolar Lavage Fluid of Lung Transplant Recipients.

Cagnone M, Piloni D, Ferrarotti I, Di Venere M, Viglio S, Magni S, Bardoni A, Salvini R, Fumagalli M, Iadarola P, Martinello S, Meloni F.

High Throughput. 2019 Feb 13;8(1). pii: E5. doi: 10.3390/ht8010005.

2.

The European Alpha-1 Research Collaboration (EARCO): a new ERS Clinical Research Collaboration to promote research in alpha-1 antitrypsin deficiency.

Miravitlles M, Chorostowska-Wynimko J, Ferrarotti I, McElvaney NG, O'Hara K, Stolk J, Stockley RA, Turner A, Wilkens M, Greulich T; EARCO Clinical Research Collaboration; Members of the EARCO Clinical Research Collaboration.

Eur Respir J. 2019 Feb 14;53(2). pii: 1900138. doi: 10.1183/13993003.00138-2019. Print 2019 Feb. No abstract available.

PMID:
30765486
3.

Author Correction: α1-Antitrypsin deficiency.

Greene CM, Marciniak SJ, Teckman J, Ferrarotti I, Brantly ML, Lomas DA, Stoller JK, McElvaney NG.

Nat Rev Dis Primers. 2018 Oct 29;4(1):40. doi: 10.1038/s41572-018-0043-2.

PMID:
30374103
4.

Update on α1-antitrypsin deficiency.

Ferrarotti I, Ottaviani S, De Silvestri A, Corsico AG.

Breathe (Sheff). 2018 Jun;14(2):e17-e24. doi: 10.1183/20734735.015018. Review.

5.

Real-world clinical applicability of pathogenicity predictors assessed on SERPINA1 mutations in alpha-1-antitrypsin deficiency.

Giacopuzzi E, Laffranchi M, Berardelli R, Ravasio V, Ferrarotti I, Gooptu B, Borsani G, Fra A.

Hum Mutat. 2018 Sep;39(9):1203-1213. doi: 10.1002/humu.23562. Epub 2018 Jun 28.

PMID:
29882371
6.

Alpha-1 antitrypsin deficiency: From the lung to the heart?

Curjuric I, Imboden M, Bettschart R, Caviezel S, Dratva J, Pons M, Rothe T, Schmidt-Trucksäss A, Stolz D, Thun GA, von Eckardstein A, Kronenberg F, Ferrarotti I, Probst-Hensch NM.

Atherosclerosis. 2018 Mar;270:166-172. doi: 10.1016/j.atherosclerosis.2018.01.042. Epub 2018 Jan 31.

PMID:
29432934
7.

Alpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications.

Chapman KR, Chorostowska-Wynimko J, Koczulla AR, Ferrarotti I, McElvaney NG.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 31;13:419-432. doi: 10.2147/COPD.S149429. eCollection 2018. Review.

8.

European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency.

Miravitlles M, Dirksen A, Ferrarotti I, Koblizek V, Lange P, Mahadeva R, McElvaney NG, Parr D, Piitulainen E, Roche N, Stolk J, Thabut G, Turner A, Vogelmeier C, Stockley RA.

Eur Respir J. 2017 Nov 30;50(5). pii: 1700610. doi: 10.1183/13993003.00610-2017. Print 2017 Nov. Review.

PMID:
29191952
9.

Case-finding for alpha1-antitrypsin deficiency in Kazakh patients with COPD.

Zhumagaliyeva A, Ottaviani S, Greulich T, Gorrini M, Vogelmeier C, Karazhanova L, Nurgazina G, DeSilvestri A, Kotke V, Barzon V, Zorzetto M, Corsico A, Ferrarotti I.

Multidiscip Respir Med. 2017 Oct 25;12:23. doi: 10.1186/s40248-017-0104-5. eCollection 2017.

10.

The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization.

Miranda E, Ferrarotti I, Berardelli R, Laffranchi M, Cerea M, Gangemi F, Haq I, Ottaviani S, Lomas DA, Irving JA, Fra A.

FEBS J. 2017 Jul;284(13):2110-2126. doi: 10.1111/febs.14111. Epub 2017 Jun 8.

11.

Advances in Identifying Urine/Serum Biomarkers in Alpha-1 Antitrypsin Deficiency for More Personalized Future Treatment Strategies.

Ferrarotti I, Corsico AG, Stolk J, Ottaviani S, Fumagalli M, Janciauskiene S, Iadarola P.

COPD. 2017 Feb;14(1):56-65. doi: 10.1080/15412555.2016.1241760. Epub 2016 Nov 9. Review.

PMID:
27827549
12.

α1-Antitrypsin deficiency.

Greene CM, Marciniak SJ, Teckman J, Ferrarotti I, Brantly ML, Lomas DA, Stoller JK, McElvaney NG.

Nat Rev Dis Primers. 2016 Jul 28;2:16051. doi: 10.1038/nrdp.2016.51. Review. Erratum in: Nat Rev Dis Primers. 2018 Oct 29;4(1):40.

PMID:
27465791
13.

Efficacy of augmentation therapy for emphysema associated with α1-antitrypsin deficiency: enough is enough.

Balbi B, Ferrarotti I, Miravitlles M.

Eur Respir J. 2016 Jan;47(1):35-8. doi: 10.1183/13993003.01145-2015. No abstract available.

14.

How Can We Improve the Detection of Alpha1-Antitrypsin Deficiency?

Ferrarotti I, Poplawska-Wisniewska B, Trevisan MT, Koepke J, Dresel M, Koczulla R, Ottaviani S, Baldo R, Gorrini M, Sala G, Cavallon L, Welte T, Chorostowska-Wynimko J, Luisetti M, Janciauskiene S.

PLoS One. 2015 Aug 13;10(8):e0135316. doi: 10.1371/journal.pone.0135316. eCollection 2015.

15.

Alternative transcripts of the SERPINA1 gene in alpha-1 antitrypsin deficiency.

Matamala N, Martínez MT, Lara B, Pérez L, Vázquez I, Jimenez A, Barquín M, Ferrarotti I, Blanco I, Janciauskiene S, Martinez-Delgado B.

J Transl Med. 2015 Jul 4;13:211. doi: 10.1186/s12967-015-0585-y.

16.

Italian registry of patients with alpha-1 antitrypsin deficiency: general data and quality of life evaluation.

Luisetti M, Ferrarotti I, Corda L, Ottaviani S, Gatta N, Tinelli C, Bruletti G, Bertella E, Balestroni G, Confalonieri M, Seebacher C, Iannacci L, Ferrari S, Salerno FG, Mariani F, Carone M, Balbi B.

COPD. 2015 May;12 Suppl 1:52-7. doi: 10.3109/15412555.2015.1023393.

PMID:
25938293
17.

Identification and characterisation of eight novel SERPINA1 Null mutations.

Ferrarotti I, Carroll TP, Ottaviani S, Fra AM, O'Brien G, Molloy K, Corda L, Medicina D, Curran DR, McElvaney NG, Luisetti M.

Orphanet J Rare Dis. 2014 Nov 26;9:172. doi: 10.1186/s13023-014-0172-y.

18.

Immune activation in α1-antitrypsin-deficiency emphysema. Beyond the protease-antiprotease paradigm.

Baraldo S, Turato G, Lunardi F, Bazzan E, Schiavon M, Ferrarotti I, Molena B, Cazzuffi R, Damin M, Balestro E, Luisetti M, Rea F, Calabrese F, Cosio MG, Saetta M.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):402-9. doi: 10.1164/rccm.201403-0529OC.

PMID:
25412116
19.

Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QOMadrid.

Lara B, Martínez MT, Blanco I, Hernández-Moro C, Velasco EA, Ferrarotti I, Rodriguez-Frias F, Perez L, Vazquez I, Alonso J, Posada M, Martínez-Delgado B.

Respir Res. 2014 Oct 7;15:125. doi: 10.1186/s12931-014-0125-y.

20.

The role of bronchial epithelial cells in the pathogenesis of COPD in Z-alpha-1 antitrypsin deficiency.

Pini L, Tiberio L, Venkatesan N, Bezzi M, Corda L, Luisetti M, Ferrarotti I, Malerba M, Lomas DA, Janciauskiene S, Vizzardi E, Modina D, Schiaffonati L, Tantucci C.

Respir Res. 2014 Sep 14;15:112. doi: 10.1186/s12931-014-0112-3.

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