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Items: 1 to 20 of 21

1.

A new mouse model for noninvasive fluorescence-based monitoring of mitochondrial UCP1 expression.

Kawarasaki S, Kuwata H, Sawazaki H, Sakamoto T, Nitta T, Kim CS, Jheng HF, Takahashi H, Nomura W, Ara T, Takahashi N, Tomita K, Yu R, Kawada T, Goto T.

FEBS Lett. 2019 May 10. doi: 10.1002/1873-3468.13430. [Epub ahead of print]

PMID:
31074834
2.

Soy hydrolysate enhances the isoproterenol-stimulated lipolytic pathway through an increase in β-adrenergic receptor expression in adipocytes.

Ng SP, Nomura W, Mohri S, Takahashi H, Jheng HF, Ara T, Nagai H, Ito T, Kawada T, Goto T.

Biosci Biotechnol Biochem. 2019 May 2:1-8. doi: 10.1080/09168451.2019.1611413. [Epub ahead of print]

PMID:
31045477
3.

Endoplasmic Reticulum Stress Impaired Uncoupling Protein 1 Expression via the Suppression of Peroxisome Proliferator-Activated Receptor γ Binding Activity in Mice Beige Adipocytes.

Yuliana A, Daijo A, Jheng HF, Kwon J, Nomura W, Takahashi H, Ara T, Kawada T, Goto T.

Int J Mol Sci. 2019 Jan 11;20(2). pii: E274. doi: 10.3390/ijms20020274.

4.

The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice.

Takeda K, Sawazaki H, Takahashi H, Yeh YS, Jheng HF, Nomura W, Ara T, Takahashi N, Seno S, Osato N, Matsuda H, Kawada T, Goto T.

FEBS Open Bio. 2018 Sep 19;8(11):1782-1793. doi: 10.1002/2211-5463.12498. eCollection 2018 Nov.

5.

The Mevalonate Pathway Is Indispensable for Adipocyte Survival.

Yeh YS, Jheng HF, Iwase M, Kim M, Mohri S, Kwon J, Kawarasaki S, Li Y, Takahashi H, Ara T, Nomura W, Kawada T, Goto T.

iScience. 2018 Nov 30;9:175-191. doi: 10.1016/j.isci.2018.10.019. Epub 2018 Oct 21.

6.

β-adrenergic Receptor Stimulation Revealed a Novel Regulatory Pathway via Suppressing Histone Deacetylase 3 to Induce Uncoupling Protein 1 Expression in Mice Beige Adipocyte.

Yuliana A, Jheng HF, Kawarasaki S, Nomura W, Takahashi H, Ara T, Kawada T, Goto T.

Int J Mol Sci. 2018 Aug 17;19(8). pii: E2436. doi: 10.3390/ijms19082436.

7.

A Phytol-Enriched Diet Activates PPAR-α in the Liver and Brown Adipose Tissue to Ameliorate Obesity-Induced Metabolic Abnormalities.

An JY, Jheng HF, Nagai H, Sanada K, Takahashi H, Iwase M, Watanabe N, Kim YI, Teraminami A, Takahashi N, Nakata R, Inoue H, Seno S, Mastuda H, Kawada T, Goto T.

Mol Nutr Food Res. 2018 Mar;62(6):e1700688. doi: 10.1002/mnfr.201700688. Epub 2018 Feb 22.

PMID:
29377597
8.

α-Linolenic acid-derived metabolites from gut lactic acid bacteria induce differentiation of anti-inflammatory M2 macrophages through G protein-coupled receptor 40.

Ohue-Kitano R, Yasuoka Y, Goto T, Kitamura N, Park SB, Kishino S, Kimura I, Kasubuchi M, Takahashi H, Li Y, Yeh YS, Jheng HF, Iwase M, Tanaka M, Masuda S, Inoue T, Yamakage H, Kusakabe T, Tani F, Shimatsu A, Takahashi N, Ogawa J, Satoh-Asahara N, Kawada T.

FASEB J. 2018 Jan;32(1):304-318. doi: 10.1096/fj.201700273R. Epub 2017 Sep 13.

PMID:
28904023
9.

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, enhances energy metabolism by activation of TRPV1.

Kim M, Furuzono T, Yamakuni K, Li Y, Kim YI, Takahashi H, Ohue-Kitano R, Jheng HF, Takahashi N, Kano Y, Yu R, Kishino S, Ogawa J, Uchida K, Yamazaki J, Tominaga M, Kawada T, Goto T.

FASEB J. 2017 Nov;31(11):5036-5048. doi: 10.1096/fj.201700151R. Epub 2017 Jul 28.

PMID:
28754711
10.

Suksdorfin Promotes Adipocyte Differentiation and Improves Abnormalities in Glucose Metabolism via PPARγ Activation.

Iwase M, Yamamoto T, Nishimura K, Takahashi H, Mohri S, Li Y, Jheng HF, Nomura W, Takahashi N, Kim CS, Yu R, Taniguchi M, Baba K, Murakami S, Kawada T, Goto T.

Lipids. 2017 Jul;52(7):657-664. doi: 10.1007/s11745-017-4269-7. Epub 2017 Jun 10.

PMID:
28601955
11.

Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytes.

Yang HE, Li Y, Nishimura A, Jheng HF, Yuliana A, Kitano-Ohue R, Nomura W, Takahashi N, Kim CS, Yu R, Kitamura N, Park SB, Kishino S, Ogawa J, Kawada T, Goto T.

Mol Nutr Food Res. 2017 Oct;61(10). doi: 10.1002/mnfr.201700064. Epub 2017 Jul 19.

PMID:
28544341
12.

The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice.

Goto T, Hirata M, Aoki Y, Iwase M, Takahashi H, Kim M, Li Y, Jheng HF, Nomura W, Takahashi N, Kim CS, Yu R, Seno S, Matsuda H, Aizawa-Abe M, Ebihara K, Itoh N, Kawada T.

J Biol Chem. 2017 Jun 2;292(22):9175-9190. doi: 10.1074/jbc.M116.767590. Epub 2017 Apr 12.

13.

Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses.

Li Y, Goto T, Ikutani R, Lin S, Takahashi N, Takahashi H, Jheng HF, Yu R, Taniguchi M, Baba K, Murakami S, Kawada T.

Obesity (Silver Spring). 2016 Nov;24(11):2351-2360. doi: 10.1002/oby.21611. Epub 2016 Sep 13.

14.

Dietary low-fat soy milk powder retards diabetic nephropathy progression via inhibition of renal fibrosis and renal inflammation.

Jheng HF, Hirotsuka M, Goto T, Shibata M, Matsumura Y, Kawada T.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600461. Epub 2016 Nov 29.

PMID:
27748993
15.

Geranylgeranyl pyrophosphate performs as an endogenous regulator of adipocyte function via suppressing the LXR pathway.

Yeh YS, Goto T, Takahashi N, Egawa K, Takahashi H, Jheng HF, Kim YI, Kawada T.

Biochem Biophys Res Commun. 2016 Sep 23;478(3):1317-22. doi: 10.1016/j.bbrc.2016.08.119. Epub 2016 Aug 26.

PMID:
27569282
16.

4-Hydroxyderricin, as a PPARγ Agonist, Promotes Adipogenesis, Adiponectin Secretion, and Glucose Uptake in 3T3-L1 Cells.

Li Y, Goto T, Yamakuni K, Takahashi H, Takahashi N, Jheng HF, Nomura W, Taniguchi M, Baba K, Murakami S, Kawada T.

Lipids. 2016 Jul;51(7):787-95. doi: 10.1007/s11745-016-4154-9. Epub 2016 Apr 20.

PMID:
27098252
17.

Egr-1 deficiency protects from renal inflammation and fibrosis.

Ho LC, Sung JM, Shen YT, Jheng HF, Chen SH, Tsai PJ, Tsai YS.

J Mol Med (Berl). 2016 Aug;94(8):933-42. doi: 10.1007/s00109-016-1403-6. Epub 2016 Mar 9.

PMID:
26960759
18.

Albumin stimulates renal tubular inflammation through an HSP70-TLR4 axis in mice with early diabetic nephropathy.

Jheng HF, Tsai PJ, Chuang YL, Shen YT, Tai TA, Chen WC, Chou CK, Ho LC, Tang MJ, Lai KT, Sung JM, Tsai YS.

Dis Model Mech. 2015 Oct 1;8(10):1311-21. doi: 10.1242/dmm.019398. Epub 2015 Aug 6.

19.

Molecular insight and pharmacological approaches targeting mitochondrial dynamics in skeletal muscle during obesity.

Jheng HF, Huang SH, Kuo HM, Hughes MW, Tsai YS.

Ann N Y Acad Sci. 2015 Sep;1350:82-94. doi: 10.1111/nyas.12863. Epub 2015 Aug 24. Review.

PMID:
26301786
20.

Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle.

Jheng HF, Tsai PJ, Guo SM, Kuo LH, Chang CS, Su IJ, Chang CR, Tsai YS.

Mol Cell Biol. 2012 Jan;32(2):309-19. doi: 10.1128/MCB.05603-11. Epub 2011 Nov 14.

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