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Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.

Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P.

Cancers (Basel). 2018 May 8;10(5). pii: E140. doi: 10.3390/cancers10050140.


Functional assessment of creatine transporter in control and X-linked SLC6A8-deficient fibroblasts.

Joncquel-Chevalier Curt M, Bout MA, Fontaine M, Kim I, Huet G, Bekri S, Morin G, Moortgat S, Moerman A, Cuisset JM, Cheillan D, Vamecq J.

Mol Genet Metab. 2018 Apr;123(4):463-471. doi: 10.1016/j.ymgme.2018.02.010. Epub 2018 Feb 16.


Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.

Gibault F, Bailly F, Corvaisier M, Coevoet M, Huet G, Melnyk P, Cotelle P.

ChemMedChem. 2017 Jun 21;12(12):954-961. doi: 10.1002/cmdc.201700063. Epub 2017 Apr 20.


Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse.

Corvaisier M, Bauzone M, Corfiotti F, Renaud F, El Amrani M, Monté D, Truant S, Leteurtre E, Formstecher P, Van Seuningen I, Gespach C, Huet G.

Oncotarget. 2016 Aug 30;7(35):56699-56712. doi: 10.18632/oncotarget.11057.


Non-Photoinduced Biological Properties of Verteporfin.

Gibault F, Corvaisier M, Bailly F, Huet G, Melnyk P, Cotelle P.

Curr Med Chem. 2016;23(11):1171-84. Review.


Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival.

Desurmont T, Skrypek N, Duhamel A, Jonckheere N, Millet G, Leteurtre E, Gosset P, Duchene B, Ramdane N, Hebbar M, Van Seuningen I, Pruvot FR, Huet G, Truant S.

Cancer Sci. 2015 Mar;106(3):262-9. doi: 10.1111/cas.12603. Epub 2015 Mar 5.


Tumour biology of colorectal liver metastasis is a more important factor in survival than surgical margin clearance in the era of modern chemotherapy regimens.

Truant S, Séquier C, Leteurtre E, Boleslawski E, Elamrani M, Huet G, Duhamel A, Hebbar M, Pruvot FR.

HPB (Oxford). 2015 Feb;17(2):176-84. doi: 10.1111/hpb.12316. Epub 2014 Jul 9. Review.


Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis.

Touil Y, Igoudjil W, Corvaisier M, Dessein AF, Vandomme J, Monté D, Stechly L, Skrypek N, Langlois C, Grard G, Millet G, Leteurtre E, Dumont P, Truant S, Pruvot FR, Hebbar M, Fan F, Ellis LM, Formstecher P, Van Seuningen I, Gespach C, Polakowska R, Huet G.

Clin Cancer Res. 2014 Feb 15;20(4):837-46. doi: 10.1158/1078-0432.CCR-13-1854. Epub 2013 Dec 9.


Volumetric analysis of remnant liver regeneration after major hepatectomy in bevacizumab-treated patients: a case-matched study in 82 patients.

Millet G, Truant S, Leteurtre E, Hebbar M, Zerbib P, Huet G, Boleslawski E, Pruvot FR.

Ann Surg. 2012 Nov;256(5):755-61; discussion 761-2. doi: 10.1097/SLA.0b013e31827381ca.


Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected].

Ledeen RW, Wu G, André S, Bleich D, Huet G, Kaltner H, Kopitz J, Gabius HJ.

Ann N Y Acad Sci. 2012 Apr;1253:206-21. doi: 10.1111/j.1749-6632.2012.06479.x. Review. Erratum in: Ann N Y Acad Sci. 2012 Jul;1258:191.


Pancreatic serous cystadenoma with compression of the main pancreatic duct: an unusual entity.

Truant S, Izgarevic D, Maunoury V, Buob D, Bulois P, Ernst O, Huet G, Zerbib P, Pruvot FR.

HPB Surg. 2011;2011:574378. doi: 10.1155/2011/574378. Epub 2011 Mar 14.


Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells.

Dessein AF, Stechly L, Jonckheere N, Dumont P, Monté D, Leteurtre E, Truant S, Pruvot FR, Figeac M, Hebbar M, Lecellier CH, Lesuffleur T, Dessein R, Grard G, Dejonghe MJ, de Launoit Y, Furuichi Y, Prévost G, Porchet N, Gespach C, Huet G.

Cancer Res. 2010 Jun 1;70(11):4644-54. doi: 10.1158/0008-5472.CAN-09-3828. Epub 2010 May 11.


REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells.

Rafa L, Dessein AF, Devisme L, Buob D, Truant S, Porchet N, Huet G, Buisine MP, Lesuffleur T.

Int J Oncol. 2010 Mar;36(3):689-98.


Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking.

Morelle W, Stechly L, André S, Van Seuningen I, Porchet N, Gabius HJ, Michalski JC, Huet G.

Biol Chem. 2009 Jul;390(7):529-44. doi: 10.1515/BC.2009.075.


Galectin-4-regulated delivery of glycoproteins to the brush border membrane of enterocyte-like cells.

Stechly L, Morelle W, Dessein AF, André S, Grard G, Trinel D, Dejonghe MJ, Leteurtre E, Drobecq H, Trugnan G, Gabius HJ, Huet G.

Traffic. 2009 Apr;10(4):438-50. doi: 10.1111/j.1600-0854.2009.00882.x. Epub 2009 Jan 24.


E-cadherin and beta-catenin mRNA levels throughout colon cancer progression.

Truant SC, Gouyer VP, Leteurtre EA, Zerimech F, Huet GM, Pruvot FR.

J Surg Res. 2008 Dec;150(2):212-8. doi: 10.1016/j.jss.2007.12.800. Epub 2008 Feb 11.


Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells.

Delacour D, Gouyer V, Zanetta JP, Drobecq H, Leteurtre E, Grard G, Moreau-Hannedouche O, Maes E, Pons A, André S, Le Bivic A, Gabius HJ, Manninen A, Simons K, Huet G.

J Cell Biol. 2005 May 9;169(3):491-501.


GC/MS identification and quantification of constituents of bacterial lipids and glycoconjugates obtained after methanolysis as heptafluorobutyrate derivatives.

Bohin A, Bouchart F, Richet C, Kol O, Leroy Y, Timmerman P, Huet G, Bohin JP, Zanetta JP.

Anal Biochem. 2005 May 15;340(2):231-44.


Tissue inhibitor of metalloproteinase 1 is an independent predictor of prognosis in patients with nonsmall cell lung carcinoma who undergo resection with curative intent.

Gouyer V, Conti M, Devos P, Zerimech F, Copin MC, Créme E, Wurtz A, Porte H, Huet G.

Cancer. 2005 Apr 15;103(8):1676-84.


Butyrate regulation of glycosylation-related gene expression: evidence for galectin-1 upregulation in human intestinal epithelial goblet cells.

Gaudier E, Forestier L, Gouyer V, Huet G, Julien R, Hoebler C.

Biochem Biophys Res Commun. 2004 Dec 17;325(3):1044-51.


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