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Items: 1 to 20 of 47


SUMOylation in Glioblastoma: A Novel Therapeutic Target.

Fox BM, Janssen A, Estevez-Ordonez D, Gessler F, Vicario N, Chagoya G, Elsayed G, Sotoudeh H, Stetler W, Friedman GK, Bernstock JD.

Int J Mol Sci. 2019 Apr 15;20(8). pii: E1853. doi: 10.3390/ijms20081853. Review.


Roseamonas gilardii Bacteremia in a Patient With HbS╬▓0-thalassemia: Clinical Implications and Literature Review.

Schlappi C, Bernstock JD, Ricketts W, Nix GA, Poole C, Lebensburger J, Friedman GK.

J Pediatr Hematol Oncol. 2019 Apr 3. doi: 10.1097/MPH.0000000000001476. [Epub ahead of print]


Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice.

Bernstock JD, Vicario N, Li R, Nan L, Totsch SK, Schlappi C, Gessler F, Han X, Parenti R, Beierle EA, Whitley RJ, Aban I, Gillespie GY, Markert JM, Friedman GK.

Cancer Gene Ther. 2019 Mar 28. doi: 10.1038/s41417-019-0091-0. [Epub ahead of print]


SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke.

Bernstock JD, Peruzzotti-Jametti L, Leonardi T, Vicario N, Ye D, Lee YJ, Maric D, Johnson KR, Mou Y, Van Den Bosch A, Winterbone M, Friedman GK, Franklin RJM, Hallenbeck JM, Pluchino S.

EBioMedicine. 2019 Apr;42:214-224. doi: 10.1016/j.ebiom.2019.03.035. Epub 2019 Mar 21.


Stereotactic Placement of Intratumoral Catheters for Continuous Infusion Delivery of Herpes Simplex Virus -1 G207 in Pediatric Malignant Supratentorial Brain Tumors.

Bernstock JD, Wright Z, Bag AK, Gessler F, Gillespie GY, Markert JM, Friedman GK, Johnston JM.

World Neurosurg. 2019 Feb;122:e1592-e1598. doi: 10.1016/j.wneu.2018.11.122. Epub 2018 Nov 24.


Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis.

Liu Z, Che P, Mercado JJ, Hackney JR, Friedman GK, Zhang C, You Z, Zhao X, Ding Q, Kim K, Li H, Liu X, Markert JM, Nabors B, Gillespie GY, Zhao R, Han X.

J Neurooncol. 2019 Jan;141(2):289-301. doi: 10.1007/s11060-018-03047-1. Epub 2018 Nov 20.


Quality Initiative to Improve time to Antibiotics for Febrile Pediatric Patients with Potential Neutropenia.

Monroe K, Cohen CT, Whelan K, King A, Maloney L, Deason J, Nichols JC, Friedman GK, Kutny M, Hayes L.

Pediatr Qual Saf. 2018 Aug 9;3(4):e095. doi: 10.1097/pq9.0000000000000095. eCollection 2018 Jul-Aug.


Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression.

Friedman GK, Bernstock JD, Chen D, Nan L, Moore BP, Kelly VM, Youngblood SL, Langford CP, Han X, Ring EK, Beierle EA, Gillespie GY, Markert JM.

Sci Rep. 2018 Sep 17;8(1):13930. doi: 10.1038/s41598-018-32353-x.


UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts.

Garner EF, Stafman LL, Williams AP, Aye JM, Goolsby C, Atigadda VR, Moore BP, Nan L, Stewart JE, Hjelmeland AB, Friedman GK, Beierle EA.

J Neurooncol. 2018 Nov;140(2):209-224. doi: 10.1007/s11060-018-2950-1. Epub 2018 Aug 21.


The Impact of Early Corticosteroid Pretreatment Before Initiation of Chemotherapy in Patients With Primary Central Nervous System Lymphoma.

Gessler F, Bernstock JD, Behmanesh B, Brunnberg U, Harter P, Ye D, Friedman GK, Hansmann ML, Wagner M, Seifert V, Weise L, Marquardt G.

Neurosurgery. 2018 Jul 17. doi: 10.1093/neuros/nyy272. [Epub ahead of print]


FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts.

Garner EF, Williams AP, Stafman LL, Aye JM, Mroczek-Musulman E, Moore BP, Stewart JE, Friedman GK, Beierle EA.

Sci Rep. 2018 May 2;8(1):6913. doi: 10.1038/s41598-018-25263-5.


Drugging SUMOylation for neuroprotection and oncotherapy.

Bernstock JD, Ye DG, Lee YJ, Gessler F, Friedman GK, Zheng W, Hallenbeck JM.

Neural Regen Res. 2018 Mar;13(3):415-416. doi: 10.4103/1673-5374.228718. No abstract available.


Cerebral Ischemia Increases Small Ubiquitin-Like Modifier Conjugation within Human Penumbral Tissue: Radiological-Pathological Correlation.

Bernstock JD, Ye DG, Griffin A, Lee YJ, Lynch J, Latour LL, Friedman GK, Maric D, Hallenbeck JM.

Front Neurol. 2018 Jan 12;8:738. doi: 10.3389/fneur.2017.00738. eCollection 2017.


Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002.

Ring EK, Li R, Moore BP, Nan L, Kelly VM, Han X, Beierle EA, Markert JM, Leavenworth JW, Gillespie GY, Friedman GK.

Mol Ther Oncolytics. 2017 Sep 13;7:27-36. doi: 10.1016/j.omto.2017.09.003. eCollection 2017 Dec 15.


Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.

Sorge C, Li R, Singh S, Reddy AT, Solomon DA, Perry A, Friedman GK.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26708. Epub 2017 Jul 11. Review.


Combination strategies enhance oncolytic virotherapy.

Friedman GK, Markert JM, Gillespie GY.

Oncotarget. 2017 May 23;8(21):34020-34021. doi: 10.18632/oncotarget.17643. No abstract available.


Rationale and Design of a Phase 1 Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain Tumors.

Waters AM, Johnston JM, Reddy AT, Fiveash J, Madan-Swain A, Kachurak K, Bag AK, Gillespie GY, Markert JM, Friedman GK.

Hum Gene Ther Clin Dev. 2017 Mar;28(1):7-16. doi: 10.1089/humc.2017.002.


Oncolytic Virotherapy for the Treatment of Malignant Glioma.

Foreman PM, Friedman GK, Cassady KA, Markert JM.

Neurotherapeutics. 2017 Apr;14(2):333-344. doi: 10.1007/s13311-017-0516-0. Review.


Rationale and Design of a Phase I Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain Tumors.

Waters AM, Johnston JM, Reddy AT, Fiveash J, Madan-Swain A, Kachurak K, Bag AK, Gillespie GY, Markert JM, Friedman GK.

Hum Gene Ther Clin Dev. 2017 Feb 24. doi: 10.1089/hum.2017.002. [Epub ahead of print]


Publication outcomes of abstracts from the American Society of Hematology Annual Meeting.

Baddam S, Cutter GR, Wolfson JA, Friedman GK, Lebensburger JD.

Am J Hematol. 2017 May;92(5):E81-E83. doi: 10.1002/ajh.24695. Epub 2017 Mar 20. No abstract available.

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