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Items: 1 to 20 of 46


Regorafenib Promotes Antitumor Immunity via Inhibiting PD-L1 and IDO1 Expression in Melanoma.

Wu RY, Kong PF, Xia LP, Huang Y, Li ZL, Tang YY, Chen YH, Li X, Senthilkumar R, Zhang HL, Sun T, Xu XL, Yu Y, Mai J, Peng XD, Yang D, Zhou LH, Feng GK, Deng R, Zhu XF.

Clin Cancer Res. 2019 Apr 2. doi: 10.1158/1078-0432.CCR-18-2840. [Epub ahead of print]


Exploration of Indole Alkaloids from Marine Fungus Pseudallescheria boydii F44-1 Using an Amino Acid-Directed Strategy.

Yuan MX, Qiu Y, Ran YQ, Feng GK, Deng R, Zhu XF, Lan WJ, Li HJ.

Mar Drugs. 2019 Jan 23;17(2). pii: E77. doi: 10.3390/md17020077.


XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells.

Ji J, Yu Y, Li ZL, Chen MY, Deng R, Huang X, Wang GF, Zhang MX, Yang Q, Ravichandran S, Feng GK, Xu XL, Yang CL, Qiu MZ, Jiao L, Yang D, Zhu XF.

Theranostics. 2018 Feb 5;8(6):1494-1510. doi: 10.7150/thno.21717. eCollection 2018.


CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation.

Li X, Wu XQ, Deng R, Li DD, Tang J, Chen WD, Chen JH, Ji J, Jiao L, Jiang S, Yang F, Feng GK, Senthilkumar R, Yue F, Zhang HL, Wu RY, Yu Y, Xu XL, Mai J, Li ZL, Peng XD, Huang Y, Huang X, Ma NF, Tao Q, Zeng YX, Zhu XF.

Nat Commun. 2017 Oct 27;8(1):1159. doi: 10.1038/s41467-017-01272-2.


Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2).

Jiao L, Zhang HL, Li DD, Yang KL, Tang J, Li X, Ji J, Yu Y, Wu RY, Ravichandran S, Liu JJ, Feng GK, Chen MS, Zeng YX, Deng R, Zhu XF.

Autophagy. 2018;14(4):671-684. doi: 10.1080/15548627.2017.1381804. Epub 2017 Dec 17.


Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells.

Lu QP, Chen WD, Peng JR, Xu YD, Cai Q, Feng GK, Ding K, Zhu XF, Guan Z.

Oncol Lett. 2016 Nov;12(5):3598-3608. Epub 2016 Sep 5.


Two New Pyripyropenes from the Marine Fungus Fusarium lateritium 2016F18-1.

Cao QX, Wei JH, Deng R, Feng GK, Zhu XF, Lan WJ, Li HJ.

Chem Biodivers. 2017 Mar;14(3). doi: 10.1002/cbdv.201600298. Epub 2017 Feb 27.


Additional New Cytotoxic Triquinane-Type Sesquiterpenoids Chondrosterins K-M from the Marine Fungus Chondrostereum sp.

Huang L, Lan WJ, Deng R, Feng GK, Xu QY, Hu ZY, Zhu XF, Li HJ.

Mar Drugs. 2016 Aug 26;14(9). pii: E157. doi: 10.3390/md14090157.


EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy.

Li YT, Qian XJ, Yu Y, Li ZH, Wu RY, Ji J, Jiao L, Li X, Kong PF, Chen WD, Feng GK, Deng R, Zhu XF.

Oncotarget. 2015 Jul 10;6(19):17491-500.


Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth.

Sun T, Li X, Zhang P, Chen WD, Zhang HL, Li DD, Deng R, Qian XJ, Jiao L, Ji J, Li YT, Wu RY, Yu Y, Feng GK, Zhu XF.

Nat Commun. 2015 May 26;6:7215. doi: 10.1038/ncomms8215.


Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors.

Qian XJ, Li YT, Yu Y, Yang F, Deng R, Ji J, Jiao L, Li X, Wu RY, Chen WD, Feng GK, Zhu XF.

Oncotarget. 2015 Mar 10;6(7):5134-46.


DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2.

Qin J, Ji J, Deng R, Tang J, Yang F, Feng GK, Chen WD, Wu XQ, Qian XJ, Ding K, Zhu XF.

Oncotarget. 2015 Mar 30;6(9):6944-58.


ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells.

Chen JH, Zhang P, Chen WD, Li DD, Wu XQ, Deng R, Jiao L, Li X, Ji J, Feng GK, Zeng YX, Jiang JW, Zhu XF.

Autophagy. 2015;11(2):239-52. doi: 10.1080/15548627.2015.1009767.


Cytotoxic prenylated xanthones from the pericarps of Garcinia mangostana.

Xu Z, Huang L, Chen XH, Zhu XF, Qian XJ, Feng GK, Lan WJ, Li HJ.

Molecules. 2014 Feb 6;19(2):1820-7. doi: 10.3390/molecules19021820.


A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling.

Qin J, Tang J, Jiao L, Ji J, Chen WD, Feng GK, Gao YH, Zhu XF, Deng R.

Life Sci. 2013 Nov 4;93(18-19):655-63. doi: 10.1016/j.lfs.2013.09.002. Epub 2013 Sep 14.


Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 has a therapeutic potential and sensitizes cisplatin in nasopharyngeal carcinoma.

Yang F, Qian XJ, Qin W, Deng R, Wu XQ, Qin J, Feng GK, Zhu XF.

PLoS One. 2013;8(3):e59879. doi: 10.1371/journal.pone.0059879. Epub 2013 Mar 22.


The inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatment.

Li DD, Sun T, Wu XQ, Chen SP, Deng R, Jiang S, Feng GK, Pan JX, Zhang XS, Zeng YX, Zhu XF.

PLoS One. 2012;7(9):e45058. Epub 2012 Sep 14.


Upregulation of sestrin 2 expression via JNK pathway activation contributes to autophagy induction in cancer cells.

Zhang XY, Wu XQ, Deng R, Sun T, Feng GK, Zhu XF.

Cell Signal. 2013 Jan;25(1):150-8. doi: 10.1016/j.cellsig.2012.09.004. Epub 2012 Sep 7.


Hirsutanol A induces apoptosis and autophagy via reactive oxygen species accumulation in breast cancer MCF-7 cells.

Yang F, Chen WD, Deng R, Li DD, Wu KW, Feng GK, Li HJ, Zhu XF.

J Pharmacol Sci. 2012;119(3):214-20. Epub 2012 Jun 13.

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