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Items: 1 to 20 of 126

1.

Prion Efficiently Replicates in α-Synuclein Knockout Mice.

Bistaffa E, Rossi M, De Luca CMG, Cazzaniga F, Carletta O, Campagnani I, Tagliavini F, Legname G, Giaccone G, Moda F.

Mol Neurobiol. 2019 Apr 30. doi: 10.1007/s12035-019-1602-6. [Epub ahead of print]

PMID:
31041657
2.

Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration.

Scialò C, De Cecco E, Manganotti P, Legname G.

Viruses. 2019 Mar 14;11(3). pii: E261. doi: 10.3390/v11030261. Review.

3.

Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure.

Ponzini E, De Palma A, Cerboni L, Natalello A, Rossi R, Moons R, Konijnenberg A, Narkiewicz J, Legname G, Sobott F, Mauri P, Santambrogio C, Grandori R.

J Biol Chem. 2019 Apr 5;294(14):5657-5665. doi: 10.1074/jbc.RA118.001907. Epub 2019 Feb 12.

4.

Copper Binding Regulates Cellular Prion Protein Function.

Nguyen XTA, Tran TH, Cojoc D, Legname G.

Mol Neurobiol. 2019 Feb 7. doi: 10.1007/s12035-019-1510-9. [Epub ahead of print]

PMID:
30729399
5.

Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases.

Meneghetti E, Gasperini L, Virgilio T, Moda F, Tagliavini F, Benetti F, Legname G.

Mol Neurobiol. 2019 Feb 1. doi: 10.1007/s12035-019-1505-6. [Epub ahead of print]

PMID:
30710214
6.

Brain aging: A Ianus-faced player between health and neurodegeneration.

Vanni S, Colini Baldeschi A, Zattoni M, Legname G.

J Neurosci Res. 2019 Jan 11. doi: 10.1002/jnr.24379. [Epub ahead of print] Review.

PMID:
30632202
7.

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene.

Di Fede G, Catania M, Atzori C, Moda F, Pasquali C, Indaco A, Grisoli M, Zuffi M, Guaita MC, Testi R, Taraglio S, Sessa M, Gusmaroli G, Spinelli M, Salzano G, Legname G, Tarletti R, Godi L, Pocchiari M, Tagliavini F, Imperiale D, Giaccone G.

Acta Neuropathol Commun. 2019 Jan 3;7(1):1. doi: 10.1186/s40478-018-0656-4.

8.

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.

Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML.

J Med Chem. 2018 Sep 13;61(17):7640-7656. doi: 10.1021/acs.jmedchem.8b00610. Epub 2018 Aug 24.

PMID:
30078314
9.

Synthetic Prion Selection and Adaptation.

Bistaffa E, Moda F, Virgilio T, Campagnani I, De Luca CMG, Rossi M, Salzano G, Giaccone G, Tagliavini F, Legname G.

Mol Neurobiol. 2019 Apr;56(4):2978-2989. doi: 10.1007/s12035-018-1279-2. Epub 2018 Aug 3.

PMID:
30074230
10.

Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases.

Legname G, Virgilio T, Bistaffa E, De Luca CMG, Catania M, Zago P, Isopi E, Campagnani I, Tagliavini F, Giaccone G, Moda F.

Prion. 2018 Mar 4;12(2):127-137. doi: 10.1080/19336896.2018.1464367. Epub 2018 May 18.

11.

Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles.

Vitali M, Rigamonti V, Natalello A, Colzani B, Avvakumova S, Brocca S, Santambrogio C, Narkiewicz J, Legname G, Colombo M, Prosperi D, Grandori R.

Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1556-1564. doi: 10.1016/j.bbagen.2018.03.026. Epub 2018 Apr 2.

PMID:
29621630
12.

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases.

Vanni S, Zattoni M, Moda F, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Carmona M, Ferrer I, Kovacs GG, Legname G.

Front Neurosci. 2018 Jan 22;12:8. doi: 10.3389/fnins.2018.00008. eCollection 2018.

13.

The role of the prion protein in the internalization of α-synuclein amyloids.

De Cecco E, Legname G.

Prion. 2018 Jan 2;12(1):23-27. doi: 10.1080/19336896.2017.1423186. Epub 2018 Jan 31.

14.

Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations.

Prada I, Gabrielli M, Turola E, Iorio A, D'Arrigo G, Parolisi R, De Luca M, Pacifici M, Bastoni M, Lombardi M, Legname G, Cojoc D, Buffo A, Furlan R, Peruzzi F, Verderio C.

Acta Neuropathol. 2018 Apr;135(4):529-550. doi: 10.1007/s00401-017-1803-x. Epub 2018 Jan 4.

15.

The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein.

Giachin G, Nepravishta R, Mandaliti W, Melino S, Margon A, Scaini D, Mazzei P, Piccolo A, Legname G, Paci M, Leita L.

PLoS One. 2017 Nov 21;12(11):e0188308. doi: 10.1371/journal.pone.0188308. eCollection 2017.

16.

Elucidating the function of the prion protein.

Legname G.

PLoS Pathog. 2017 Aug 31;13(8):e1006458. doi: 10.1371/journal.ppat.1006458. eCollection 2017 Aug. Review. No abstract available.

17.

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.

Aulić S, Masperone L, Narkiewicz J, Isopi E, Bistaffa E, Ambrosetti E, Pastore B, De Cecco E, Scaini D, Zago P, Moda F, Tagliavini F, Legname G.

Sci Rep. 2017 Aug 30;7(1):10050. doi: 10.1038/s41598-017-10236-x.

18.

Preface.

Legname G, Vanni S.

Prog Mol Biol Transl Sci. 2017;150:xvii-xix. doi: 10.1016/S1877-1173(17)30128-X. No abstract available.

PMID:
28838677
19.

The Prion Concept and Synthetic Prions.

Legname G, Moda F.

Prog Mol Biol Transl Sci. 2017;150:147-156. doi: 10.1016/bs.pmbts.2017.06.002. Epub 2017 Jul 20. Review.

PMID:
28838659
20.

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia.

Redaelli V, Bistaffa E, Zanusso G, Salzano G, Sacchetto L, Rossi M, De Luca CM, Di Bari M, Portaleone SM, Agrimi U, Legname G, Roiter I, Forloni G, Tagliavini F, Moda F.

Sci Rep. 2017 Apr 7;7:46269. doi: 10.1038/srep46269.

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