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Items: 1 to 20 of 116

1.

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, Seitz-Polsky B, Skhiri T, Van Obberghen-Schilling E, Van Obberghen E, Yvan-Charvet L.

Cancers (Basel). 2019 Feb 21;11(2). pii: E250. doi: 10.3390/cancers11020250.

2.

The Transcription Factor Function of Parkin: Breaking the Dogma.

Alves da Costa C, Duplan E, Rouland L, Checler F.

Front Neurosci. 2019 Jan 15;12:965. doi: 10.3389/fnins.2018.00965. eCollection 2018. Review.

3.

Chronic fornix deep brain stimulation in a transgenic Alzheimer's rat model reduces amyloid burden, inflammation, and neuronal loss.

Leplus A, Lauritzen I, Melon C, Kerkerian-Le Goff L, Fontaine D, Checler F.

Brain Struct Funct. 2019 Jan;224(1):363-372. doi: 10.1007/s00429-018-1779-x. Epub 2018 Oct 19.

PMID:
30341742
4.

Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking.

Paumier JM, Py NA, García-González L, Bernard A, Stephan D, Louis L, Checler F, Khrestchatisky M, Baranger K, Rivera S.

FASEB J. 2019 Feb;33(2):2910-2927. doi: 10.1096/fj.201801076R. Epub 2018 Oct 17.

PMID:
30332299
5.

Neurolysin: From Initial Detection to Latest Advances.

Checler F, Ferro ES.

Neurochem Res. 2018 Nov;43(11):2017-2024. doi: 10.1007/s11064-018-2624-6. Epub 2018 Aug 29. Review.

PMID:
30159819
6.

Are N- and C-terminally truncated Aβ species key pathological triggers in Alzheimer's disease?

Dunys J, Valverde A, Checler F.

J Biol Chem. 2018 Oct 5;293(40):15419-15428. doi: 10.1074/jbc.R118.003999. Epub 2018 Aug 24. Review.

PMID:
30143530
7.

Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice.

Bourgeois A, Lauritzen I, Lorivel T, Bauer C, Checler F, Pardossi-Piquard R.

Neurobiol Aging. 2018 Nov;71:21-31. doi: 10.1016/j.neurobiolaging.2018.06.038. Epub 2018 Jul 12.

PMID:
30071370
8.

Nuclear TP53: An unraveled function as transcriptional repressor of PINK1.

Checler F, Goiran T, Alves da Costa C.

Autophagy. 2018;14(6):1099-1101. doi: 10.1080/15548627.2018.1450022. Epub 2018 May 11.

9.

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation.

Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, You H, Checler F, Alves da Costa C.

Cell Death Differ. 2018 May;25(5):873-884. doi: 10.1038/s41418-017-0016-0. Epub 2018 Jan 19.

10.

Presenilins at the crossroad of a functional interplay between PARK2/PARKIN and PINK1 to control mitophagy: Implication for neurodegenerative diseases.

Checler F, Goiran T, Alves da Costa C.

Autophagy. 2017;13(11):2004-2005. doi: 10.1080/15548627.2017.1363950. Epub 2017 Sep 21.

11.

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.

Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR.

Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19.

PMID:
28631094
12.

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.

Goiran T, Duplan E, Chami M, Bourgeois A, El Manaa W, Rouland L, Dunys J, Lauritzen I, You H, Stambolic V, Biféri MG, Barkats M, Pimplikar SW, Sergeant N, Colin M, Morais VA, Pardossi-Piquard R, Checler F, Alves da Costa C.

Biol Psychiatry. 2018 Mar 1;83(5):416-427. doi: 10.1016/j.biopsych.2017.04.011. Epub 2017 May 3.

13.

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

Bussiere R, Lacampagne A, Reiken S, Liu X, Scheuerman V, Zalk R, Martin C, Checler F, Marks AR, Chami M.

J Biol Chem. 2017 Jun 16;292(24):10153-10168. doi: 10.1074/jbc.M116.743070. Epub 2017 May 5.

14.

MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro.

Baranger K, Bonnet AE, Girard SD, Paumier JM, García-González L, Elmanaa W, Bernard A, Charrat E, Stephan D, Bauer C, Moschke K, Lichtenthaler SF, Roman FS, Checler F, Khrestchatisky M, Rivera S.

Front Mol Neurosci. 2017 Jan 10;9:163. doi: 10.3389/fnmol.2016.00163. eCollection 2016.

15.

The Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities.

Htoo HH, Limsuvan S, Thamsermsang O, Hernandez JF, Checler F, Govitrapong P, Pakaprot N, Akarasereenont P, Vincent B.

PLoS One. 2017 Jan 20;12(1):e0170360. doi: 10.1371/journal.pone.0170360. eCollection 2017.

16.

The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease.

Cissé M, Duplan E, Checler F.

Mol Med. 2017 Feb;22:905-917. doi: 10.2119/molmed.2016.00229. Epub 2017 Jan 4.

17.

α-synuclein and p53 functional interplay in physiopathological contexts.

Alves da Costa C, Duplan E, Checler F.

Oncotarget. 2017 Feb 7;8(6):9001-9002. doi: 10.18632/oncotarget.14385. No abstract available.

18.

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.

Chapuis J, Flaig A, Grenier-Boley B, Eysert F, Pottiez V, Deloison G, Vandeputte A, Ayral AM, Mendes T, Desai S, Goate AM, Kauwe JSK, Leroux F, Herledan A, Demiautte F, Bauer C, Checler F, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Albert M, Moghekar A, O'Brien R, Peskind ER, Malmanche N, Schellenberg GD, Dourlen P, Song OR, Cruchaga C, Amouyel P, Deprez B, Brodin P, Lambert JC; ADGC, Alzheimer’s Disease Neuroimaging Initiative.

Acta Neuropathol. 2017 Jun;133(6):955-966. doi: 10.1007/s00401-016-1652-z. Epub 2016 Dec 8.

19.

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes.

Del Prete D, Suski JM, Oulès B, Debayle D, Gay AS, Lacas-Gervais S, Bussiere R, Bauer C, Pinton P, Paterlini-Bréchot P, Wieckowski MR, Checler F, Chami M.

J Alzheimers Dis. 2017;55(4):1549-1570. doi: 10.3233/JAD-160953.

20.

Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1.

Gerakis Y, Dunys J, Bauer C, Checler F.

Sci Rep. 2016 Nov 17;6:37436. doi: 10.1038/srep37436.

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