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Items: 1 to 20 of 112


Intercellular Communication between Hepatic Cells in Liver Diseases.

Sato K, Kennedy L, Liangpunsakul S, Kusumanchi P, Yang Z, Meng F, Glaser S, Francis H, Alpini G.

Int J Mol Sci. 2019 May 2;20(9). pii: E2180. doi: 10.3390/ijms20092180. Review.


Dual Role of Bile Acids on the Biliary Epithelium: Friend or Foe?

Baiocchi L, Zhou T, Liangpunsakul S, Lenci I, Santopaolo F, Meng F, Kennedy L, Glaser S, Francis H, Alpini G.

Int J Mol Sci. 2019 Apr 16;20(8). pii: E1869. doi: 10.3390/ijms20081869. Review.


Preclinical insights into cholangiopathies: disease modeling and emerging therapeutic targets.

Sato K, Glaser S, Kennedy L, Liangpunsakul S, Meng F, Francis H, Alpini G.

Expert Opin Ther Targets. 2019 Jun;23(6):461-472. doi: 10.1080/14728222.2019.1608950. Epub 2019 Apr 22.


Hepatitis C Virus Infection and Cholangiocarcinoma: An Insight into Epidemiologic Evidences and Hypothetical Mechanisms of Oncogenesis.

Navas MC, Glaser S, Dhruv H, Celinski S, Alpini G, Meng F.

Am J Pathol. 2019 Jun;189(6):1122-1132. doi: 10.1016/j.ajpath.2019.01.018. Epub 2019 Apr 4. Review.



Sato K, Meng F, Alpini G.

Hepatology. 2019 Mar 26. doi: 10.1002/hep.30619. [Epub ahead of print]


Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.

Chen L, Zhou T, Wu N, O'Brien A, Venter J, Ceci L, Kyritsi K, Onori P, Gaudio E, Sybenga A, Xie L, Wu C, Fabris L, Invernizzi P, Zawieja D, Liangpunsakul S, Meng F, Francis H, Alpini G, Huang Q, Glaser S.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1525-1539. doi: 10.1016/j.bbadis.2019.03.002. Epub 2019 Mar 16.


Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 Knockout Mice via Lethal-7 microRNA.

McDaniel K, Wu N, Zhou T, Huang L, Sato K, Venter J, Ceci L, Chen D, Ramos-Lorenzo S, Invernizzi P, Bernuzzi F, Wu C, Francis H, Glaser S, Alpini G, Meng F.

Hepatology. 2019 Feb 5. doi: 10.1002/hep.30542. [Epub ahead of print]


Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes.

Wan Y, Ceci L, Wu N, Zhou T, Chen L, Venter J, Francis H, Bernuzzi F, Invernizzi P, Kyritsi K, Baker P, Huang Q, Wu C, Sybenga A, Alpini G, Meng F, Glaser S.

Lab Invest. 2019 Jan 30. doi: 10.1038/s41374-018-0178-5. [Epub ahead of print]


Regulation of adipose tissue inflammation by adenosine 2A receptor in obese mice.

Pei Y, Li H, Cai Y, Zhou J, Luo X, Ma L, McDaniel K, Zeng T, Chen Y, Qian X, Huo Y, Glaser S, Meng F, Alpini G, Chen L, Wu C.

J Endocrinol. 2018 Dec 1;239(3):365-376. doi: 10.1530/JOE-18-0169.


Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice.

Luo X, Li H, Ma L, Zhou J, Guo X, Woo SL, Pei Y, Knight LR, Deveau M, Chen Y, Qian X, Xiao X, Li Q, Chen X, Huo Y, McDaniel K, Francis H, Glaser S, Meng F, Alpini G, Wu C.

Gastroenterology. 2018 Dec;155(6):1971-1984.e4. doi: 10.1053/j.gastro.2018.09.010. Epub 2018 Sep 10.


Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2-/- mice and human primary sclerosing cholangitis.

Meng F, Kennedy L, Hargrove L, Demieville J, Jones H, Madeka T, Karstens A, Chappell K, Alpini G, Sybenga A, Invernizzi P, Bernuzzi F, DeMorrow S, Francis H.

Lab Invest. 2018 Nov;98(11):1465-1477. doi: 10.1038/s41374-018-0101-0. Epub 2018 Aug 24.


Complex bile duct network formation within liver decellularized extracellular matrix hydrogels.

Lewis PL, Su J, Yan M, Meng F, Glaser SS, Alpini GD, Green RM, Sosa-Pineda B, Shah RN.

Sci Rep. 2018 Aug 15;8(1):12220. doi: 10.1038/s41598-018-30433-6.


Ductular Reaction in Liver Diseases: Pathological Mechanisms and Translational Significances.

Sato K, Marzioni M, Meng F, Francis H, Glaser S, Alpini G.

Hepatology. 2019 Jan;69(1):420-430. doi: 10.1002/hep.30150. Epub 2018 Dec 27. Review.


The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence.

Wu N, Meng F, Zhou T, Venter J, Giang TK, Kyritsi K, Wu C, Alvaro D, Onori P, Mancinelli R, Gaudio E, Francis H, Alpini G, Glaser S, Franchitto A.

Am J Pathol. 2018 Oct;188(10):2264-2280. doi: 10.1016/j.ajpath.2018.06.015. Epub 2018 Jul 21.


Author Correction: The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles.

Sato K, Meng F, Venter J, Giang T, Glaser S, Alpini G.

Sci Rep. 2018 Jul 20;8(1):11238. doi: 10.1038/s41598-018-29609-x.


Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.

Zhou T, Wu N, Meng F, Venter J, Giang TK, Francis H, Kyritsi K, Wu C, Franchitto A, Alvaro D, Marzioni M, Onori P, Mancinelli R, Gaudio E, Glaser S, Alpini G.

Lab Invest. 2018 Nov;98(11):1449-1464. doi: 10.1038/s41374-018-0093-9. Epub 2018 Jul 5.


Knockout of microRNA-21 attenuates alcoholic hepatitis through the VHL/NF-κB signaling pathway in hepatic stellate cells.

Wu N, McDaniel K, Zhou T, Ramos-Lorenzo S, Wu C, Huang L, Chen D, Annable T, Francis H, Glaser S, Alpini G, Meng F.

Am J Physiol Gastrointest Liver Physiol. 2018 Sep 1;315(3):G385-G398. doi: 10.1152/ajpgi.00111.2018. Epub 2018 May 31.


Biliary epithelium: A neuroendocrine compartment in cholestatic liver disease.

Ehrlich L, Scrushy M, Meng F, Lairmore TC, Alpini G, Glaser S.

Clin Res Hepatol Gastroenterol. 2018 Sep;42(4):296-305. doi: 10.1016/j.clinre.2018.03.009. Epub 2018 Apr 17. Review.


Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2-/- mice and human cholangiocarcinoma tumorigenesis.

Kennedy L, Hargrove L, Demieville J, Karstens W, Jones H, DeMorrow S, Meng F, Invernizzi P, Bernuzzi F, Alpini G, Smith S, Akers A, Meadows V, Francis H.

Hepatology. 2018 Mar 30. doi: 10.1002/hep.29898. [Epub ahead of print]


α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.

Ehrlich L, O'Brien A, Hall C, White T, Chen L, Wu N, Venter J, Scrushy M, Mubarak M, Meng F, Dostal D, Wu C, Lairmore TC, Alpini G, Glaser S.

Gene Expr. 2018 Aug 22;18(3):197-207. doi: 10.3727/105221618X15216453076707. Epub 2018 Mar 26.

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