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Items: 1 to 20 of 57


From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei.

Gonçalves TC, Benoit E, Kurz M, Lucarain L, Fouconnier S, Combemale S, Jaquillard L, Schombert B, Chambard JM, Boukaiba R, Hessler G, Bohme A, Bialy L, Hourcade S, Béroud R, De Waard M, Servent D, Partiseti M.

Br J Pharmacol. 2019 May;176(9):1298-1314. doi: 10.1111/bph.14628. Epub 2019 Apr 9.


Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth.

Cerles O, Gonçalves TC, Chouzenoux S, Benoit E, Schmitt A, Bennett Saidu NE, Kavian N, Chéreau C, Gobeaux C, Weill B, Coriat R, Nicco C, Batteux F.

Acta Neuropathol Commun. 2019 Jan 18;7(1):9. doi: 10.1186/s40478-019-0657-y.


Corrigendum: The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons.

Gonçalves TC, Benoit E, Partiseti M, Servent D.

Front Pharmacol. 2018 Oct 24;9:1241. doi: 10.3389/fphar.2018.01241. eCollection 2018.


The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons.

Gonçalves TC, Benoit E, Partiseti M, Servent D.

Front Pharmacol. 2018 Sep 4;9:1000. doi: 10.3389/fphar.2018.01000. eCollection 2018. Review. Erratum in: Front Pharmacol. 2018 Oct 24;9:1241.


23rd and 24th Meetings of the French society of toxinology (SFET): Special issue on "Toxins: Immunity, inflammation and pain".

Benoit E, Barbier J, Molgó J.

Toxicon. 2018 Jul;149:1-5. doi: 10.1016/j.toxicon.2018.04.020. Epub 2018 Apr 25. No abstract available.


Direct evidence for high affinity blockade of NaV1.6 channel subtype by huwentoxin-IV spider peptide, using multiscale functional approaches.

Gonçalves TC, Boukaiba R, Molgó J, Amar M, Partiseti M, Servent D, Benoit E.

Neuropharmacology. 2018 May 1;133:404-414. doi: 10.1016/j.neuropharm.2018.02.016. Epub 2018 Feb 21.


Natural polymeric 3-alkylpyridinium salt affects vertebrate skeletal muscle contractility by preferentially blocking neuromuscular transmission.

Žužek MC, Grandič M, Benoit E, Frangež R.

Toxicol Lett. 2017 Nov 5;281:95-101. doi: 10.1016/j.toxlet.2017.09.007. Epub 2017 Sep 20.


Ostreolysin A/Pleurotolysin B and Equinatoxins: Structure, Function and Pathophysiological Effects of These Pore-Forming Proteins.

Frangež R, Šuput D, Molgó J, Benoit E.

Toxins (Basel). 2017 Apr 5;9(4). pii: E128. doi: 10.3390/toxins9040128. Review.


Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors.

Molgó J, Marchot P, Aráoz R, Benoit E, Iorga BI, Zakarian A, Taylor P, Bourne Y, Servent D.

J Neurochem. 2017 Aug;142 Suppl 2:41-51. doi: 10.1111/jnc.13995. Epub 2017 Mar 21. Review.


Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response.

Cerles O, Benoit E, Chéreau C, Chouzenoux S, Morin F, Guillaumot MA, Coriat R, Kavian N, Loussier T, Santulli P, Marcellin L, Saidu NE, Weill B, Batteux F, Nicco C.

Mol Cancer Ther. 2017 Feb;16(2):300-311. doi: 10.1158/1535-7163.MCT-16-0326. Epub 2016 Dec 15.


The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors.

Couesnon A, Aráoz R, Iorga BI, Benoit E, Reynaud M, Servent D, Molgó J.

Toxins (Basel). 2016 Aug 24;8(9). pii: E249. doi: 10.3390/toxins8090249.


Special Issue on "Toxins: New targets and new functions".

Benoit E, Barbier J, Popoff MR, Faure G, Molgó J, Servent D.

Toxicon. 2016 Jun 15;116:1-3. doi: 10.1016/j.toxicon.2016.03.012. Epub 2016 Mar 17. No abstract available.


Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice.

Chali F, Desseille C, Houdebine L, Benoit E, Rouquet T, Bariohay B, Lopes P, Branchu J, Della Gaspera B, Pariset C, Chanoine C, Charbonnier F, Biondi O.

J Physiol. 2016 Apr 1;594(7):1931-52. doi: 10.1113/JP271361. Epub 2016 Feb 27.


Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease.

Khan MM, Lustrino D, Silveira WA, Wild F, Straka T, Issop Y, O'Connor E, Cox D, Reischl M, Marquardt T, Labeit D, Labeit S, Benoit E, Molgó J, Lochmüller H, Witzemann V, Kettelhut IC, Navegantes LC, Pozzan T, Rudolf R.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):746-50. doi: 10.1073/pnas.1524272113. Epub 2016 Jan 5. Erratum in: Proc Natl Acad Sci U S A. 2017 Jun 19;:.


The Neurotoxic Effect of 13,19-Didesmethyl and 13-Desmethyl Spirolide C Phycotoxins Is Mainly Mediated by Nicotinic Rather Than Muscarinic Acetylcholine Receptors.

Aráoz R, Ouanounou G, Iorga BI, Goudet A, Alili D, Amar M, Benoit E, Molgó J, Servent D.

Toxicol Sci. 2015 Sep;147(1):156-67. doi: 10.1093/toxsci/kfv119. Epub 2015 Jun 10.


Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α1(2)βγδ nAChRs.

Bourne Y, Sulzenbacher G, Radić Z, Aráoz R, Reynaud M, Benoit E, Zakarian A, Servent D, Molgó J, Taylor P, Marchot P.

Structure. 2015 Jun 2;23(6):1106-15. doi: 10.1016/j.str.2015.04.009. Epub 2015 May 21.


Effect of the ostreolysin A/pleurotolysin B pore-forming complex on neuroblastoma cell morphology and intracellular Ca²⁺ activity.

Vrecl M, Babnik M, Diacci U, Benoit E, Frangež R.

Toxicol Sci. 2015 Apr;144(2):276-83. doi: 10.1093/toxsci/kfu316. Epub 2015 Jan 2.


Special Issue on "freshwater and marine toxins".

Benoit E, Mattei C, Barbier J, Marchot P, Molgó J, Servent D.

Toxicon. 2014 Dec;91:1-4. doi: 10.1016/j.toxicon.2014.11.217. Epub 2014 Nov 20. No abstract available.


Isolation, purification and functional characterization of alpha-BnIA from Conus bandanus venom.

Nguyen B, Le Caer JP, Aráoz R, Thai R, Lamthanh H, Benoit E, Molgó J.

Toxicon. 2014 Dec;91:155-63. doi: 10.1016/j.toxicon.2014.10.006. Epub 2014 Oct 15.


Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.

Stivala CE, Benoit E, Aráoz R, Servent D, Novikov A, Molgó J, Zakarian A.

Nat Prod Rep. 2015 Mar;32(3):411-35. doi: 10.1039/c4np00089g. Review.

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