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Items: 1 to 20 of 76

1.

Meeting report: Fourth Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS).

Le Grice S, Maccioni E, Corona A, Parolin C, Tramontano E.

Antiviral Res. 2019 Feb;162:110-117. doi: 10.1016/j.antiviral.2018.12.013. Epub 2018 Dec 23. Review.

PMID:
30586561
2.

Insights into Ebola Virus VP35 and VP24 Interferon inhibitory functions and their initial exploitation as drug targets

Fanunza E, Frau A, Corona A, Tramontano E.

Infect Disord Drug Targets. 2018 Nov 23. doi: 10.2174/1871526519666181123145540. [Epub ahead of print]

PMID:
30468131
3.

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors.

Massari S, Corona A, Distinto S, Desantis J, Caredda A, Sabatini S, Manfroni G, Felicetti T, Cecchetti V, Pannecouque C, Maccioni E, Tramontano E, Tabarrini O.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):55-74. doi: 10.1080/14756366.2018.1523901.

4.

Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques.

Costa G, Rocca R, Corona A, Grandi N, Moraca F, Romeo I, Talarico C, Gagliardi MG, Ambrosio FA, Ortuso F, Alcaro S, Distinto S, Maccioni E, Tramontano E, Artese A.

Eur J Med Chem. 2019 Jan 1;161:1-10. doi: 10.1016/j.ejmech.2018.10.029. Epub 2018 Oct 13.

PMID:
30342421
5.

Identification of Myricetin as an Ebola Virus VP35-Double-Stranded RNA Interaction Inhibitor through a Novel Fluorescence-Based Assay.

Daino GL, Frau A, Sanna C, Rigano D, Distinto S, Madau V, Esposito F, Fanunza E, Bianco G, Taglialatela-Scafati O, Zinzula L, Maccioni E, Corona A, Tramontano E.

Biochemistry. 2018 Nov 6;57(44):6367-6378. doi: 10.1021/acs.biochem.8b00892. Epub 2018 Oct 22.

PMID:
30298725
6.

Human Endogenous Retroviruses Are Ancient Acquired Elements Still Shaping Innate Immune Responses.

Grandi N, Tramontano E.

Front Immunol. 2018 Sep 10;9:2039. doi: 10.3389/fimmu.2018.02039. eCollection 2018. Review.

7.

Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studies.

Poongavanam V, Corona A, Steinmann C, Scipione L, Grandi N, Pandolfi F, Di Santo R, Costi R, Esposito F, Tramontano E, Kongsted J.

Medchemcomm. 2018 Feb 1;9(3):562-575. doi: 10.1039/c7md00600d. eCollection 2018 Mar 1.

8.

On the S-layer of Thermus thermophilus and the assembling of its main protein SlpA.

Farci D, Farci SF, Esposito F, Tramontano E, Kirkpatrick J, Piano D.

Biochim Biophys Acta Biomembr. 2018 Aug;1860(8):1554-1562. doi: 10.1016/j.bbamem.2018.05.010. Epub 2018 May 25.

PMID:
29803693
9.

Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops.

Virgilio A, Amato T, Petraccone L, Esposito F, Grandi N, Tramontano E, Romero R, Haider S, Gomez-Monterrey I, Novellino E, Mayol L, Esposito V, Galeone A.

Sci Rep. 2018 May 10;8(1):7447. doi: 10.1038/s41598-018-25720-1.

10.

Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.

Sanna C, Scognamiglio M, Fiorentino A, Corona A, Graziani V, Caredda A, Cortis P, Montisci M, Ceresola ER, Canducci F, Poli F, Tramontano E, Esposito F.

PLoS One. 2018 Mar 30;13(3):e0195168. doi: 10.1371/journal.pone.0195168. eCollection 2018.

11.

HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity.

Grandi N, Tramontano E.

Front Microbiol. 2018 Mar 14;9:462. doi: 10.3389/fmicb.2018.00462. eCollection 2018. Review.

12.

Development and Validation of a Novel Dual Luciferase Reporter Gene Assay to Quantify Ebola Virus VP24 Inhibition of IFN Signaling.

Fanunza E, Frau A, Sgarbanti M, Orsatti R, Corona A, Tramontano E.

Viruses. 2018 Feb 24;10(2). pii: E98. doi: 10.3390/v10020098.

13.

Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein.

Ramaswamy VK, Di Palma F, Vargiu AV, Corona A, Piano D, Ruggerone P, Zinzula L, Tramontano E.

Virus Res. 2018 Mar 2;247:61-70. doi: 10.1016/j.virusres.2018.02.003. Epub 2018 Feb 7.

PMID:
29427597
14.

Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy).

Sanna C, Rigano D, Corona A, Piano D, Formisano C, Farci D, Franzini G, Ballero M, Chianese G, Tramontano E, Taglialatela-Scafati O, Esposito F.

Nat Prod Res. 2018 Feb 4:1-6. doi: 10.1080/14786419.2018.1434649. [Epub ahead of print]

PMID:
29397771
15.

HERV-W group evolutionary history in non-human primates: characterization of ERV-W orthologs in Catarrhini and related ERV groups in Platyrrhini.

Grandi N, Cadeddu M, Blomberg J, Mayer J, Tramontano E.

BMC Evol Biol. 2018 Jan 19;18(1):6. doi: 10.1186/s12862-018-1125-1.

16.

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion.

Grandi N, Cadeddu M, Pisano MP, Esposito F, Blomberg J, Tramontano E.

Mob DNA. 2017 Nov 2;8:15. doi: 10.1186/s13100-017-0099-7. eCollection 2017.

17.

Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.

Corona A, Onnis V, Deplano A, Bianco G, Demurtas M, Distinto S, Cheng YC, Alcaro S, Esposito F, Tramontano E.

Pathog Dis. 2017 Aug 31;75(6). doi: 10.1093/femspd/ftx078.

18.

Broad-range potential of Asphodelus microcarpus leaves extract for drug development.

Di Petrillo A, Fais A, Pintus F, Santos-Buelga C, González-Paramás AM, Piras V, Orrù G, Mameli A, Tramontano E, Frau A.

BMC Microbiol. 2017 Jul 14;17(1):159. doi: 10.1186/s12866-017-1068-5.

20.

Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.

Esposito F, Mandrone M, Del Vecchio C, Carli I, Distinto S, Corona A, Lianza M, Piano D, Tacchini M, Maccioni E, Cottiglia F, Saccon E, Poli F, Parolin C, Tramontano E.

Pathog Dis. 2017 Aug 31;75(6). doi: 10.1093/femspd/ftx065.

PMID:
28637198

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